4KBJ | Genus

Total Genus 119

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	119
sequence length	386
structure length	384
Chain Sequence	PRGSHMMLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGEPITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFF

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Mycobacterium tuberculosis
publication title	Structure of the Mtb CarD/RNAP beta-Lobes Complex Reveals the Molecular Basis of Interaction and Presents a Distinct DNA-Binding Domain for Mtb CarD. pubmed doi rcsb
molecule keywords	DNA-directed RNA polymerase subunit beta
total genus	119
structure length	384
sequence length	386
chains with identical sequence	B
ec nomenclature	ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date	2013-04-23

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF04561	RNA_pol_Rpb2_2	RNA polymerase Rpb2, domain 2

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.1110.10	Alpha Beta	Alpha-Beta Complex	Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3	RNA polymerase Rpb2, domain 2	4kbjA02

3LTIA 3S16B 3K7AB 2A6HC 1TWCB 4Y7NB 4BY7B 3M3YB 1Y1VB 1TWHB 4GZYC 2R93B 5M3MB 5M5XB 3S1RB 4A3GB 1Y1WB 2BE5C 1YNJC 1SFOB 3GTKB 3FKIB 1I50B 4A3DB 2JA7B 3S2HB 4AYBB 1TWFB 1IW7C 1ZYRC 2JA6B 3GTPB 4KBMA 4BY1B 2E2HB 3HKZB 3GTLB 1HQMC 3RZDB 4A3EB 4BBSB 5C4XB 4LK1C 1I6VC 4QIWB 4G7HC 4C3JB 5M5WB 3RZOB 3GTGB 3H3VC 2Y0SB 5M3FB 3S17B 3S1MB 2NVQB 2E2IB 4KBJA 1SMYC 3I4MB 3H0GB 4A93B 3GTOB 3GTJB 3HOZB 1K83B 4A3IB 4A3JB 4A3KB 4A3MB 3S1NB 3PO3B 1R9TB 3HOVB 3S1QB 3HOXB 4C3HB 2A6EC 1TWAB 2JA5B 2NVYB 3EQLC 3GTMB 4G7OC 3S15B 5C3EB 3I4NB 2CW0C 3HOWB 4A3BB 3CQZB 3HOYB 3S2DB 4LJZC 2R92B 2R7ZB 2WAQB 1I6HB 4C3IB 2YU9B 2O5JC 4BBRB 2B63B 3GTQB 1WCMB 2VUMB 2A69C 2PPBC 3M4OB 5C44B 4G7ZC 5M5YB 2PMZB 2O5IC 2A68C 2JA8B 1YNNC 1I3QB 4A3FB 3PO2B 5C4JB 2E2JB 2NVXB 2NVTB 1TWGB 4C2MB 3HOUB 3DXJC 3S14B 2WB1B
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3LTI A;  3S16 B;  3K7A B;  2A6H C;  1TWC B;  4Y7N B;  4BY7 B;  3M3Y B;  1Y1V B;  1TWH B;  4GZY C;  2R93 B;  5M3M B;  5M5X B;  3S1R B;  4A3G B;  1Y1W B;  2BE5 C;  1YNJ C;  1SFO B;  3GTK B;  3FKI B;  1I50 B;  4A3D B;  2JA7 B;  3S2H B;  4AYB B;  1TWF B;  1IW7 C;  1ZYR C;  2JA6 B;  3GTP B;  4KBM A;  4BY1 B;  2E2H B;  3HKZ B;  3GTL B;  1HQM C;  3RZD B;  4A3E B;  4BBS B;  5C4X B;  4LK1 C;  1I6V C;  4QIW B;  4G7H C;  4C3J B;  5M5W B;  3RZO B;  3GTG B;  3H3V C;  2Y0S B;  5M3F B;  3S17 B;  3S1M B;  2NVQ B;  2E2I B;  4KBJ A;  1SMY C;  3I4M B;  3H0G B;  4A93 B;  3GTO B;  3GTJ B;  3HOZ B;  1K83 B;  4A3I B;  4A3J B;  4A3K B;  4A3M B;  3S1N B;  3PO3 B;  1R9T B;  3HOV B;  3S1Q B;  3HOX B;  4C3H B;  2A6E C;  1TWA B;  2JA5 B;  2NVY B;  3EQL C;  3GTM B;  4G7O C;  3S15 B;  5C3E B;  3I4N B;  2CW0 C;  3HOW B;  4A3B B;  3CQZ B;  3HOY B;  3S2D B;  4LJZ C;  2R92 B;  2R7Z B;  2WAQ B;  1I6H B;  4C3I B;  2YU9 B;  2O5J C;  4BBR B;  2B63 B;  3GTQ B;  1WCM B;  2VUM B;  2A69 C;  2PPB C;  3M4O B;  5C44 B;  4G7Z C;  5M5Y B;  2PMZ B;  2O5I C;  2A68 C;  2JA8 B;  1YNN C;  1I3Q B;  4A3F B;  3PO2 B;  5C4J B;  2E2J B;  2NVX B;  2NVT B;  1TWG B;  4C2M B;  3HOU B;  3DXJ C;  3S14 B;  2WB1 B; 
#chains in the Genus database with same CATH topology
 3LTI A;  3S16 B;  3K7A B;  2A6H C;  1TWC B;  4Y7N B;  4BY7 B;  3M3Y B;  1Y1V B;  1TWH B;  4GZY C;  2R93 B;  5M3M B;  5M5X B;  3S1R B;  4A3G B;  1Y1W B;  2BE5 C;  1YNJ C;  1SFO B;  3GTK B;  3FKI B;  1I50 B;  4A3D B;  2JA7 B;  3S2H B;  4AYB B;  1TWF B;  1IW7 C;  1ZYR C;  2JA6 B;  3GTP B;  4KBM A;  4BY1 B;  2E2H B;  3HKZ B;  3GTL B;  1HQM C;  3RZD B;  4A3E B;  4BBS B;  5C4X B;  4LK1 C;  1I6V C;  4QIW B;  4G7H C;  4C3J B;  5M5W B;  3RZO B;  3GTG B;  3H3V C;  2Y0S B;  5M3F B;  3S17 B;  3S1M B;  2NVQ B;  2E2I B;  4KBJ A;  1SMY C;  3I4M B;  3H0G B;  4A93 B;  3GTO B;  3GTJ B;  3HOZ B;  1K83 B;  4A3I B;  4A3J B;  4A3K B;  4A3M B;  3S1N B;  3PO3 B;  1R9T B;  3HOV B;  3S1Q B;  3HOX B;  4C3H B;  2A6E C;  1TWA B;  2JA5 B;  2NVY B;  3EQL C;  3GTM B;  4G7O C;  3S15 B;  5C3E B;  3I4N B;  2CW0 C;  3HOW B;  4A3B B;  3CQZ B;  3HOY B;  3S2D B;  4LJZ C;  2R92 B;  2R7Z B;  2WAQ B;  1I6H B;  4C3I B;  2YU9 B;  2O5J C;  4BBR B;  2B63 B;  3GTQ B;  1WCM B;  2VUM B;  2A69 C;  2PPB C;  3M4O B;  5C44 B;  4G7Z C;  5M5Y B;  2PMZ B;  2O5I C;  2A68 C;  2JA8 B;  1YNN C;  1I3Q B;  4A3F B;  3PO2 B;  5C4J B;  2E2J B;  2NVX B;  2NVT B;  1TWG B;  4C2M B;  3HOU B;  3DXJ C;  3S14 B;  2WB1 B; 
#chains in the Genus database with same CATH homology
 3LTI A;  3S16 B;  3K7A B;  2A6H C;  1TWC B;  4Y7N B;  4BY7 B;  3M3Y B;  1Y1V B;  1TWH B;  4GZY C;  2R93 B;  5M3M B;  5M5X B;  3S1R B;  4A3G B;  1Y1W B;  2BE5 C;  1YNJ C;  1SFO B;  3GTK B;  3FKI B;  1I50 B;  4A3D B;  2JA7 B;  3S2H B;  4AYB B;  1TWF B;  1IW7 C;  1ZYR C;  2JA6 B;  3GTP B;  4KBM A;  4BY1 B;  2E2H B;  3HKZ B;  3GTL B;  1HQM C;  3RZD B;  4A3E B;  4BBS B;  5C4X B;  4LK1 C;  1I6V C;  4QIW B;  4G7H C;  4C3J B;  5M5W B;  3RZO B;  3GTG B;  3H3V C;  2Y0S B;  5M3F B;  3S17 B;  3S1M B;  2NVQ B;  2E2I B;  4KBJ A;  1SMY C;  3I4M B;  3H0G B;  4A93 B;  3GTO B;  3GTJ B;  3HOZ B;  1K83 B;  4A3I B;  4A3J B;  4A3K B;  4A3M B;  3S1N B;  3PO3 B;  1R9T B;  3HOV B;  3S1Q B;  3HOX B;  4C3H B;  2A6E C;  1TWA B;  2JA5 B;  2NVY B;  3EQL C;  3GTM B;  4G7O C;  3S15 B;  5C3E B;  3I4N B;  2CW0 C;  3HOW B;  4A3B B;  3CQZ B;  3HOY B;  3S2D B;  4LJZ C;  2R92 B;  2R7Z B;  2WAQ B;  1I6H B;  4C3I B;  2YU9 B;  2O5J C;  4BBR B;  2B63 B;  3GTQ B;  1WCM B;  2VUM B;  2A69 C;  2PPB C;  3M4O B;  5C44 B;  4G7Z C;  5M5Y B;  2PMZ B;  2O5I C;  2A68 C;  2JA8 B;  1YNN C;  1I3Q B;  4A3F B;  3PO2 B;  5C4J B;  2E2J B;  2NVX B;  2NVT B;  1TWG B;  4C2M B;  3HOU B;  3DXJ C;  3S14 B;  2WB1 B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4KBJA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations