4KBJA

Structure of mtb rnap beta subunit b1 and b2 domains
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
386
structure length
384
Chain Sequence
PRGSHMMLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGEPITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Mtb CarD/RNAP beta-Lobes Complex Reveals the Molecular Basis of Interaction and Presents a Distinct DNA-Binding Domain for Mtb CarD.
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords DNA-directed RNA polymerase subunit beta
total genus 119
structure length 384
sequence length 386
chains with identical sequence B
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2013-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04561 RNA_pol_Rpb2_2 RNA polymerase Rpb2, domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1110.10 Alpha Beta Alpha-Beta Complex Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 RNA polymerase Rpb2, domain 2 4kbjA02
4LK1C 3LTIA 3PO2B 2NVYB 4A3IB 1YNJC 1WCMB 4A3GB 3S2HB 1SMYC 5M3FB 3GTLB 3GTKB 3S1QB 3K7AB 2NVXB 2NVTB 3GTPB 1I6HB 3I4MB 5M5WB 4A3KB 1SFOB 5M5XB 5C4XB 4C3IB 2JA5B 5M3MB 5C44B 4A93B 1K83B 2CW0C 1TWFB 3HOUB 2PPBC 3GTQB 2WB1B 2JA7B 4G7HC 2YU9B 3GTMB 1I6VC 1I3QB 5C3EB 4BBRB 2R92B 2BE5C 1TWCB 4KBMA 2B63B 2NVQB 4C2MB 3H0GB 3HOYB 1IW7C 2Y0SB 1Y1WB 2VUMB 2A6EC 4BY1B 3RZDB 4KBJA 2WAQB 4GZYC 3S15B 2E2IB 4BBSB 2E2HB 3EQLC 4A3FB 4A3DB 2PMZB 3S1MB 3GTOB 3HOWB 4LJZC 3S1NB 2O5IC 3HOXB 3GTJB 3M4OB 4C3JB 4G7ZC 1R9TB 3HKZB 2A68C 3DXJC 3I4NB 3HOZB 2JA8B 1I50B 4AYBB 3S1RB 2R93B 2E2JB 4BY7B 1YNNC 2R7ZB 3S17B 4C3HB 3HOVB 4A3EB 1TWAB 3S2DB 3PO3B 2A6HC 3GTGB 2A69C 3M3YB 1ZYRC 3RZOB 3FKIB 3S14B 4QIWB 4G7OC 4A3JB 5C4JB 4A3BB 3CQZB 1HQMC 3S16B 4Y7NB 1TWGB 2O5JC 1TWHB 5M5YB 1Y1VB 4A3MB 3H3VC 2JA6B
chains in the Genus database with same CATH superfamily
4LK1C 3LTIA 3PO2B 2NVYB 4A3IB 1YNJC 1WCMB 4A3GB 3S2HB 1SMYC 5M3FB 3GTLB 3GTKB 3S1QB 3K7AB 2NVXB 2NVTB 3GTPB 1I6HB 3I4MB 5M5WB 4A3KB 1SFOB 5M5XB 5C4XB 4C3IB 2JA5B 5M3MB 5C44B 4A93B 1K83B 2CW0C 1TWFB 3HOUB 2PPBC 3GTQB 2WB1B 2JA7B 4G7HC 2YU9B 3GTMB 1I6VC 1I3QB 5C3EB 4BBRB 2R92B 2BE5C 1TWCB 4KBMA 2B63B 2NVQB 4C2MB 3H0GB 3HOYB 1IW7C 2Y0SB 1Y1WB 2VUMB 2A6EC 4BY1B 3RZDB 4KBJA 2WAQB 4GZYC 3S15B 2E2IB 4BBSB 2E2HB 3EQLC 4A3FB 4A3DB 2PMZB 3S1MB 3GTOB 3HOWB 4LJZC 3S1NB 2O5IC 3HOXB 3GTJB 3M4OB 4C3JB 4G7ZC 1R9TB 3HKZB 2A68C 3DXJC 3I4NB 3HOZB 2JA8B 1I50B 4AYBB 3S1RB 2R93B 2E2JB 4BY7B 1YNNC 2R7ZB 3S17B 4C3HB 3HOVB 4A3EB 1TWAB 3S2DB 3PO3B 2A6HC 3GTGB 2A69C 3M3YB 1ZYRC 3RZOB 3FKIB 3S14B 4QIWB 4G7OC 4A3JB 5C4JB 4A3BB 3CQZB 1HQMC 3S16B 4Y7NB 1TWGB 2O5JC 1TWHB 5M5YB 1Y1VB 4A3MB 3H3VC 2JA6B
chains in the Genus database with same CATH topology
4LK1C 3LTIA 3PO2B 2NVYB 4A3IB 1YNJC 1WCMB 4A3GB 3S2HB 1SMYC 5M3FB 3GTLB 3GTKB 3S1QB 3K7AB 2NVXB 2NVTB 3GTPB 1I6HB 3I4MB 5M5WB 4A3KB 1SFOB 5M5XB 5C4XB 4C3IB 2JA5B 5M3MB 5C44B 4A93B 1K83B 2CW0C 1TWFB 3HOUB 2PPBC 3GTQB 2WB1B 2JA7B 4G7HC 2YU9B 3GTMB 1I6VC 1I3QB 5C3EB 4BBRB 2R92B 2BE5C 1TWCB 4KBMA 2B63B 2NVQB 4C2MB 3H0GB 3HOYB 1IW7C 2Y0SB 1Y1WB 2VUMB 2A6EC 4BY1B 3RZDB 4KBJA 2WAQB 4GZYC 3S15B 2E2IB 4BBSB 2E2HB 3EQLC 4A3FB 4A3DB 2PMZB 3S1MB 3GTOB 3HOWB 4LJZC 3S1NB 2O5IC 3HOXB 3GTJB 3M4OB 4C3JB 4G7ZC 1R9TB 3HKZB 2A68C 3DXJC 3I4NB 3HOZB 2JA8B 1I50B 4AYBB 3S1RB 2R93B 2E2JB 4BY7B 1YNNC 2R7ZB 3S17B 4C3HB 3HOVB 4A3EB 1TWAB 3S2DB 3PO3B 2A6HC 3GTGB 2A69C 3M3YB 1ZYRC 3RZOB 3FKIB 3S14B 4QIWB 4G7OC 4A3JB 5C4JB 4A3BB 3CQZB 1HQMC 3S16B 4Y7NB 1TWGB 2O5JC 1TWHB 5M5YB 1Y1VB 4A3MB 3H3VC 2JA6B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LK1 C;  3LTI A;  3PO2 B;  2NVY B;  4A3I B;  1YNJ C;  1WCM B;  4A3G B;  3S2H B;  1SMY C;  5M3F B;  3GTL B;  3GTK B;  3S1Q B;  3K7A B;  2NVX B;  2NVT B;  3GTP B;  1I6H B;  3I4M B;  5M5W B;  4A3K B;  1SFO B;  5M5X B;  5C4X B;  4C3I B;  2JA5 B;  5M3M B;  5C44 B;  4A93 B;  1K83 B;  2CW0 C;  1TWF B;  3HOU B;  2PPB C;  3GTQ B;  2WB1 B;  2JA7 B;  4G7H C;  2YU9 B;  3GTM B;  1I6V C;  1I3Q B;  5C3E B;  4BBR B;  2R92 B;  2BE5 C;  1TWC B;  4KBM A;  2B63 B;  2NVQ B;  4C2M B;  3H0G B;  3HOY B;  1IW7 C;  2Y0S B;  1Y1W B;  2VUM B;  2A6E C;  4BY1 B;  3RZD B;  4KBJ A;  2WAQ B;  4GZY C;  3S15 B;  2E2I B;  4BBS B;  2E2H B;  3EQL C;  4A3F B;  4A3D B;  2PMZ B;  3S1M B;  3GTO B;  3HOW B;  4LJZ C;  3S1N B;  2O5I C;  3HOX B;  3GTJ B;  3M4O B;  4C3J B;  4G7Z C;  1R9T B;  3HKZ B;  2A68 C;  3DXJ C;  3I4N B;  3HOZ B;  2JA8 B;  1I50 B;  4AYB B;  3S1R B;  2R93 B;  2E2J B;  4BY7 B;  1YNN C;  2R7Z B;  3S17 B;  4C3H B;  3HOV B;  4A3E B;  1TWA B;  3S2D B;  3PO3 B;  2A6H C;  3GTG B;  2A69 C;  3M3Y B;  1ZYR C;  3RZO B;  3FKI B;  3S14 B;  4QIW B;  4G7O C;  4A3J B;  5C4J B;  4A3B B;  3CQZ B;  1HQM C;  3S16 B;  4Y7N B;  1TWG B;  2O5J C;  1TWH B;  5M5Y B;  1Y1V B;  4A3M B;  3H3V C;  2JA6 B; 
#chains in the Genus database with same CATH topology
 4LK1 C;  3LTI A;  3PO2 B;  2NVY B;  4A3I B;  1YNJ C;  1WCM B;  4A3G B;  3S2H B;  1SMY C;  5M3F B;  3GTL B;  3GTK B;  3S1Q B;  3K7A B;  2NVX B;  2NVT B;  3GTP B;  1I6H B;  3I4M B;  5M5W B;  4A3K B;  1SFO B;  5M5X B;  5C4X B;  4C3I B;  2JA5 B;  5M3M B;  5C44 B;  4A93 B;  1K83 B;  2CW0 C;  1TWF B;  3HOU B;  2PPB C;  3GTQ B;  2WB1 B;  2JA7 B;  4G7H C;  2YU9 B;  3GTM B;  1I6V C;  1I3Q B;  5C3E B;  4BBR B;  2R92 B;  2BE5 C;  1TWC B;  4KBM A;  2B63 B;  2NVQ B;  4C2M B;  3H0G B;  3HOY B;  1IW7 C;  2Y0S B;  1Y1W B;  2VUM B;  2A6E C;  4BY1 B;  3RZD B;  4KBJ A;  2WAQ B;  4GZY C;  3S15 B;  2E2I B;  4BBS B;  2E2H B;  3EQL C;  4A3F B;  4A3D B;  2PMZ B;  3S1M B;  3GTO B;  3HOW B;  4LJZ C;  3S1N B;  2O5I C;  3HOX B;  3GTJ B;  3M4O B;  4C3J B;  4G7Z C;  1R9T B;  3HKZ B;  2A68 C;  3DXJ C;  3I4N B;  3HOZ B;  2JA8 B;  1I50 B;  4AYB B;  3S1R B;  2R93 B;  2E2J B;  4BY7 B;  1YNN C;  2R7Z B;  3S17 B;  4C3H B;  3HOV B;  4A3E B;  1TWA B;  3S2D B;  3PO3 B;  2A6H C;  3GTG B;  2A69 C;  3M3Y B;  1ZYR C;  3RZO B;  3FKI B;  3S14 B;  4QIW B;  4G7O C;  4A3J B;  5C4J B;  4A3B B;  3CQZ B;  1HQM C;  3S16 B;  4Y7N B;  1TWG B;  2O5J C;  1TWH B;  5M5Y B;  1Y1V B;  4A3M B;  3H3V C;  2JA6 B; 
#chains in the Genus database with same CATH homology
 4LK1 C;  3LTI A;  3PO2 B;  2NVY B;  4A3I B;  1YNJ C;  1WCM B;  4A3G B;  3S2H B;  1SMY C;  5M3F B;  3GTL B;  3GTK B;  3S1Q B;  3K7A B;  2NVX B;  2NVT B;  3GTP B;  1I6H B;  3I4M B;  5M5W B;  4A3K B;  1SFO B;  5M5X B;  5C4X B;  4C3I B;  2JA5 B;  5M3M B;  5C44 B;  4A93 B;  1K83 B;  2CW0 C;  1TWF B;  3HOU B;  2PPB C;  3GTQ B;  2WB1 B;  2JA7 B;  4G7H C;  2YU9 B;  3GTM B;  1I6V C;  1I3Q B;  5C3E B;  4BBR B;  2R92 B;  2BE5 C;  1TWC B;  4KBM A;  2B63 B;  2NVQ B;  4C2M B;  3H0G B;  3HOY B;  1IW7 C;  2Y0S B;  1Y1W B;  2VUM B;  2A6E C;  4BY1 B;  3RZD B;  4KBJ A;  2WAQ B;  4GZY C;  3S15 B;  2E2I B;  4BBS B;  2E2H B;  3EQL C;  4A3F B;  4A3D B;  2PMZ B;  3S1M B;  3GTO B;  3HOW B;  4LJZ C;  3S1N B;  2O5I C;  3HOX B;  3GTJ B;  3M4O B;  4C3J B;  4G7Z C;  1R9T B;  3HKZ B;  2A68 C;  3DXJ C;  3I4N B;  3HOZ B;  2JA8 B;  1I50 B;  4AYB B;  3S1R B;  2R93 B;  2E2J B;  4BY7 B;  1YNN C;  2R7Z B;  3S17 B;  4C3H B;  3HOV B;  4A3E B;  1TWA B;  3S2D B;  3PO3 B;  2A6H C;  3GTG B;  2A69 C;  3M3Y B;  1ZYR C;  3RZO B;  3FKI B;  3S14 B;  4QIW B;  4G7O C;  4A3J B;  5C4J B;  4A3B B;  3CQZ B;  1HQM C;  3S16 B;  4Y7N B;  1TWG B;  2O5J C;  1TWH B;  5M5Y B;  1Y1V B;  4A3M B;  3H3V C;  2JA6 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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