4KBJA

Structure of mtb rnap beta subunit b1 and b2 domains
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
386
structure length
384
Chain Sequence
PRGSHMMLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGEPITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Mtb CarD/RNAP beta-Lobes Complex Reveals the Molecular Basis of Interaction and Presents a Distinct DNA-Binding Domain for Mtb CarD.
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords DNA-directed RNA polymerase subunit beta
total genus 119
structure length 384
sequence length 386
chains with identical sequence B
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2013-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04561 RNA_pol_Rpb2_2 RNA polymerase Rpb2, domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1110.10 Alpha Beta Alpha-Beta Complex Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 RNA polymerase Rpb2, domain 2 4kbjA02
3EQLC 4BY1B 2VUMB 2JA5B 1TWFB 2R93B 4BY7B 4C3JB 5M5YB 3S17B 5M3FB 3HKZB 3GTKB 1I6HB 3LTIA 3S1RB 3M3YB 3H0GB 2O5JC 4A3GB 1WCMB 1SMYC 2BE5C 2CW0C 3M4OB 1SFOB 2NVTB 5C4XB 2NVQB 2B63B 4LK1C 4KBJA 4GZYC 3HOYB 3I4MB 4A3DB 1R9TB 3GTLB 1YNJC 1ZYRC 3S2HB 4A3FB 4BBSB 4G7HC 3S1NB 4A93B 1TWGB 4A3MB 3HOVB 2PPBC 1TWCB 2O5IC 3HOUB 2Y0SB 4C3HB 4A3BB 2A6HC 5C3EB 5C4JB 4LJZC 2A6EC 2YU9B 2NVYB 1YNNC 5M5XB 3CQZB 1TWHB 1Y1WB 3HOZB 3GTGB 3GTOB 3I4NB 3HOXB 2WB1B 5M3MB 4A3JB 1I50B 2A69C 2WAQB 3K7AB 3RZOB 3GTJB 3S14B 2A68C 3GTPB 2R92B 4C2MB 1TWAB 3PO3B 2JA8B 3DXJC 3H3VC 4A3IB 2JA7B 5C44B 1HQMC 2R7ZB 2JA6B 4A3KB 2E2JB 3GTQB 1K83B 3S2DB 3S1MB 3PO2B 4G7ZC 1Y1VB 4C3IB 4KBMA 4A3EB 1I3QB 3S16B 4Y7NB 3GTMB 3HOWB 2E2IB 2E2HB 4AYBB 3RZDB 4G7OC 2PMZB 3S1QB 3S15B 5M5WB 1I6VC 2NVXB 1IW7C 4QIWB 4BBRB 3FKIB
chains in the Genus database with same CATH superfamily
3EQLC 4BY1B 2VUMB 2JA5B 1TWFB 2R93B 4BY7B 4C3JB 5M5YB 3S17B 5M3FB 3HKZB 3GTKB 1I6HB 3LTIA 3S1RB 3M3YB 3H0GB 2O5JC 4A3GB 1WCMB 1SMYC 2BE5C 2CW0C 3M4OB 1SFOB 2NVTB 5C4XB 2NVQB 2B63B 4LK1C 4KBJA 4GZYC 3HOYB 3I4MB 4A3DB 1R9TB 3GTLB 1YNJC 1ZYRC 3S2HB 4A3FB 4BBSB 4G7HC 3S1NB 4A93B 1TWGB 4A3MB 3HOVB 2PPBC 1TWCB 2O5IC 3HOUB 2Y0SB 4C3HB 4A3BB 2A6HC 5C3EB 5C4JB 4LJZC 2A6EC 2YU9B 2NVYB 1YNNC 5M5XB 3CQZB 1TWHB 1Y1WB 3HOZB 3GTGB 3GTOB 3I4NB 3HOXB 2WB1B 5M3MB 4A3JB 1I50B 2A69C 2WAQB 3K7AB 3RZOB 3GTJB 3S14B 2A68C 3GTPB 2R92B 4C2MB 1TWAB 3PO3B 2JA8B 3DXJC 3H3VC 4A3IB 2JA7B 5C44B 1HQMC 2R7ZB 2JA6B 4A3KB 2E2JB 3GTQB 1K83B 3S2DB 3S1MB 3PO2B 4G7ZC 1Y1VB 4C3IB 4KBMA 4A3EB 1I3QB 3S16B 4Y7NB 3GTMB 3HOWB 2E2IB 2E2HB 4AYBB 3RZDB 4G7OC 2PMZB 3S1QB 3S15B 5M5WB 1I6VC 2NVXB 1IW7C 4QIWB 4BBRB 3FKIB
chains in the Genus database with same CATH topology
3EQLC 4BY1B 2VUMB 2JA5B 1TWFB 2R93B 4BY7B 4C3JB 5M5YB 3S17B 5M3FB 3HKZB 3GTKB 1I6HB 3LTIA 3S1RB 3M3YB 3H0GB 2O5JC 4A3GB 1WCMB 1SMYC 2BE5C 2CW0C 3M4OB 1SFOB 2NVTB 5C4XB 2NVQB 2B63B 4LK1C 4KBJA 4GZYC 3HOYB 3I4MB 4A3DB 1R9TB 3GTLB 1YNJC 1ZYRC 3S2HB 4A3FB 4BBSB 4G7HC 3S1NB 4A93B 1TWGB 4A3MB 3HOVB 2PPBC 1TWCB 2O5IC 3HOUB 2Y0SB 4C3HB 4A3BB 2A6HC 5C3EB 5C4JB 4LJZC 2A6EC 2YU9B 2NVYB 1YNNC 5M5XB 3CQZB 1TWHB 1Y1WB 3HOZB 3GTGB 3GTOB 3I4NB 3HOXB 2WB1B 5M3MB 4A3JB 1I50B 2A69C 2WAQB 3K7AB 3RZOB 3GTJB 3S14B 2A68C 3GTPB 2R92B 4C2MB 1TWAB 3PO3B 2JA8B 3DXJC 3H3VC 4A3IB 2JA7B 5C44B 1HQMC 2R7ZB 2JA6B 4A3KB 2E2JB 3GTQB 1K83B 3S2DB 3S1MB 3PO2B 4G7ZC 1Y1VB 4C3IB 4KBMA 4A3EB 1I3QB 3S16B 4Y7NB 3GTMB 3HOWB 2E2IB 2E2HB 4AYBB 3RZDB 4G7OC 2PMZB 3S1QB 3S15B 5M5WB 1I6VC 2NVXB 1IW7C 4QIWB 4BBRB 3FKIB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EQL C;  4BY1 B;  2VUM B;  2JA5 B;  1TWF B;  2R93 B;  4BY7 B;  4C3J B;  5M5Y B;  3S17 B;  5M3F B;  3HKZ B;  3GTK B;  1I6H B;  3LTI A;  3S1R B;  3M3Y B;  3H0G B;  2O5J C;  4A3G B;  1WCM B;  1SMY C;  2BE5 C;  2CW0 C;  3M4O B;  1SFO B;  2NVT B;  5C4X B;  2NVQ B;  2B63 B;  4LK1 C;  4KBJ A;  4GZY C;  3HOY B;  3I4M B;  4A3D B;  1R9T B;  3GTL B;  1YNJ C;  1ZYR C;  3S2H B;  4A3F B;  4BBS B;  4G7H C;  3S1N B;  4A93 B;  1TWG B;  4A3M B;  3HOV B;  2PPB C;  1TWC B;  2O5I C;  3HOU B;  2Y0S B;  4C3H B;  4A3B B;  2A6H C;  5C3E B;  5C4J B;  4LJZ C;  2A6E C;  2YU9 B;  2NVY B;  1YNN C;  5M5X B;  3CQZ B;  1TWH B;  1Y1W B;  3HOZ B;  3GTG B;  3GTO B;  3I4N B;  3HOX B;  2WB1 B;  5M3M B;  4A3J B;  1I50 B;  2A69 C;  2WAQ B;  3K7A B;  3RZO B;  3GTJ B;  3S14 B;  2A68 C;  3GTP B;  2R92 B;  4C2M B;  1TWA B;  3PO3 B;  2JA8 B;  3DXJ C;  3H3V C;  4A3I B;  2JA7 B;  5C44 B;  1HQM C;  2R7Z B;  2JA6 B;  4A3K B;  2E2J B;  3GTQ B;  1K83 B;  3S2D B;  3S1M B;  3PO2 B;  4G7Z C;  1Y1V B;  4C3I B;  4KBM A;  4A3E B;  1I3Q B;  3S16 B;  4Y7N B;  3GTM B;  3HOW B;  2E2I B;  2E2H B;  4AYB B;  3RZD B;  4G7O C;  2PMZ B;  3S1Q B;  3S15 B;  5M5W B;  1I6V C;  2NVX B;  1IW7 C;  4QIW B;  4BBR B;  3FKI B; 
#chains in the Genus database with same CATH topology
 3EQL C;  4BY1 B;  2VUM B;  2JA5 B;  1TWF B;  2R93 B;  4BY7 B;  4C3J B;  5M5Y B;  3S17 B;  5M3F B;  3HKZ B;  3GTK B;  1I6H B;  3LTI A;  3S1R B;  3M3Y B;  3H0G B;  2O5J C;  4A3G B;  1WCM B;  1SMY C;  2BE5 C;  2CW0 C;  3M4O B;  1SFO B;  2NVT B;  5C4X B;  2NVQ B;  2B63 B;  4LK1 C;  4KBJ A;  4GZY C;  3HOY B;  3I4M B;  4A3D B;  1R9T B;  3GTL B;  1YNJ C;  1ZYR C;  3S2H B;  4A3F B;  4BBS B;  4G7H C;  3S1N B;  4A93 B;  1TWG B;  4A3M B;  3HOV B;  2PPB C;  1TWC B;  2O5I C;  3HOU B;  2Y0S B;  4C3H B;  4A3B B;  2A6H C;  5C3E B;  5C4J B;  4LJZ C;  2A6E C;  2YU9 B;  2NVY B;  1YNN C;  5M5X B;  3CQZ B;  1TWH B;  1Y1W B;  3HOZ B;  3GTG B;  3GTO B;  3I4N B;  3HOX B;  2WB1 B;  5M3M B;  4A3J B;  1I50 B;  2A69 C;  2WAQ B;  3K7A B;  3RZO B;  3GTJ B;  3S14 B;  2A68 C;  3GTP B;  2R92 B;  4C2M B;  1TWA B;  3PO3 B;  2JA8 B;  3DXJ C;  3H3V C;  4A3I B;  2JA7 B;  5C44 B;  1HQM C;  2R7Z B;  2JA6 B;  4A3K B;  2E2J B;  3GTQ B;  1K83 B;  3S2D B;  3S1M B;  3PO2 B;  4G7Z C;  1Y1V B;  4C3I B;  4KBM A;  4A3E B;  1I3Q B;  3S16 B;  4Y7N B;  3GTM B;  3HOW B;  2E2I B;  2E2H B;  4AYB B;  3RZD B;  4G7O C;  2PMZ B;  3S1Q B;  3S15 B;  5M5W B;  1I6V C;  2NVX B;  1IW7 C;  4QIW B;  4BBR B;  3FKI B; 
#chains in the Genus database with same CATH homology
 3EQL C;  4BY1 B;  2VUM B;  2JA5 B;  1TWF B;  2R93 B;  4BY7 B;  4C3J B;  5M5Y B;  3S17 B;  5M3F B;  3HKZ B;  3GTK B;  1I6H B;  3LTI A;  3S1R B;  3M3Y B;  3H0G B;  2O5J C;  4A3G B;  1WCM B;  1SMY C;  2BE5 C;  2CW0 C;  3M4O B;  1SFO B;  2NVT B;  5C4X B;  2NVQ B;  2B63 B;  4LK1 C;  4KBJ A;  4GZY C;  3HOY B;  3I4M B;  4A3D B;  1R9T B;  3GTL B;  1YNJ C;  1ZYR C;  3S2H B;  4A3F B;  4BBS B;  4G7H C;  3S1N B;  4A93 B;  1TWG B;  4A3M B;  3HOV B;  2PPB C;  1TWC B;  2O5I C;  3HOU B;  2Y0S B;  4C3H B;  4A3B B;  2A6H C;  5C3E B;  5C4J B;  4LJZ C;  2A6E C;  2YU9 B;  2NVY B;  1YNN C;  5M5X B;  3CQZ B;  1TWH B;  1Y1W B;  3HOZ B;  3GTG B;  3GTO B;  3I4N B;  3HOX B;  2WB1 B;  5M3M B;  4A3J B;  1I50 B;  2A69 C;  2WAQ B;  3K7A B;  3RZO B;  3GTJ B;  3S14 B;  2A68 C;  3GTP B;  2R92 B;  4C2M B;  1TWA B;  3PO3 B;  2JA8 B;  3DXJ C;  3H3V C;  4A3I B;  2JA7 B;  5C44 B;  1HQM C;  2R7Z B;  2JA6 B;  4A3K B;  2E2J B;  3GTQ B;  1K83 B;  3S2D B;  3S1M B;  3PO2 B;  4G7Z C;  1Y1V B;  4C3I B;  4KBM A;  4A3E B;  1I3Q B;  3S16 B;  4Y7N B;  3GTM B;  3HOW B;  2E2I B;  2E2H B;  4AYB B;  3RZD B;  4G7O C;  2PMZ B;  3S1Q B;  3S15 B;  5M5W B;  1I6V C;  2NVX B;  1IW7 C;  4QIW B;  4BBR B;  3FKI B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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