The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
119
|
sequence length |
386
|
structure length |
384
|
Chain Sequence |
PRGSHMMLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGEPITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFF
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structure of the Mtb CarD/RNAP beta-Lobes Complex Reveals the Molecular Basis of Interaction and Presents a Distinct DNA-Binding Domain for Mtb CarD.
pubmed doi rcsb |
| molecule keywords |
DNA-directed RNA polymerase subunit beta
|
| molecule tags |
Transferase
|
| source organism |
Mycobacterium tuberculosis
|
| total genus |
119
|
| structure length |
384
|
| sequence length |
386
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
2.7.7.6: DNA-directed RNA polymerase. |
| pdb deposition date | 2013-04-23 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF04561 | RNA_pol_Rpb2_2 | RNA polymerase Rpb2, domain 2 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Alpha-Beta Complex | Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 | RNA polymerase Rpb2, domain 2 |
#chains in the Genus database with same CATH superfamily 2E2H B; 1IW7 C; 4A3F B; 3HOZ B; 1K83 B; 5M5Y B; 2PMZ B; 2JA6 B; 1R9T B; 2JA7 B; 2NVQ B; 2A69 C; 1ZYR C; 4A3E B; 2R92 B; 5M5W B; 4A3D B; 1TWC B; 3HKZ B; 1I6V C; 4A93 B; 3RZO B; 3EQL C; 1I50 B; 3H0G B; 3HOU B; 3HOY B; 3GTM B; 1WCM B; 2NVY B; 3GTQ B; 2CW0 C; 4KBJ A; 3S16 B; 2JA5 B; 4A3G B; 1Y1V B; 4G7H C; 3FKI B; 3RZD B; 4C3J B; 3DXJ C; 3S1Q B; 1TWA B; 4G7O C; 2A68 C; 4LJZ C; 3S2H B; 3PO2 B; 2A6H C; 1HQM C; 4A3M B; 2WAQ B; 3S17 B; 4GZY C; 2VUM B; 2PPB C; 4LK1 C; 3GTO B; 1YNN C; 1SMY C; 2A6E C; 3S1N B; 3CQZ B; 5C4X B; 5M5X B; 5M3M B; 4C3H B; 4AYB B; 1TWG B; 4A3J B; 3PO3 B; 2BE5 C; 3S14 B; 2R7Z B; 4G7Z C; 2NVX B; 2E2J B; 5C44 B; 2O5I C; 3GTG B; 3K7A B; 1YNJ C; 3HOX B; 3S1M B; 3M3Y B; 2O5J C; 3GTP B; 4A3B B; 4BY1 B; 3GTK B; 3S2D B; 2WB1 B; 4C2M B; 4C3I B; 3GTL B; 3I4M B; 2JA8 B; 2Y0S B; 2NVT B; 5C4J B; 2YU9 B; 3S1R B; 3LTI A; 1TWF B; 1I3Q B; 1SFO B; 4BBS B; 4A3K B; 3HOV B; 2B63 B; 4Y7N B; 5M3F B; 3M4O B; 1I6H B; 2R93 B; 4BY7 B; 3S15 B; 3H3V C; 3GTJ B; 4KBM A; 2E2I B; 3I4N B; 1TWH B; 4QIW B; 3HOW B; 4A3I B; 1Y1W B; 4BBR B; 5C3E B; #chains in the Genus database with same CATH topology 2E2H B; 1IW7 C; 4A3F B; 3HOZ B; 1K83 B; 5M5Y B; 2PMZ B; 2JA6 B; 1R9T B; 2JA7 B; 2NVQ B; 2A69 C; 1ZYR C; 4A3E B; 2R92 B; 5M5W B; 4A3D B; 1TWC B; 3HKZ B; 1I6V C; 4A93 B; 3RZO B; 3EQL C; 1I50 B; 3H0G B; 3HOU B; 3HOY B; 3GTM B; 1WCM B; 2NVY B; 3GTQ B; 2CW0 C; 4KBJ A; 3S16 B; 2JA5 B; 4A3G B; 1Y1V B; 4G7H C; 3FKI B; 3RZD B; 4C3J B; 3DXJ C; 3S1Q B; 1TWA B; 4G7O C; 2A68 C; 4LJZ C; 3S2H B; 3PO2 B; 2A6H C; 1HQM C; 4A3M B; 2WAQ B; 3S17 B; 4GZY C; 2VUM B; 2PPB C; 4LK1 C; 3GTO B; 1YNN C; 1SMY C; 2A6E C; 3S1N B; 3CQZ B; 5C4X B; 5M5X B; 5M3M B; 4C3H B; 4AYB B; 1TWG B; 4A3J B; 3PO3 B; 2BE5 C; 3S14 B; 2R7Z B; 4G7Z C; 2NVX B; 2E2J B; 5C44 B; 2O5I C; 3GTG B; 3K7A B; 1YNJ C; 3HOX B; 3S1M B; 3M3Y B; 2O5J C; 3GTP B; 4A3B B; 4BY1 B; 3GTK B; 3S2D B; 2WB1 B; 4C2M B; 4C3I B; 3GTL B; 3I4M B; 2JA8 B; 2Y0S B; 2NVT B; 5C4J B; 2YU9 B; 3S1R B; 3LTI A; 1TWF B; 1I3Q B; 1SFO B; 4BBS B; 4A3K B; 3HOV B; 2B63 B; 4Y7N B; 5M3F B; 3M4O B; 1I6H B; 2R93 B; 4BY7 B; 3S15 B; 3H3V C; 3GTJ B; 4KBM A; 2E2I B; 3I4N B; 1TWH B; 4QIW B; 3HOW B; 4A3I B; 1Y1W B; 4BBR B; 5C3E B; #chains in the Genus database with same CATH homology 2E2H B; 1IW7 C; 4A3F B; 3HOZ B; 1K83 B; 5M5Y B; 2PMZ B; 2JA6 B; 1R9T B; 2JA7 B; 2NVQ B; 2A69 C; 1ZYR C; 4A3E B; 2R92 B; 5M5W B; 4A3D B; 1TWC B; 3HKZ B; 1I6V C; 4A93 B; 3RZO B; 3EQL C; 1I50 B; 3H0G B; 3HOU B; 3HOY B; 3GTM B; 1WCM B; 2NVY B; 3GTQ B; 2CW0 C; 4KBJ A; 3S16 B; 2JA5 B; 4A3G B; 1Y1V B; 4G7H C; 3FKI B; 3RZD B; 4C3J B; 3DXJ C; 3S1Q B; 1TWA B; 4G7O C; 2A68 C; 4LJZ C; 3S2H B; 3PO2 B; 2A6H C; 1HQM C; 4A3M B; 2WAQ B; 3S17 B; 4GZY C; 2VUM B; 2PPB C; 4LK1 C; 3GTO B; 1YNN C; 1SMY C; 2A6E C; 3S1N B; 3CQZ B; 5C4X B; 5M5X B; 5M3M B; 4C3H B; 4AYB B; 1TWG B; 4A3J B; 3PO3 B; 2BE5 C; 3S14 B; 2R7Z B; 4G7Z C; 2NVX B; 2E2J B; 5C44 B; 2O5I C; 3GTG B; 3K7A B; 1YNJ C; 3HOX B; 3S1M B; 3M3Y B; 2O5J C; 3GTP B; 4A3B B; 4BY1 B; 3GTK B; 3S2D B; 2WB1 B; 4C2M B; 4C3I B; 3GTL B; 3I4M B; 2JA8 B; 2Y0S B; 2NVT B; 5C4J B; 2YU9 B; 3S1R B; 3LTI A; 1TWF B; 1I3Q B; 1SFO B; 4BBS B; 4A3K B; 3HOV B; 2B63 B; 4Y7N B; 5M3F B; 3M4O B; 1I6H B; 2R93 B; 4BY7 B; 3S15 B; 3H3V C; 3GTJ B; 4KBM A; 2E2I B; 3I4N B; 1TWH B; 4QIW B; 3HOW B; 4A3I B; 1Y1W B; 4BBR B; 5C3E B;
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