4KBMA

Structure of the mtb card/rnap beta subunit b1-b2 domains complex
Total Genus 122
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
122
sequence length
386
structure length
386
Chain Sequence
RGSHMMLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGEPITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of the Mtb CarD/RNAP beta-Lobes Complex Reveals the Molecular Basis of Interaction and Presents a Distinct DNA-Binding Domain for Mtb CarD.
pubmed doi rcsb
molecule tags Transferase/transcription
source organism Mycobacterium tuberculosis
molecule keywords DNA-directed RNA polymerase subunit beta
total genus 122
structure length 386
sequence length 386
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2013-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04561 RNA_pol_Rpb2_2 RNA polymerase Rpb2, domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1110.10 Alpha Beta Alpha-Beta Complex Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 RNA polymerase Rpb2, domain 2 4kbmA02
2A6EC 5M5WB 4A3JB 4QIWB 3S16B 1K83B 3S1QB 2PMZB 2WB1B 3S14B 4A3DB 1I50B 3GTLB 3H3VC 1IW7C 2NVYB 3GTMB 1Y1WB 3RZOB 1ZYRC 4G7ZC 3S2HB 4BY1B 4A93B 3GTKB 2O5JC 4Y7NB 3HKZB 5C3EB 2VUMB 2PPBC 2A69C 4LJZC 3M3YB 3PO2B 5M3FB 2NVTB 4A3BB 1R9TB 3S15B 1TWHB 1Y1VB 3H0GB 1I6HB 1TWCB 4KBJA 4BBSB 2Y0SB 1I3QB 2JA7B 2WAQB 4A3KB 1I6VC 2E2HB 2NVQB 4A3GB 2JA8B 4GZYC 2NVXB 4A3EB 3S17B 4BBRB 4BY7B 3HOWB 2YU9B 3HOXB 3K7AB 3EQLC 3CQZB 2B63B 5C4JB 3GTOB 4C3HB 3GTJB 2E2JB 2A68C 3GTGB 5M3MB 4C2MB 3S1NB 3FKIB 4A3MB 5M5XB 5C4XB 3DXJC 1TWAB 3PO3B 3I4MB 4C3IB 1HQMC 4C3JB 2A6HC 3S1MB 3M4OB 1TWGB 3S2DB 3LTIA 2R92B 4KBMA 4G7OC 4G7HC 3HOZB 1TWFB 2CW0C 5C44B 2JA6B 3HOUB 4A3IB 3HOYB 4AYBB 3S1RB 3GTPB 1WCMB 4A3FB 2E2IB 2O5IC 3I4NB 1SFOB 4LK1C 1YNNC 2JA5B 3HOVB 3RZDB 5M5YB 1SMYC 2R7ZB 2BE5C 2R93B 1YNJC 3GTQB
chains in the Genus database with same CATH superfamily
2A6EC 5M5WB 4A3JB 4QIWB 3S16B 1K83B 3S1QB 2PMZB 2WB1B 3S14B 4A3DB 1I50B 3GTLB 3H3VC 1IW7C 2NVYB 3GTMB 1Y1WB 3RZOB 1ZYRC 4G7ZC 3S2HB 4BY1B 4A93B 3GTKB 2O5JC 4Y7NB 3HKZB 5C3EB 2VUMB 2PPBC 2A69C 4LJZC 3M3YB 3PO2B 5M3FB 2NVTB 4A3BB 1R9TB 3S15B 1TWHB 1Y1VB 3H0GB 1I6HB 1TWCB 4KBJA 4BBSB 2Y0SB 1I3QB 2JA7B 2WAQB 4A3KB 1I6VC 2E2HB 2NVQB 4A3GB 2JA8B 4GZYC 2NVXB 4A3EB 3S17B 4BBRB 4BY7B 3HOWB 2YU9B 3HOXB 3K7AB 3EQLC 3CQZB 2B63B 5C4JB 3GTOB 4C3HB 3GTJB 2E2JB 2A68C 3GTGB 5M3MB 4C2MB 3S1NB 3FKIB 4A3MB 5M5XB 5C4XB 3DXJC 1TWAB 3PO3B 3I4MB 4C3IB 1HQMC 4C3JB 2A6HC 3S1MB 3M4OB 1TWGB 3S2DB 3LTIA 2R92B 4KBMA 4G7OC 4G7HC 3HOZB 1TWFB 2CW0C 5C44B 2JA6B 3HOUB 4A3IB 3HOYB 4AYBB 3S1RB 3GTPB 1WCMB 4A3FB 2E2IB 2O5IC 3I4NB 1SFOB 4LK1C 1YNNC 2JA5B 3HOVB 3RZDB 5M5YB 1SMYC 2R7ZB 2BE5C 2R93B 1YNJC 3GTQB
chains in the Genus database with same CATH topology
2A6EC 5M5WB 4A3JB 4QIWB 3S16B 1K83B 3S1QB 2PMZB 2WB1B 3S14B 4A3DB 1I50B 3GTLB 3H3VC 1IW7C 2NVYB 3GTMB 1Y1WB 3RZOB 1ZYRC 4G7ZC 3S2HB 4BY1B 4A93B 3GTKB 2O5JC 4Y7NB 3HKZB 5C3EB 2VUMB 2PPBC 2A69C 4LJZC 3M3YB 3PO2B 5M3FB 2NVTB 4A3BB 1R9TB 3S15B 1TWHB 1Y1VB 3H0GB 1I6HB 1TWCB 4KBJA 4BBSB 2Y0SB 1I3QB 2JA7B 2WAQB 4A3KB 1I6VC 2E2HB 2NVQB 4A3GB 2JA8B 4GZYC 2NVXB 4A3EB 3S17B 4BBRB 4BY7B 3HOWB 2YU9B 3HOXB 3K7AB 3EQLC 3CQZB 2B63B 5C4JB 3GTOB 4C3HB 3GTJB 2E2JB 2A68C 3GTGB 5M3MB 4C2MB 3S1NB 3FKIB 4A3MB 5M5XB 5C4XB 3DXJC 1TWAB 3PO3B 3I4MB 4C3IB 1HQMC 4C3JB 2A6HC 3S1MB 3M4OB 1TWGB 3S2DB 3LTIA 2R92B 4KBMA 4G7OC 4G7HC 3HOZB 1TWFB 2CW0C 5C44B 2JA6B 3HOUB 4A3IB 3HOYB 4AYBB 3S1RB 3GTPB 1WCMB 4A3FB 2E2IB 2O5IC 3I4NB 1SFOB 4LK1C 1YNNC 2JA5B 3HOVB 3RZDB 5M5YB 1SMYC 2R7ZB 2BE5C 2R93B 1YNJC 3GTQB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A6E C;  5M5W B;  4A3J B;  4QIW B;  3S16 B;  1K83 B;  3S1Q B;  2PMZ B;  2WB1 B;  3S14 B;  4A3D B;  1I50 B;  3GTL B;  3H3V C;  1IW7 C;  2NVY B;  3GTM B;  1Y1W B;  3RZO B;  1ZYR C;  4G7Z C;  3S2H B;  4BY1 B;  4A93 B;  3GTK B;  2O5J C;  4Y7N B;  3HKZ B;  5C3E B;  2VUM B;  2PPB C;  2A69 C;  4LJZ C;  3M3Y B;  3PO2 B;  5M3F B;  2NVT B;  4A3B B;  1R9T B;  3S15 B;  1TWH B;  1Y1V B;  3H0G B;  1I6H B;  1TWC B;  4KBJ A;  4BBS B;  2Y0S B;  1I3Q B;  2JA7 B;  2WAQ B;  4A3K B;  1I6V C;  2E2H B;  2NVQ B;  4A3G B;  2JA8 B;  4GZY C;  2NVX B;  4A3E B;  3S17 B;  4BBR B;  4BY7 B;  3HOW B;  2YU9 B;  3HOX B;  3K7A B;  3EQL C;  3CQZ B;  2B63 B;  5C4J B;  3GTO B;  4C3H B;  3GTJ B;  2E2J B;  2A68 C;  3GTG B;  5M3M B;  4C2M B;  3S1N B;  3FKI B;  4A3M B;  5M5X B;  5C4X B;  3DXJ C;  1TWA B;  3PO3 B;  3I4M B;  4C3I B;  1HQM C;  4C3J B;  2A6H C;  3S1M B;  3M4O B;  1TWG B;  3S2D B;  3LTI A;  2R92 B;  4KBM A;  4G7O C;  4G7H C;  3HOZ B;  1TWF B;  2CW0 C;  5C44 B;  2JA6 B;  3HOU B;  4A3I B;  3HOY B;  4AYB B;  3S1R B;  3GTP B;  1WCM B;  4A3F B;  2E2I B;  2O5I C;  3I4N B;  1SFO B;  4LK1 C;  1YNN C;  2JA5 B;  3HOV B;  3RZD B;  5M5Y B;  1SMY C;  2R7Z B;  2BE5 C;  2R93 B;  1YNJ C;  3GTQ B; 
#chains in the Genus database with same CATH topology
 2A6E C;  5M5W B;  4A3J B;  4QIW B;  3S16 B;  1K83 B;  3S1Q B;  2PMZ B;  2WB1 B;  3S14 B;  4A3D B;  1I50 B;  3GTL B;  3H3V C;  1IW7 C;  2NVY B;  3GTM B;  1Y1W B;  3RZO B;  1ZYR C;  4G7Z C;  3S2H B;  4BY1 B;  4A93 B;  3GTK B;  2O5J C;  4Y7N B;  3HKZ B;  5C3E B;  2VUM B;  2PPB C;  2A69 C;  4LJZ C;  3M3Y B;  3PO2 B;  5M3F B;  2NVT B;  4A3B B;  1R9T B;  3S15 B;  1TWH B;  1Y1V B;  3H0G B;  1I6H B;  1TWC B;  4KBJ A;  4BBS B;  2Y0S B;  1I3Q B;  2JA7 B;  2WAQ B;  4A3K B;  1I6V C;  2E2H B;  2NVQ B;  4A3G B;  2JA8 B;  4GZY C;  2NVX B;  4A3E B;  3S17 B;  4BBR B;  4BY7 B;  3HOW B;  2YU9 B;  3HOX B;  3K7A B;  3EQL C;  3CQZ B;  2B63 B;  5C4J B;  3GTO B;  4C3H B;  3GTJ B;  2E2J B;  2A68 C;  3GTG B;  5M3M B;  4C2M B;  3S1N B;  3FKI B;  4A3M B;  5M5X B;  5C4X B;  3DXJ C;  1TWA B;  3PO3 B;  3I4M B;  4C3I B;  1HQM C;  4C3J B;  2A6H C;  3S1M B;  3M4O B;  1TWG B;  3S2D B;  3LTI A;  2R92 B;  4KBM A;  4G7O C;  4G7H C;  3HOZ B;  1TWF B;  2CW0 C;  5C44 B;  2JA6 B;  3HOU B;  4A3I B;  3HOY B;  4AYB B;  3S1R B;  3GTP B;  1WCM B;  4A3F B;  2E2I B;  2O5I C;  3I4N B;  1SFO B;  4LK1 C;  1YNN C;  2JA5 B;  3HOV B;  3RZD B;  5M5Y B;  1SMY C;  2R7Z B;  2BE5 C;  2R93 B;  1YNJ C;  3GTQ B; 
#chains in the Genus database with same CATH homology
 2A6E C;  5M5W B;  4A3J B;  4QIW B;  3S16 B;  1K83 B;  3S1Q B;  2PMZ B;  2WB1 B;  3S14 B;  4A3D B;  1I50 B;  3GTL B;  3H3V C;  1IW7 C;  2NVY B;  3GTM B;  1Y1W B;  3RZO B;  1ZYR C;  4G7Z C;  3S2H B;  4BY1 B;  4A93 B;  3GTK B;  2O5J C;  4Y7N B;  3HKZ B;  5C3E B;  2VUM B;  2PPB C;  2A69 C;  4LJZ C;  3M3Y B;  3PO2 B;  5M3F B;  2NVT B;  4A3B B;  1R9T B;  3S15 B;  1TWH B;  1Y1V B;  3H0G B;  1I6H B;  1TWC B;  4KBJ A;  4BBS B;  2Y0S B;  1I3Q B;  2JA7 B;  2WAQ B;  4A3K B;  1I6V C;  2E2H B;  2NVQ B;  4A3G B;  2JA8 B;  4GZY C;  2NVX B;  4A3E B;  3S17 B;  4BBR B;  4BY7 B;  3HOW B;  2YU9 B;  3HOX B;  3K7A B;  3EQL C;  3CQZ B;  2B63 B;  5C4J B;  3GTO B;  4C3H B;  3GTJ B;  2E2J B;  2A68 C;  3GTG B;  5M3M B;  4C2M B;  3S1N B;  3FKI B;  4A3M B;  5M5X B;  5C4X B;  3DXJ C;  1TWA B;  3PO3 B;  3I4M B;  4C3I B;  1HQM C;  4C3J B;  2A6H C;  3S1M B;  3M4O B;  1TWG B;  3S2D B;  3LTI A;  2R92 B;  4KBM A;  4G7O C;  4G7H C;  3HOZ B;  1TWF B;  2CW0 C;  5C44 B;  2JA6 B;  3HOU B;  4A3I B;  3HOY B;  4AYB B;  3S1R B;  3GTP B;  1WCM B;  4A3F B;  2E2I B;  2O5I C;  3I4N B;  1SFO B;  4LK1 C;  1YNN C;  2JA5 B;  3HOV B;  3RZD B;  5M5Y B;  1SMY C;  2R7Z B;  2BE5 C;  2R93 B;  1YNJ C;  3GTQ B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...