4KBMA

Structure of the mtb card/rnap beta subunit b1-b2 domains complex
Total Genus 122
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
122
sequence length
386
structure length
386
Chain Sequence
RGSHMMLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGEPITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of the Mtb CarD/RNAP beta-Lobes Complex Reveals the Molecular Basis of Interaction and Presents a Distinct DNA-Binding Domain for Mtb CarD.
pubmed doi rcsb
molecule tags Transferase/transcription
source organism Mycobacterium tuberculosis
molecule keywords DNA-directed RNA polymerase subunit beta
total genus 122
structure length 386
sequence length 386
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2013-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04561 RNA_pol_Rpb2_2 RNA polymerase Rpb2, domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1110.10 Alpha Beta Alpha-Beta Complex Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 RNA polymerase Rpb2, domain 2 4kbmA02
2NVQB 5C3EB 2A6HC 1IW7C 5C44B 4Y7NB 1R9TB 4A3EB 4A3JB 2A69C 3LTIA 3H3VC 3HOXB 4LK1C 4BY1B 2E2IB 5M5YB 3S2DB 5M3FB 4A3IB 3RZDB 4A3BB 4KBJA 2JA5B 2R92B 2PPBC 3GTLB 3S16B 1Y1VB 1HQMC 1YNNC 1TWCB 2E2JB 4BY7B 3I4NB 4G7ZC 2WAQB 1TWHB 3S1QB 1Y1WB 2O5IC 2Y0SB 3S1NB 2BE5C 3CQZB 2R7ZB 2VUMB 1I6HB 3EQLC 5C4XB 3K7AB 2R93B 3I4MB 4C3IB 2B63B 3HOUB 3FKIB 4G7OC 1TWAB 3GTOB 2A68C 3HKZB 5M5WB 3M4OB 3DXJC 4QIWB 4A3DB 3PO2B 2A6EC 3S17B 2YU9B 4C2MB 1SFOB 4LJZC 5M3MB 4AYBB 3HOWB 2NVYB 1K83B 2NVTB 3RZOB 3S1MB 4A3GB 3S2HB 4KBMA 4BBRB 1I50B 5C4JB 4GZYC 4BBSB 2NVXB 2O5JC 1YNJC 2CW0C 4A93B 2WB1B 4C3HB 3GTJB 3HOYB 3GTKB 4A3KB 3H0GB 3GTGB 1SMYC 1TWFB 3HOVB 4G7HC 3S1RB 3S15B 1ZYRC 5M5XB 2E2HB 4A3MB 3GTQB 3M3YB 1WCMB 1TWGB 1I3QB 1I6VC 2JA6B 4A3FB 3S14B 3GTMB 2JA7B 4C3JB 3HOZB 2JA8B 3GTPB 3PO3B 2PMZB
chains in the Genus database with same CATH superfamily
2NVQB 5C3EB 2A6HC 1IW7C 5C44B 4Y7NB 1R9TB 4A3EB 4A3JB 2A69C 3LTIA 3H3VC 3HOXB 4LK1C 4BY1B 2E2IB 5M5YB 3S2DB 5M3FB 4A3IB 3RZDB 4A3BB 4KBJA 2JA5B 2R92B 2PPBC 3GTLB 3S16B 1Y1VB 1HQMC 1YNNC 1TWCB 2E2JB 4BY7B 3I4NB 4G7ZC 2WAQB 1TWHB 3S1QB 1Y1WB 2O5IC 2Y0SB 3S1NB 2BE5C 3CQZB 2R7ZB 2VUMB 1I6HB 3EQLC 5C4XB 3K7AB 2R93B 3I4MB 4C3IB 2B63B 3HOUB 3FKIB 4G7OC 1TWAB 3GTOB 2A68C 3HKZB 5M5WB 3M4OB 3DXJC 4QIWB 4A3DB 3PO2B 2A6EC 3S17B 2YU9B 4C2MB 1SFOB 4LJZC 5M3MB 4AYBB 3HOWB 2NVYB 1K83B 2NVTB 3RZOB 3S1MB 4A3GB 3S2HB 4KBMA 4BBRB 1I50B 5C4JB 4GZYC 4BBSB 2NVXB 2O5JC 1YNJC 2CW0C 4A93B 2WB1B 4C3HB 3GTJB 3HOYB 3GTKB 4A3KB 3H0GB 3GTGB 1SMYC 1TWFB 3HOVB 4G7HC 3S1RB 3S15B 1ZYRC 5M5XB 2E2HB 4A3MB 3GTQB 3M3YB 1WCMB 1TWGB 1I3QB 1I6VC 2JA6B 4A3FB 3S14B 3GTMB 2JA7B 4C3JB 3HOZB 2JA8B 3GTPB 3PO3B 2PMZB
chains in the Genus database with same CATH topology
2NVQB 5C3EB 2A6HC 1IW7C 5C44B 4Y7NB 1R9TB 4A3EB 4A3JB 2A69C 3LTIA 3H3VC 3HOXB 4LK1C 4BY1B 2E2IB 5M5YB 3S2DB 5M3FB 4A3IB 3RZDB 4A3BB 4KBJA 2JA5B 2R92B 2PPBC 3GTLB 3S16B 1Y1VB 1HQMC 1YNNC 1TWCB 2E2JB 4BY7B 3I4NB 4G7ZC 2WAQB 1TWHB 3S1QB 1Y1WB 2O5IC 2Y0SB 3S1NB 2BE5C 3CQZB 2R7ZB 2VUMB 1I6HB 3EQLC 5C4XB 3K7AB 2R93B 3I4MB 4C3IB 2B63B 3HOUB 3FKIB 4G7OC 1TWAB 3GTOB 2A68C 3HKZB 5M5WB 3M4OB 3DXJC 4QIWB 4A3DB 3PO2B 2A6EC 3S17B 2YU9B 4C2MB 1SFOB 4LJZC 5M3MB 4AYBB 3HOWB 2NVYB 1K83B 2NVTB 3RZOB 3S1MB 4A3GB 3S2HB 4KBMA 4BBRB 1I50B 5C4JB 4GZYC 4BBSB 2NVXB 2O5JC 1YNJC 2CW0C 4A93B 2WB1B 4C3HB 3GTJB 3HOYB 3GTKB 4A3KB 3H0GB 3GTGB 1SMYC 1TWFB 3HOVB 4G7HC 3S1RB 3S15B 1ZYRC 5M5XB 2E2HB 4A3MB 3GTQB 3M3YB 1WCMB 1TWGB 1I3QB 1I6VC 2JA6B 4A3FB 3S14B 3GTMB 2JA7B 4C3JB 3HOZB 2JA8B 3GTPB 3PO3B 2PMZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVQ B;  5C3E B;  2A6H C;  1IW7 C;  5C44 B;  4Y7N B;  1R9T B;  4A3E B;  4A3J B;  2A69 C;  3LTI A;  3H3V C;  3HOX B;  4LK1 C;  4BY1 B;  2E2I B;  5M5Y B;  3S2D B;  5M3F B;  4A3I B;  3RZD B;  4A3B B;  4KBJ A;  2JA5 B;  2R92 B;  2PPB C;  3GTL B;  3S16 B;  1Y1V B;  1HQM C;  1YNN C;  1TWC B;  2E2J B;  4BY7 B;  3I4N B;  4G7Z C;  2WAQ B;  1TWH B;  3S1Q B;  1Y1W B;  2O5I C;  2Y0S B;  3S1N B;  2BE5 C;  3CQZ B;  2R7Z B;  2VUM B;  1I6H B;  3EQL C;  5C4X B;  3K7A B;  2R93 B;  3I4M B;  4C3I B;  2B63 B;  3HOU B;  3FKI B;  4G7O C;  1TWA B;  3GTO B;  2A68 C;  3HKZ B;  5M5W B;  3M4O B;  3DXJ C;  4QIW B;  4A3D B;  3PO2 B;  2A6E C;  3S17 B;  2YU9 B;  4C2M B;  1SFO B;  4LJZ C;  5M3M B;  4AYB B;  3HOW B;  2NVY B;  1K83 B;  2NVT B;  3RZO B;  3S1M B;  4A3G B;  3S2H B;  4KBM A;  4BBR B;  1I50 B;  5C4J B;  4GZY C;  4BBS B;  2NVX B;  2O5J C;  1YNJ C;  2CW0 C;  4A93 B;  2WB1 B;  4C3H B;  3GTJ B;  3HOY B;  3GTK B;  4A3K B;  3H0G B;  3GTG B;  1SMY C;  1TWF B;  3HOV B;  4G7H C;  3S1R B;  3S15 B;  1ZYR C;  5M5X B;  2E2H B;  4A3M B;  3GTQ B;  3M3Y B;  1WCM B;  1TWG B;  1I3Q B;  1I6V C;  2JA6 B;  4A3F B;  3S14 B;  3GTM B;  2JA7 B;  4C3J B;  3HOZ B;  2JA8 B;  3GTP B;  3PO3 B;  2PMZ B; 
#chains in the Genus database with same CATH topology
 2NVQ B;  5C3E B;  2A6H C;  1IW7 C;  5C44 B;  4Y7N B;  1R9T B;  4A3E B;  4A3J B;  2A69 C;  3LTI A;  3H3V C;  3HOX B;  4LK1 C;  4BY1 B;  2E2I B;  5M5Y B;  3S2D B;  5M3F B;  4A3I B;  3RZD B;  4A3B B;  4KBJ A;  2JA5 B;  2R92 B;  2PPB C;  3GTL B;  3S16 B;  1Y1V B;  1HQM C;  1YNN C;  1TWC B;  2E2J B;  4BY7 B;  3I4N B;  4G7Z C;  2WAQ B;  1TWH B;  3S1Q B;  1Y1W B;  2O5I C;  2Y0S B;  3S1N B;  2BE5 C;  3CQZ B;  2R7Z B;  2VUM B;  1I6H B;  3EQL C;  5C4X B;  3K7A B;  2R93 B;  3I4M B;  4C3I B;  2B63 B;  3HOU B;  3FKI B;  4G7O C;  1TWA B;  3GTO B;  2A68 C;  3HKZ B;  5M5W B;  3M4O B;  3DXJ C;  4QIW B;  4A3D B;  3PO2 B;  2A6E C;  3S17 B;  2YU9 B;  4C2M B;  1SFO B;  4LJZ C;  5M3M B;  4AYB B;  3HOW B;  2NVY B;  1K83 B;  2NVT B;  3RZO B;  3S1M B;  4A3G B;  3S2H B;  4KBM A;  4BBR B;  1I50 B;  5C4J B;  4GZY C;  4BBS B;  2NVX B;  2O5J C;  1YNJ C;  2CW0 C;  4A93 B;  2WB1 B;  4C3H B;  3GTJ B;  3HOY B;  3GTK B;  4A3K B;  3H0G B;  3GTG B;  1SMY C;  1TWF B;  3HOV B;  4G7H C;  3S1R B;  3S15 B;  1ZYR C;  5M5X B;  2E2H B;  4A3M B;  3GTQ B;  3M3Y B;  1WCM B;  1TWG B;  1I3Q B;  1I6V C;  2JA6 B;  4A3F B;  3S14 B;  3GTM B;  2JA7 B;  4C3J B;  3HOZ B;  2JA8 B;  3GTP B;  3PO3 B;  2PMZ B; 
#chains in the Genus database with same CATH homology
 2NVQ B;  5C3E B;  2A6H C;  1IW7 C;  5C44 B;  4Y7N B;  1R9T B;  4A3E B;  4A3J B;  2A69 C;  3LTI A;  3H3V C;  3HOX B;  4LK1 C;  4BY1 B;  2E2I B;  5M5Y B;  3S2D B;  5M3F B;  4A3I B;  3RZD B;  4A3B B;  4KBJ A;  2JA5 B;  2R92 B;  2PPB C;  3GTL B;  3S16 B;  1Y1V B;  1HQM C;  1YNN C;  1TWC B;  2E2J B;  4BY7 B;  3I4N B;  4G7Z C;  2WAQ B;  1TWH B;  3S1Q B;  1Y1W B;  2O5I C;  2Y0S B;  3S1N B;  2BE5 C;  3CQZ B;  2R7Z B;  2VUM B;  1I6H B;  3EQL C;  5C4X B;  3K7A B;  2R93 B;  3I4M B;  4C3I B;  2B63 B;  3HOU B;  3FKI B;  4G7O C;  1TWA B;  3GTO B;  2A68 C;  3HKZ B;  5M5W B;  3M4O B;  3DXJ C;  4QIW B;  4A3D B;  3PO2 B;  2A6E C;  3S17 B;  2YU9 B;  4C2M B;  1SFO B;  4LJZ C;  5M3M B;  4AYB B;  3HOW B;  2NVY B;  1K83 B;  2NVT B;  3RZO B;  3S1M B;  4A3G B;  3S2H B;  4KBM A;  4BBR B;  1I50 B;  5C4J B;  4GZY C;  4BBS B;  2NVX B;  2O5J C;  1YNJ C;  2CW0 C;  4A93 B;  2WB1 B;  4C3H B;  3GTJ B;  3HOY B;  3GTK B;  4A3K B;  3H0G B;  3GTG B;  1SMY C;  1TWF B;  3HOV B;  4G7H C;  3S1R B;  3S15 B;  1ZYR C;  5M5X B;  2E2H B;  4A3M B;  3GTQ B;  3M3Y B;  1WCM B;  1TWG B;  1I3Q B;  1I6V C;  2JA6 B;  4A3F B;  3S14 B;  3GTM B;  2JA7 B;  4C3J B;  3HOZ B;  2JA8 B;  3GTP B;  3PO3 B;  2PMZ B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...