4M8QC

Ontogeny of recognition specificity and functionality for the anti-hiv neutralizing antibody 4e10
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
148
structure length
148
Chain Sequence
HFRRHYVRHLPKEVSQNDIIKALASPLINDGMVVSDFADHVITREQNFPTGLPVEPVGVAIPHTDSKYVRQNAISVGILAEPVNFEDAGGEPDPVPVRVVFMLALGNWFDITNVLWWIMDVIQDEDFMQQLLVMNDDEIYQSIYTRIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords GEP1 Fv heavy chain
total genus 33
structure length 148
sequence length 148
chains with identical sequence S
ec nomenclature
pdb deposition date 2013-08-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.930.10 Alpha Beta 3-Layer(aba) Sandwich Mannitol-specific EII; Chain A Mannitol-specific EII; Chain A 4m8qC00
1A3AA 1XIZA 4ODXX 3BJVA 3OXPA 2A0JA 1J6TA 2OQTA 1A6JA 2OQ3A 3T43A 2FEWA 4GQXA 1HYNP 4KY9A 3LF6A 3URRA 4M8QC 4M62S
chains in the Genus database with same CATH superfamily
1A3AA 1XIZA 4ODXX 3BJVA 3OXPA 2A0JA 1J6TA 2OQTA 1A6JA 2OQ3A 3T43A 2FEWA 4GQXA 1HYNP 4KY9A 3LF6A 3URRA 4M8QC 4M62S
chains in the Genus database with same CATH topology
1A3AA 1XIZA 4ODXX 3BJVA 3OXPA 2A0JA 1J6TA 2OQTA 1A6JA 2OQ3A 3T43A 2FEWA 4GQXA 1HYNP 4KY9A 3LF6A 3URRA 4M8QC 4M62S
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A3A A;  1XIZ A;  4ODX X;  3BJV A;  3OXP A;  2A0J A;  1J6T A;  2OQT A;  1A6J A;  2OQ3 A;  3T43 A;  2FEW A;  4GQX A;  1HYN P;  4KY9 A;  3LF6 A;  3URR A;  4M8Q C;  4M62 S; 
#chains in the Genus database with same CATH topology
 1A3A A;  1XIZ A;  4ODX X;  3BJV A;  3OXP A;  2A0J A;  1J6T A;  2OQT A;  1A6J A;  2OQ3 A;  3T43 A;  2FEW A;  4GQX A;  1HYN P;  4KY9 A;  3LF6 A;  3URR A;  4M8Q C;  4M62 S; 
#chains in the Genus database with same CATH homology
 1A3A A;  1XIZ A;  4ODX X;  3BJV A;  3OXP A;  2A0J A;  1J6T A;  2OQT A;  1A6J A;  2OQ3 A;  3T43 A;  2FEW A;  4GQX A;  1HYN P;  4KY9 A;  3LF6 A;  3URR A;  4M8Q C;  4M62 S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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