4M8QC

Ontogeny of recognition specificity and functionality for the anti-hiv neutralizing antibody 4e10
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
148
structure length
148
Chain Sequence
HFRRHYVRHLPKEVSQNDIIKALASPLINDGMVVSDFADHVITREQNFPTGLPVEPVGVAIPHTDSKYVRQNAISVGILAEPVNFEDAGGEPDPVPVRVVFMLALGNWFDITNVLWWIMDVIQDEDFMQQLLVMNDDEIYQSIYTRIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords GEP1 Fv heavy chain
total genus 33
structure length 148
sequence length 148
chains with identical sequence S
ec nomenclature
pdb deposition date 2013-08-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.930.10 Alpha Beta 3-Layer(aba) Sandwich Mannitol-specific EII; Chain A Mannitol-specific EII; Chain A 4m8qC00
3BJVA 2OQTA 2FEWA 2OQ3A 1A3AA 4M62S 4ODXX 3OXPA 1HYNP 3URRA 1XIZA 4M8QC 2A0JA 3T43A 4GQXA 1A6JA 1J6TA 3LF6A 4KY9A
chains in the Genus database with same CATH superfamily
3BJVA 2OQTA 2FEWA 2OQ3A 1A3AA 4M62S 4ODXX 3OXPA 1HYNP 3URRA 1XIZA 4M8QC 2A0JA 3T43A 4GQXA 1A6JA 1J6TA 3LF6A 4KY9A
chains in the Genus database with same CATH topology
3BJVA 2OQTA 2FEWA 2OQ3A 1A3AA 4M62S 4ODXX 3OXPA 1HYNP 3URRA 1XIZA 4M8QC 2A0JA 3T43A 4GQXA 1A6JA 1J6TA 3LF6A 4KY9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BJV A;  2OQT A;  2FEW A;  2OQ3 A;  1A3A A;  4M62 S;  4ODX X;  3OXP A;  1HYN P;  3URR A;  1XIZ A;  4M8Q C;  2A0J A;  3T43 A;  4GQX A;  1A6J A;  1J6T A;  3LF6 A;  4KY9 A; 
#chains in the Genus database with same CATH topology
 3BJV A;  2OQT A;  2FEW A;  2OQ3 A;  1A3A A;  4M62 S;  4ODX X;  3OXP A;  1HYN P;  3URR A;  1XIZ A;  4M8Q C;  2A0J A;  3T43 A;  4GQX A;  1A6J A;  1J6T A;  3LF6 A;  4KY9 A; 
#chains in the Genus database with same CATH homology
 3BJV A;  2OQT A;  2FEW A;  2OQ3 A;  1A3A A;  4M62 S;  4ODX X;  3OXP A;  1HYN P;  3URR A;  1XIZ A;  4M8Q C;  2A0J A;  3T43 A;  4GQX A;  1A6J A;  1J6T A;  3LF6 A;  4KY9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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