4ODXX

4e10 germline encoded precursor no.7 in complex with epitope scaffold t117
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
152
structure length
152
Chain Sequence
MQGIHFRRHYVRHLPKEVSQNDIIKALASPLINDGMVVSDFADHVITREQNFPTGLPVEPVGVAIPHTDSKYVRQNAISVGILAEPVNFEDAGGEPDPVPVRVVFMLALGNWFDITNVLWWIMDVIQDEDFMQQLLVMNDDEIYQSIYTRIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
pubmed doi rcsb
molecule keywords 4E10 epitope scaffold T117
molecule tags Immune system
source organism Artificial gene
total genus 38
structure length 152
sequence length 152
chains with identical sequence Y
ec nomenclature
pdb deposition date 2014-01-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.930.10 Alpha Beta 3-Layer(aba) Sandwich Mannitol-specific EII; Chain A Mannitol-specific EII; Chain A 4odxX00
3T43A 4M62S 3OXPA 1HYNP 3LF6A 1A6JA 4ODXX 1J6TA 4GQXA 2A0JA 2OQTA 3BJVA 1XIZA 2OQ3A 2FEWA 4M8QC 4KY9A 1A3AA 3URRA
chains in the Genus database with same CATH superfamily
3T43A 4M62S 3OXPA 1HYNP 3LF6A 1A6JA 4ODXX 1J6TA 4GQXA 2A0JA 2OQTA 3BJVA 1XIZA 2OQ3A 2FEWA 4M8QC 4KY9A 1A3AA 3URRA
chains in the Genus database with same CATH topology
3T43A 4M62S 3OXPA 1HYNP 3LF6A 1A6JA 4ODXX 1J6TA 4GQXA 2A0JA 2OQTA 3BJVA 1XIZA 2OQ3A 2FEWA 4M8QC 4KY9A 1A3AA 3URRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T43 A;  4M62 S;  3OXP A;  1HYN P;  3LF6 A;  1A6J A;  4ODX X;  1J6T A;  4GQX A;  2A0J A;  2OQT A;  3BJV A;  1XIZ A;  2OQ3 A;  2FEW A;  4M8Q C;  4KY9 A;  1A3A A;  3URR A; 
#chains in the Genus database with same CATH topology
 3T43 A;  4M62 S;  3OXP A;  1HYN P;  3LF6 A;  1A6J A;  4ODX X;  1J6T A;  4GQX A;  2A0J A;  2OQT A;  3BJV A;  1XIZ A;  2OQ3 A;  2FEW A;  4M8Q C;  4KY9 A;  1A3A A;  3URR A; 
#chains in the Genus database with same CATH homology
 3T43 A;  4M62 S;  3OXP A;  1HYN P;  3LF6 A;  1A6J A;  4ODX X;  1J6T A;  4GQX A;  2A0J A;  2OQT A;  3BJV A;  1XIZ A;  2OQ3 A;  2FEW A;  4M8Q C;  4KY9 A;  1A3A A;  3URR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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