5HPT | Genus

Total Genus 39

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	39
sequence length	151
structure length	151
Chain Sequence	AASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRP

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__000758611839548__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__000758611839548__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/5hpt/C/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__000758611839548__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"000758611839548","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/5hpt/C/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__000758611839548__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Ligase/transferase
source organism	Homo sapiens
publication title	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. pubmed doi rcsb
molecule keywords	NEDD4-like E3 ubiquitin-protein ligase WWP1
total genus	39
structure length	151
sequence length	151
chains with identical sequence	F
ec nomenclature	ec 2.3.2.23: E2 ubiquitin-conjugating enzyme.
pdb deposition date	2016-01-20

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
C	PF00179	UQ_con	Ubiquitin-conjugating enzyme

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.110.10	Alpha Beta	Roll	Ubiquitin Conjugating Enzyme	Ubiquitin Conjugating Enzyme	5hptC00

1Z5SA 3HCTB 4DHZF 4P5OG 5IFRA 1A3SA 3TGDA 5F6UA 4YC1A 3JW0A 1X23A 4LDTC 3OBXA 3RPGA 4R62A 2A4DA 1WZVA 2PX9B 2Z6PA 2PWQA 2ESQA 1U9AA 3SY2C 4LADA 3P9HA 1JBBA 4QPLB 1JATA 2A7LA 1JATB 2C4PA 2DAXA 2Y9PA 1JASA 2NVUC 2ONUA 1QCQA 3ONGB 5HPTC 4DDGA 2O25A 1Z3DA 4NRGA 5EGGA 4NRGB 4DDIA 4L83A 1S1QA 2PE6A 5AIEB 4DHID 1ZGUA 2DAWA 2AAKA 4ZNYA 5D0KA 3CEGA 3EVXA 1WZWA 1ZUOA 3F92A 5F6XA 3UIPA 1KPSA 2GMIB 3OBSA 4Q5EC 2FUHA 4Y1LC 2MT6A 1U9BA 3WE5A 4CCGA 2CLWA 5D1MA 2BF8A 2CLWB 1Y6LA 3K9OA 2OXQA 2YB6A 1YH2A 2GRPA 3FN1B 3PTFA 2F0RA 3UIOA 3E95C 1KPPA 2QGXA 3UINA 5F6VA 1PZVA 5DFLA 4EJEA 5F6EA 3OBUA 3UGBA 2HLWA 2Y4WA 2Y9MA 2R0JA 4A4BC 5FERB 4V3KA 2ESOA 2GRNA 3O2UA 2K07A 4BWFA 4YIIU 5JNEB 1M4PA 5FQ2A 5F6DA 2GRRA 3R42A 1FBVC 5KNLC 2AWFA 4ONLA 4ONLB 4A49B 2GRQA 1Z2UA 2GMIA 2LXPA 2OB4A 3VONC 4TKPA 2H2YA 2Q0VA 1J7DB 1ZDNA 2GJDA 3FSHA 4DS2A 4MDKA 3JVZA 1TTEA 2EKEA 1Y8XA 2ESPA 4NR3B 5F6WA 4AUQA 1FXTA 2Z5DA 1YF9A 2CYXA 2EBMA 2DMFA 1C4ZD 2EBKA 2KLYA 3A4SA 4FH1A 4II2C 4Q5HC 3EB6B 4X57A 5D0MA 1W4UA 4Y1LA 3BZHA 3K9PA 3OBQA 4JUEA 4DHJC 1Q34A 2UYZA 1UZXA 1UKXA 4V3LA 3OJ4A 3L1YA 4ONMA 3R3QA 4ONMB 4S3OA 3E95A 2YBFA 1I7KA 4A4CC 4GPRA 4W5VA 2DAYA 2XWUA 3SQVC 2YHOB 2FO3A 1KPQA 2UCZA 2YZ0A 2GROA 1J74A 2EDIA 4NRIA 4NRIB 5AITB 5AIUB 1YLAA 5D1KA 3ZNIC 4AP4B 1J7DA 3P9GA 3W31B 1YRVA 2KJHA 2O25C 4WZ3A 2F4ZA 5F6YA 4NR3A 5D2MA 1AYZA 3L1ZA 2Z6OA 2AYVA 3E46A 4M1NA 3VONB 2BEPA 3H8KA 2F4WA 2C2VC 2VRRA 3A33A 2E2CA 4BVUB 5AITD 5D1LA 4IP3B 2ESKA 4JQUA 3RCZB 1M4QA 3RZ3A 2C2VB 3HCUB 1FZYA 4ONNA 3ZQSA 4ONNB 3KPAA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1Z5S A;  3HCT B;  4DHZ F;  4P5O G;  5IFR A;  1A3S A;  3TGD A;  5F6U A;  4YC1 A;  3JW0 A;  1X23 A;  4LDT C;  3OBX A;  3RPG A;  4R62 A;  2A4D A;  1WZV A;  2PX9 B;  2Z6P A;  2PWQ A;  2ESQ A;  1U9A A;  3SY2 C;  4LAD A;  3P9H A;  1JBB A;  4QPL B;  1JAT A;  2A7L A;  1JAT B;  2C4P A;  2DAX A;  2Y9P A;  1JAS A;  2NVU C;  2ONU A;  1QCQ A;  3ONG B;  5HPT C;  4DDG A;  2O25 A;  1Z3D A;  4NRG A;  5EGG A;  4NRG B;  4DDI A;  4L83 A;  1S1Q A;  2PE6 A;  5AIE B;  4DHI D;  1ZGU A;  2DAW A;  2AAK A;  4ZNY A;  5D0K A;  3CEG A;  3EVX A;  1WZW A;  1ZUO A;  3F92 A;  5F6X A;  3UIP A;  1KPS A;  2GMI B;  3OBS A;  4Q5E C;  2FUH A;  4Y1L C;  2MT6 A;  1U9B A;  3WE5 A;  4CCG A;  2CLW A;  5D1M A;  2BF8 A;  2CLW B;  1Y6L A;  3K9O A;  2OXQ A;  2YB6 A;  1YH2 A;  2GRP A;  3FN1 B;  3PTF A;  2F0R A;  3UIO A;  3E95 C;  1KPP A;  2QGX A;  3UIN A;  5F6V A;  1PZV A;  5DFL A;  4EJE A;  5F6E A;  3OBU A;  3UGB A;  2HLW A;  2Y4W A;  2Y9M A;  2R0J A;  4A4B C;  5FER B;  4V3K A;  2ESO A;  2GRN A;  3O2U A;  2K07 A;  4BWF A;  4YII U;  5JNE B;  1M4P A;  5FQ2 A;  5F6D A;  2GRR A;  3R42 A;  1FBV C;  5KNL C;  2AWF A;  4ONL A;  4ONL B;  4A49 B;  2GRQ A;  1Z2U A;  2GMI A;  2LXP A;  2OB4 A;  3VON C;  4TKP A;  2H2Y A;  2Q0V A;  1J7D B;  1ZDN A;  2GJD A;  3FSH A;  4DS2 A;  4MDK A;  3JVZ A;  1TTE A;  2EKE A;  1Y8X A;  2ESP A;  4NR3 B;  5F6W A;  4AUQ A;  1FXT A;  2Z5D A;  1YF9 A;  2CYX A;  2EBM A;  2DMF A;  1C4Z D;  2EBK A;  2KLY A;  3A4S A;  4FH1 A;  4II2 C;  4Q5H C;  3EB6 B;  4X57 A;  5D0M A;  1W4U A;  4Y1L A;  3BZH A;  3K9P A;  3OBQ A;  4JUE A;  4DHJ C;  1Q34 A;  2UYZ A;  1UZX A;  1UKX A;  4V3L A;  3OJ4 A;  3L1Y A;  4ONM A;  3R3Q A;  4ONM B;  4S3O A;  3E95 A;  2YBF A;  1I7K A;  4A4C C;  4GPR A;  4W5V A;  2DAY A;  2XWU A;  3SQV C;  2YHO B;  2FO3 A;  1KPQ A;  2UCZ A;  2YZ0 A;  2GRO A;  1J74 A;  2EDI A;  4NRI A;  4NRI B;  5AIT B;  5AIU B;  1YLA A;  5D1K A;  3ZNI C;  4AP4 B;  1J7D A;  3P9G A;  3W31 B;  1YRV A;  2KJH A;  2O25 C;  4WZ3 A;  2F4Z A;  5F6Y A;  4NR3 A;  5D2M A;  1AYZ A;  3L1Z A;  2Z6O A;  2AYV A;  3E46 A;  4M1N A;  3VON B;  2BEP A;  3H8K A;  2F4W A;  2C2V C;  2VRR A;  3A33 A;  2E2C A;  4BVU B;  5AIT D;  5D1L A;  4IP3 B;  2ESK A;  4JQU A;  3RCZ B;  1M4Q A;  3RZ3 A;  2C2V B;  3HCU B;  1FZY A;  4ONN A;  3ZQS A;  4ONN B;  3KPA A; 
#chains in the Genus database with same CATH topology
 1Z5S A;  3HCT B;  4DHZ F;  4P5O G;  5IFR A;  1A3S A;  3TGD A;  5F6U A;  4YC1 A;  3JW0 A;  1X23 A;  4LDT C;  3OBX A;  3RPG A;  4R62 A;  2A4D A;  1WZV A;  2PX9 B;  2Z6P A;  2PWQ A;  2ESQ A;  1U9A A;  3SY2 C;  4LAD A;  3P9H A;  1JBB A;  4QPL B;  1JAT A;  2A7L A;  1JAT B;  2C4P A;  2DAX A;  2Y9P A;  1JAS A;  2NVU C;  2ONU A;  1QCQ A;  3ONG B;  5HPT C;  4DDG A;  2O25 A;  1Z3D A;  4NRG A;  5EGG A;  4NRG B;  4DDI A;  4L83 A;  1S1Q A;  2PE6 A;  5AIE B;  4DHI D;  1ZGU A;  2DAW A;  2AAK A;  4ZNY A;  5D0K A;  3CEG A;  3EVX A;  1WZW A;  1ZUO A;  3F92 A;  5F6X A;  3UIP A;  1KPS A;  2GMI B;  3OBS A;  4Q5E C;  2FUH A;  4Y1L C;  2MT6 A;  1U9B A;  3WE5 A;  4CCG A;  2CLW A;  5D1M A;  2BF8 A;  2CLW B;  1Y6L A;  3K9O A;  2OXQ A;  2YB6 A;  1YH2 A;  2GRP A;  3FN1 B;  3PTF A;  2F0R A;  3UIO A;  3E95 C;  1KPP A;  2QGX A;  3UIN A;  5F6V A;  1PZV A;  5DFL A;  4EJE A;  5F6E A;  3OBU A;  3UGB A;  2HLW A;  2Y4W A;  2Y9M A;  2R0J A;  4A4B C;  5FER B;  4V3K A;  2ESO A;  2GRN A;  3O2U A;  2K07 A;  4BWF A;  4YII U;  5JNE B;  1M4P A;  5FQ2 A;  5F6D A;  2GRR A;  3R42 A;  1FBV C;  5KNL C;  2AWF A;  4ONL A;  4ONL B;  4A49 B;  2GRQ A;  1Z2U A;  2GMI A;  2LXP A;  2OB4 A;  3VON C;  4TKP A;  2H2Y A;  2Q0V A;  1J7D B;  1ZDN A;  2GJD A;  3FSH A;  4DS2 A;  4MDK A;  3JVZ A;  1TTE A;  2EKE A;  1Y8X A;  2ESP A;  4NR3 B;  5F6W A;  4AUQ A;  1FXT A;  2Z5D A;  1YF9 A;  2CYX A;  2EBM A;  2DMF A;  1C4Z D;  2EBK A;  2KLY A;  3A4S A;  4FH1 A;  4II2 C;  4Q5H C;  3EB6 B;  4X57 A;  5D0M A;  1W4U A;  4Y1L A;  3BZH A;  3K9P A;  3OBQ A;  4JUE A;  4DHJ C;  1Q34 A;  2UYZ A;  1UZX A;  1UKX A;  4V3L A;  3OJ4 A;  3L1Y A;  4ONM A;  3R3Q A;  4ONM B;  4S3O A;  3E95 A;  2YBF A;  1I7K A;  4A4C C;  4GPR A;  4W5V A;  2DAY A;  2XWU A;  3SQV C;  2YHO B;  2FO3 A;  1KPQ A;  2UCZ A;  2YZ0 A;  2GRO A;  1J74 A;  2EDI A;  4NRI A;  4NRI B;  5AIT B;  5AIU B;  1YLA A;  5D1K A;  3ZNI C;  4AP4 B;  1J7D A;  3P9G A;  3W31 B;  1YRV A;  2KJH A;  2O25 C;  4WZ3 A;  2F4Z A;  5F6Y A;  4NR3 A;  5D2M A;  1AYZ A;  3L1Z A;  2Z6O A;  2AYV A;  3E46 A;  4M1N A;  3VON B;  2BEP A;  3H8K A;  2F4W A;  2C2V C;  2VRR A;  3A33 A;  2E2C A;  4BVU B;  5AIT D;  5D1L A;  4IP3 B;  2ESK A;  4JQU A;  3RCZ B;  1M4Q A;  3RZ3 A;  2C2V B;  3HCU B;  1FZY A;  4ONN A;  3ZQS A;  4ONN B;  3KPA A; 
#chains in the Genus database with same CATH homology
 1Z5S A;  3HCT B;  4DHZ F;  4P5O G;  5IFR A;  1A3S A;  3TGD A;  5F6U A;  4YC1 A;  3JW0 A;  1X23 A;  4LDT C;  3OBX A;  3RPG A;  4R62 A;  2A4D A;  1WZV A;  2PX9 B;  2Z6P A;  2PWQ A;  2ESQ A;  1U9A A;  3SY2 C;  4LAD A;  3P9H A;  1JBB A;  4QPL B;  1JAT A;  2A7L A;  1JAT B;  2C4P A;  2DAX A;  2Y9P A;  1JAS A;  2NVU C;  2ONU A;  1QCQ A;  3ONG B;  5HPT C;  4DDG A;  2O25 A;  1Z3D A;  4NRG A;  5EGG A;  4NRG B;  4DDI A;  4L83 A;  1S1Q A;  2PE6 A;  5AIE B;  4DHI D;  1ZGU A;  2DAW A;  2AAK A;  4ZNY A;  5D0K A;  3CEG A;  3EVX A;  1WZW A;  1ZUO A;  3F92 A;  5F6X A;  3UIP A;  1KPS A;  2GMI B;  3OBS A;  4Q5E C;  2FUH A;  4Y1L C;  2MT6 A;  1U9B A;  3WE5 A;  4CCG A;  2CLW A;  5D1M A;  2BF8 A;  2CLW B;  1Y6L A;  3K9O A;  2OXQ A;  2YB6 A;  1YH2 A;  2GRP A;  3FN1 B;  3PTF A;  2F0R A;  3UIO A;  3E95 C;  1KPP A;  2QGX A;  3UIN A;  5F6V A;  1PZV A;  5DFL A;  4EJE A;  5F6E A;  3OBU A;  3UGB A;  2HLW A;  2Y4W A;  2Y9M A;  2R0J A;  4A4B C;  5FER B;  4V3K A;  2ESO A;  2GRN A;  3O2U A;  2K07 A;  4BWF A;  4YII U;  5JNE B;  1M4P A;  5FQ2 A;  5F6D A;  2GRR A;  3R42 A;  1FBV C;  5KNL C;  2AWF A;  4ONL A;  4ONL B;  4A49 B;  2GRQ A;  1Z2U A;  2GMI A;  2LXP A;  2OB4 A;  3VON C;  4TKP A;  2H2Y A;  2Q0V A;  1J7D B;  1ZDN A;  2GJD A;  3FSH A;  4DS2 A;  4MDK A;  3JVZ A;  1TTE A;  2EKE A;  1Y8X A;  2ESP A;  4NR3 B;  5F6W A;  4AUQ A;  1FXT A;  2Z5D A;  1YF9 A;  2CYX A;  2EBM A;  2DMF A;  1C4Z D;  2EBK A;  2KLY A;  3A4S A;  4FH1 A;  4II2 C;  4Q5H C;  3EB6 B;  4X57 A;  5D0M A;  1W4U A;  4Y1L A;  3BZH A;  3K9P A;  3OBQ A;  4JUE A;  4DHJ C;  1Q34 A;  2UYZ A;  1UZX A;  1UKX A;  4V3L A;  3OJ4 A;  3L1Y A;  4ONM A;  3R3Q A;  4ONM B;  4S3O A;  3E95 A;  2YBF A;  1I7K A;  4A4C C;  4GPR A;  4W5V A;  2DAY A;  2XWU A;  3SQV C;  2YHO B;  2FO3 A;  1KPQ A;  2UCZ A;  2YZ0 A;  2GRO A;  1J74 A;  2EDI A;  4NRI A;  4NRI B;  5AIT B;  5AIU B;  1YLA A;  5D1K A;  3ZNI C;  4AP4 B;  1J7D A;  3P9G A;  3W31 B;  1YRV A;  2KJH A;  2O25 C;  4WZ3 A;  2F4Z A;  5F6Y A;  4NR3 A;  5D2M A;  1AYZ A;  3L1Z A;  2Z6O A;  2AYV A;  3E46 A;  4M1N A;  3VON B;  2BEP A;  3H8K A;  2F4W A;  2C2V C;  2VRR A;  3A33 A;  2E2C A;  4BVU B;  5AIT D;  5D1L A;  4IP3 B;  2ESK A;  4JQU A;  3RCZ B;  1M4Q A;  3RZ3 A;  2C2V B;  3HCU B;  1FZY A;  4ONN A;  3ZQS A;  4ONN B;  3KPA A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

5HPTC

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations