5IFR | Genus

Total Genus 44

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	44
sequence length	151
structure length	151
Chain Sequence	GPLGSALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Homo sapiens
publication title	A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes. pubmed doi rcsb
molecule keywords	Ubiquitin-conjugating enzyme E2 D3
total genus	44
structure length	151
sequence length	151
ec nomenclature	ec 2.3.2.23: E2 ubiquitin-conjugating enzyme.
pdb deposition date	2016-02-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00179	UQ_con	Ubiquitin-conjugating enzyme

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.110.10	Alpha Beta	Roll	Ubiquitin Conjugating Enzyme	Ubiquitin Conjugating Enzyme	5ifrA00

5D0KA 2EDIA 1C4ZD 3EB6B 3RPGA 1AYZA 2UYZA 2BF8A 2UCZA 2ESKA 5D1LA 1KPPA 3ONGB 5F6YA 3K9OA 4ONNA 2ESPA 4A4BC 2PWQA 3A4SA 3SQVC 5F6VA 3OBUA 5F6UA 4AP4B 4ONMB 2BEPA 1WZWA 2GROA 3E95C 4FH1A 3UIPA 2C4PA 2CLWB 2EBKA 2EBMA 1Y6LA 2F4ZA 1ZGUA 4DS2A 3TGDA 4NRIA 2GMIB 2Y9PA 2Z6OA 3F92A 4YC1A 4DDIA 1A3SA 2YHOB 1JASA 2CYXA 1QCQA 4V3KA 2NVUC 2C2VC 4ONMA 2Z6PA 4LDTC 4ONNB 5AITD 2AYVA 4EJEA 4A49B 4DHJC 1UZXA 2A4DA 1U9AA 1Y8XA 2FO3A 3RZ3A 4BWFA 2GMIA 4DHZF 4DHID 2H2YA 4NR3A 2DAXA 4AUQA 1YRVA 2HLWA 2OB4A 2E2CA 1I7KA 2DMFA 2AWFA 2GRPA 3OBQA 3PTFA 3OJ4A 4NRIB 4P5OG 3BZHA 5F6WA 3O2UA 1YH2A 2MT6A 5KNLC 2ONUA 5F6XA 4ZNYA 2F0RA 3VONC 1M4PA 2PE6A 2DAYA 4TKPA 2OXQA 5D2MA 1Q34A 1YF9A 2EKEA 2C2VB 3OBXA 1FBVC 1KPQA 4YIIU 3E95A 5JNEB 2O25C 4JUEA 1S1QA 4NR3B 5AIUB 1J74A 3E46A 3JW0A 2ESOA 4WZ3A 3H8KA 2Z5DA 4NRGB 4ONLB 5FERB 3P9HA 4Q5EC 5F6EA 4M1NA 3CEGA 3HCTB 2LXPA 2GRNA 3L1ZA 3EVXA 3OBSA 2XWUA 2QGXA 1TTEA 3R42A 5DFLA 4R62A 1ZUOA 1ZDNA 1Z5SA 5FQ2A 2GJDA 3P9GA 4NRGA 4ONLA 3KPAA 2YB6A 3ZQSA 3UGBA 4L83A 2Q0VA 2K07A 3SY2C 4IP3B 1Z3DA 2DAWA 2VRRA 4Y1LC 2ESQA 4Q5HC 3UINA 1WZVA 2KLYA 3RCZB 5D0MA 5F6DA 3JVZA 4A4CC 4JQUA 2YZ0A 4II2C 2O25A 4CCGA 2GRRA 2Y4WA 5AIEB 2R0JA 5EGGA 1FZYA 1X23A 2PX9B 3FSHA 2AAKA 1W4UA 3R3QA 4LADA 3FN1B 2GRQA 2YBFA 4W5VA 4GPRA 2A7LA 1JBBA 1UKXA 1JATB 3WE5A 4V3LA 1FXTA 3L1YA 5HPTC 4X57A 4DDGA 5D1MA 1YLAA 2F4WA 3HCUB 1M4QA 3VONB 1KPSA 4S3OA 3W31B 5AITB 1J7DB 1PZVA 5D1KA 1JATA 4BVUB 3UIOA 2Y9MA 4QPLB 5IFRA 3K9PA 2FUHA 4Y1LA 3ZNIC 4MDKA 1Z2UA 2CLWA 1J7DA 2KJHA 1U9BA 3A33A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5D0K A;  2EDI A;  1C4Z D;  3EB6 B;  3RPG A;  1AYZ A;  2UYZ A;  2BF8 A;  2UCZ A;  2ESK A;  5D1L A;  1KPP A;  3ONG B;  5F6Y A;  3K9O A;  4ONN A;  2ESP A;  4A4B C;  2PWQ A;  3A4S A;  3SQV C;  5F6V A;  3OBU A;  5F6U A;  4AP4 B;  4ONM B;  2BEP A;  1WZW A;  2GRO A;  3E95 C;  4FH1 A;  3UIP A;  2C4P A;  2CLW B;  2EBK A;  2EBM A;  1Y6L A;  2F4Z A;  1ZGU A;  4DS2 A;  3TGD A;  4NRI A;  2GMI B;  2Y9P A;  2Z6O A;  3F92 A;  4YC1 A;  4DDI A;  1A3S A;  2YHO B;  1JAS A;  2CYX A;  1QCQ A;  4V3K A;  2NVU C;  2C2V C;  4ONM A;  2Z6P A;  4LDT C;  4ONN B;  5AIT D;  2AYV A;  4EJE A;  4A49 B;  4DHJ C;  1UZX A;  2A4D A;  1U9A A;  1Y8X A;  2FO3 A;  3RZ3 A;  4BWF A;  2GMI A;  4DHZ F;  4DHI D;  2H2Y A;  4NR3 A;  2DAX A;  4AUQ A;  1YRV A;  2HLW A;  2OB4 A;  2E2C A;  1I7K A;  2DMF A;  2AWF A;  2GRP A;  3OBQ A;  3PTF A;  3OJ4 A;  4NRI B;  4P5O G;  3BZH A;  5F6W A;  3O2U A;  1YH2 A;  2MT6 A;  5KNL C;  2ONU A;  5F6X A;  4ZNY A;  2F0R A;  3VON C;  1M4P A;  2PE6 A;  2DAY A;  4TKP A;  2OXQ A;  5D2M A;  1Q34 A;  1YF9 A;  2EKE A;  2C2V B;  3OBX A;  1FBV C;  1KPQ A;  4YII U;  3E95 A;  5JNE B;  2O25 C;  4JUE A;  1S1Q A;  4NR3 B;  5AIU B;  1J74 A;  3E46 A;  3JW0 A;  2ESO A;  4WZ3 A;  3H8K A;  2Z5D A;  4NRG B;  4ONL B;  5FER B;  3P9H A;  4Q5E C;  5F6E A;  4M1N A;  3CEG A;  3HCT B;  2LXP A;  2GRN A;  3L1Z A;  3EVX A;  3OBS A;  2XWU A;  2QGX A;  1TTE A;  3R42 A;  5DFL A;  4R62 A;  1ZUO A;  1ZDN A;  1Z5S A;  5FQ2 A;  2GJD A;  3P9G A;  4NRG A;  4ONL A;  3KPA A;  2YB6 A;  3ZQS A;  3UGB A;  4L83 A;  2Q0V A;  2K07 A;  3SY2 C;  4IP3 B;  1Z3D A;  2DAW A;  2VRR A;  4Y1L C;  2ESQ A;  4Q5H C;  3UIN A;  1WZV A;  2KLY A;  3RCZ B;  5D0M A;  5F6D A;  3JVZ A;  4A4C C;  4JQU A;  2YZ0 A;  4II2 C;  2O25 A;  4CCG A;  2GRR A;  2Y4W A;  5AIE B;  2R0J A;  5EGG A;  1FZY A;  1X23 A;  2PX9 B;  3FSH A;  2AAK A;  1W4U A;  3R3Q A;  4LAD A;  3FN1 B;  2GRQ A;  2YBF A;  4W5V A;  4GPR A;  2A7L A;  1JBB A;  1UKX A;  1JAT B;  3WE5 A;  4V3L A;  1FXT A;  3L1Y A;  5HPT C;  4X57 A;  4DDG A;  5D1M A;  1YLA A;  2F4W A;  3HCU B;  1M4Q A;  3VON B;  1KPS A;  4S3O A;  3W31 B;  5AIT B;  1J7D B;  1PZV A;  5D1K A;  1JAT A;  4BVU B;  3UIO A;  2Y9M A;  4QPL B;  5IFR A;  3K9P A;  2FUH A;  4Y1L A;  3ZNI C;  4MDK A;  1Z2U A;  2CLW A;  1J7D A;  2KJH A;  1U9B A;  3A33 A; 
#chains in the Genus database with same CATH topology
 5D0K A;  2EDI A;  1C4Z D;  3EB6 B;  3RPG A;  1AYZ A;  2UYZ A;  2BF8 A;  2UCZ A;  2ESK A;  5D1L A;  1KPP A;  3ONG B;  5F6Y A;  3K9O A;  4ONN A;  2ESP A;  4A4B C;  2PWQ A;  3A4S A;  3SQV C;  5F6V A;  3OBU A;  5F6U A;  4AP4 B;  4ONM B;  2BEP A;  1WZW A;  2GRO A;  3E95 C;  4FH1 A;  3UIP A;  2C4P A;  2CLW B;  2EBK A;  2EBM A;  1Y6L A;  2F4Z A;  1ZGU A;  4DS2 A;  3TGD A;  4NRI A;  2GMI B;  2Y9P A;  2Z6O A;  3F92 A;  4YC1 A;  4DDI A;  1A3S A;  2YHO B;  1JAS A;  2CYX A;  1QCQ A;  4V3K A;  2NVU C;  2C2V C;  4ONM A;  2Z6P A;  4LDT C;  4ONN B;  5AIT D;  2AYV A;  4EJE A;  4A49 B;  4DHJ C;  1UZX A;  2A4D A;  1U9A A;  1Y8X A;  2FO3 A;  3RZ3 A;  4BWF A;  2GMI A;  4DHZ F;  4DHI D;  2H2Y A;  4NR3 A;  2DAX A;  4AUQ A;  1YRV A;  2HLW A;  2OB4 A;  2E2C A;  1I7K A;  2DMF A;  2AWF A;  2GRP A;  3OBQ A;  3PTF A;  3OJ4 A;  4NRI B;  4P5O G;  3BZH A;  5F6W A;  3O2U A;  1YH2 A;  2MT6 A;  5KNL C;  2ONU A;  5F6X A;  4ZNY A;  2F0R A;  3VON C;  1M4P A;  2PE6 A;  2DAY A;  4TKP A;  2OXQ A;  5D2M A;  1Q34 A;  1YF9 A;  2EKE A;  2C2V B;  3OBX A;  1FBV C;  1KPQ A;  4YII U;  3E95 A;  5JNE B;  2O25 C;  4JUE A;  1S1Q A;  4NR3 B;  5AIU B;  1J74 A;  3E46 A;  3JW0 A;  2ESO A;  4WZ3 A;  3H8K A;  2Z5D A;  4NRG B;  4ONL B;  5FER B;  3P9H A;  4Q5E C;  5F6E A;  4M1N A;  3CEG A;  3HCT B;  2LXP A;  2GRN A;  3L1Z A;  3EVX A;  3OBS A;  2XWU A;  2QGX A;  1TTE A;  3R42 A;  5DFL A;  4R62 A;  1ZUO A;  1ZDN A;  1Z5S A;  5FQ2 A;  2GJD A;  3P9G A;  4NRG A;  4ONL A;  3KPA A;  2YB6 A;  3ZQS A;  3UGB A;  4L83 A;  2Q0V A;  2K07 A;  3SY2 C;  4IP3 B;  1Z3D A;  2DAW A;  2VRR A;  4Y1L C;  2ESQ A;  4Q5H C;  3UIN A;  1WZV A;  2KLY A;  3RCZ B;  5D0M A;  5F6D A;  3JVZ A;  4A4C C;  4JQU A;  2YZ0 A;  4II2 C;  2O25 A;  4CCG A;  2GRR A;  2Y4W A;  5AIE B;  2R0J A;  5EGG A;  1FZY A;  1X23 A;  2PX9 B;  3FSH A;  2AAK A;  1W4U A;  3R3Q A;  4LAD A;  3FN1 B;  2GRQ A;  2YBF A;  4W5V A;  4GPR A;  2A7L A;  1JBB A;  1UKX A;  1JAT B;  3WE5 A;  4V3L A;  1FXT A;  3L1Y A;  5HPT C;  4X57 A;  4DDG A;  5D1M A;  1YLA A;  2F4W A;  3HCU B;  1M4Q A;  3VON B;  1KPS A;  4S3O A;  3W31 B;  5AIT B;  1J7D B;  1PZV A;  5D1K A;  1JAT A;  4BVU B;  3UIO A;  2Y9M A;  4QPL B;  5IFR A;  3K9P A;  2FUH A;  4Y1L A;  3ZNI C;  4MDK A;  1Z2U A;  2CLW A;  1J7D A;  2KJH A;  1U9B A;  3A33 A; 
#chains in the Genus database with same CATH homology
 5D0K A;  2EDI A;  1C4Z D;  3EB6 B;  3RPG A;  1AYZ A;  2UYZ A;  2BF8 A;  2UCZ A;  2ESK A;  5D1L A;  1KPP A;  3ONG B;  5F6Y A;  3K9O A;  4ONN A;  2ESP A;  4A4B C;  2PWQ A;  3A4S A;  3SQV C;  5F6V A;  3OBU A;  5F6U A;  4AP4 B;  4ONM B;  2BEP A;  1WZW A;  2GRO A;  3E95 C;  4FH1 A;  3UIP A;  2C4P A;  2CLW B;  2EBK A;  2EBM A;  1Y6L A;  2F4Z A;  1ZGU A;  4DS2 A;  3TGD A;  4NRI A;  2GMI B;  2Y9P A;  2Z6O A;  3F92 A;  4YC1 A;  4DDI A;  1A3S A;  2YHO B;  1JAS A;  2CYX A;  1QCQ A;  4V3K A;  2NVU C;  2C2V C;  4ONM A;  2Z6P A;  4LDT C;  4ONN B;  5AIT D;  2AYV A;  4EJE A;  4A49 B;  4DHJ C;  1UZX A;  2A4D A;  1U9A A;  1Y8X A;  2FO3 A;  3RZ3 A;  4BWF A;  2GMI A;  4DHZ F;  4DHI D;  2H2Y A;  4NR3 A;  2DAX A;  4AUQ A;  1YRV A;  2HLW A;  2OB4 A;  2E2C A;  1I7K A;  2DMF A;  2AWF A;  2GRP A;  3OBQ A;  3PTF A;  3OJ4 A;  4NRI B;  4P5O G;  3BZH A;  5F6W A;  3O2U A;  1YH2 A;  2MT6 A;  5KNL C;  2ONU A;  5F6X A;  4ZNY A;  2F0R A;  3VON C;  1M4P A;  2PE6 A;  2DAY A;  4TKP A;  2OXQ A;  5D2M A;  1Q34 A;  1YF9 A;  2EKE A;  2C2V B;  3OBX A;  1FBV C;  1KPQ A;  4YII U;  3E95 A;  5JNE B;  2O25 C;  4JUE A;  1S1Q A;  4NR3 B;  5AIU B;  1J74 A;  3E46 A;  3JW0 A;  2ESO A;  4WZ3 A;  3H8K A;  2Z5D A;  4NRG B;  4ONL B;  5FER B;  3P9H A;  4Q5E C;  5F6E A;  4M1N A;  3CEG A;  3HCT B;  2LXP A;  2GRN A;  3L1Z A;  3EVX A;  3OBS A;  2XWU A;  2QGX A;  1TTE A;  3R42 A;  5DFL A;  4R62 A;  1ZUO A;  1ZDN A;  1Z5S A;  5FQ2 A;  2GJD A;  3P9G A;  4NRG A;  4ONL A;  3KPA A;  2YB6 A;  3ZQS A;  3UGB A;  4L83 A;  2Q0V A;  2K07 A;  3SY2 C;  4IP3 B;  1Z3D A;  2DAW A;  2VRR A;  4Y1L C;  2ESQ A;  4Q5H C;  3UIN A;  1WZV A;  2KLY A;  3RCZ B;  5D0M A;  5F6D A;  3JVZ A;  4A4C C;  4JQU A;  2YZ0 A;  4II2 C;  2O25 A;  4CCG A;  2GRR A;  2Y4W A;  5AIE B;  2R0J A;  5EGG A;  1FZY A;  1X23 A;  2PX9 B;  3FSH A;  2AAK A;  1W4U A;  3R3Q A;  4LAD A;  3FN1 B;  2GRQ A;  2YBF A;  4W5V A;  4GPR A;  2A7L A;  1JBB A;  1UKX A;  1JAT B;  3WE5 A;  4V3L A;  1FXT A;  3L1Y A;  5HPT C;  4X57 A;  4DDG A;  5D1M A;  1YLA A;  2F4W A;  3HCU B;  1M4Q A;  3VON B;  1KPS A;  4S3O A;  3W31 B;  5AIT B;  1J7D B;  1PZV A;  5D1K A;  1JAT A;  4BVU B;  3UIO A;  2Y9M A;  4QPL B;  5IFR A;  3K9P A;  2FUH A;  4Y1L A;  3ZNI C;  4MDK A;  1Z2U A;  2CLW A;  1J7D A;  2KJH A;  1U9B A;  3A33 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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5IFRA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations