2ITLA

The origin binding domain of the sv40 large t antigen bound to the functional pen palindrome dna (23 bp)
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
120
structure length
120
Chain Sequence
DPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Dna binding protein/dna
molecule keywords 24-nt PEN element of the SV40 DNA origin
publication title Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
pubmed doi rcsb
source organism Simian virus 40
total genus 33
structure length 120
sequence length 120
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 2itlA00
3QFQA 2HW0A 4NBPA 1L5IA 2FUFA 3QK2A 1L2MA 4LMDA 2IPRA 2ITJA 4FB3A 5CYNA 4ZO0A 5D9IA 2NL8A 4LIFA 1UUTA 2TBDA 3QN2A 4GDFA 1RZ9A 2ITLA 2NTCA 1Z1DB 5DCXA 4FGNA 2IF9A 5BYGA 4ZQ9A 1M55A 1TBDA
chains in the Genus database with same CATH superfamily
3QFQA 2HW0A 3DKYA 4NBPA 1L5IA 2FUFA 3QK2A 1L2MA 4LMDA 1KSXA 2IPRA 3DKXA 2ITJA 4KW3A 4FB3A 4U87A 5CYNA 4ZO0A 5D9IA 2NL8A 4LIFA 1UUTA 2TBDA 3QN2A 4GDFA 1RZ9A 1KSYA 2ITLA 2NTCA 1Z1DB 5DCXA 1R9WA 4FGNA 2IF9A 5BYGA 4ZQ9A 1F08A 1M55A 1TBDA
chains in the Genus database with same CATH topology
3QFQA 2HW0A 3DKYA 4NBPA 1L5IA 2FUFA 3QK2A 1L2MA 4LMDA 1KSXA 2IPRA 3DKXA 2ITJA 4KW3A 4FB3A 4U87A 5CYNA 4ZO0A 5D9IA 2NL8A 4LIFA 1UUTA 2TBDA 3QN2A 4GDFA 1RZ9A 1KSYA 2ITLA 2NTCA 1Z1DB 5DCXA 1R9WA 4FGNA 2IF9A 5BYGA 4ZQ9A 1F08A 1M55A 1TBDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QFQ A;  2HW0 A;  4NBP A;  1L5I A;  2FUF A;  3QK2 A;  1L2M A;  4LMD A;  2IPR A;  2ITJ A;  4FB3 A;  5CYN A;  4ZO0 A;  5D9I A;  2NL8 A;  4LIF A;  1UUT A;  2TBD A;  3QN2 A;  4GDF A;  1RZ9 A;  2ITL A;  2NTC A;  1Z1D B;  5DCX A;  4FGN A;  2IF9 A;  5BYG A;  4ZQ9 A;  1M55 A;  1TBD A; 
#chains in the Genus database with same CATH topology
 3QFQ A;  2HW0 A;  3DKY A;  4NBP A;  1L5I A;  2FUF A;  3QK2 A;  1L2M A;  4LMD A;  1KSX A;  2IPR A;  3DKX A;  2ITJ A;  4KW3 A;  4FB3 A;  4U87 A;  5CYN A;  4ZO0 A;  5D9I A;  2NL8 A;  4LIF A;  1UUT A;  2TBD A;  3QN2 A;  4GDF A;  1RZ9 A;  1KSY A;  2ITL A;  2NTC A;  1Z1D B;  5DCX A;  1R9W A;  4FGN A;  2IF9 A;  5BYG A;  4ZQ9 A;  1F08 A;  1M55 A;  1TBD A; 
#chains in the Genus database with same CATH homology
 3QFQ A;  2HW0 A;  3DKY A;  4NBP A;  1L5I A;  2FUF A;  3QK2 A;  1L2M A;  4LMD A;  1KSX A;  2IPR A;  3DKX A;  2ITJ A;  4KW3 A;  4FB3 A;  4U87 A;  5CYN A;  4ZO0 A;  5D9I A;  2NL8 A;  4LIF A;  1UUT A;  2TBD A;  3QN2 A;  4GDF A;  1RZ9 A;  1KSY A;  2ITL A;  2NTC A;  1Z1D B;  5DCX A;  1R9W A;  4FGN A;  2IF9 A;  5BYG A;  4ZQ9 A;  1F08 A;  1M55 A;  1TBD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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