3QN2A

Structure-based design of a disulfide-linked oligomeric form of the simian virus 40 (sv40) large t antigen dna binding domain
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
127
structure length
126
Chain Sequence
KVEDPKDFPSELLSFLSHAVCSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLATFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLEHCF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Large T antigen
publication title Structure-based design of a disulfide-linked oligomeric form of the simian virus 40 (SV40) large T antigen DNA-binding domain.
pubmed doi rcsb
source organism Simian virus 40
total genus 30
structure length 126
sequence length 127
ec nomenclature ec 3.6.4.-:
pdb deposition date 2011-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 3qn2A00
2ITJA 4ZQ9A 2NL8A 3QK2A 4NBPA 5CYNA 3QFQA 4FB3A 3QN2A 5BYGA 1UUTA 5DCXA 4ZO0A 1RZ9A 2HW0A 4LMDA 4LIFA 1TBDA 2NTCA 1L5IA 1Z1DB 2IF9A 2ITLA 1M55A 4FGNA 5D9IA 2IPRA 1L2MA 4GDFA 2TBDA 2FUFA
chains in the Genus database with same CATH superfamily
1R9WA 3DKXA 2ITJA 1KSXA 4ZQ9A 2NL8A 1F08A 3QK2A 1KSYA 4NBPA 5CYNA 3QFQA 4FB3A 3DKYA 4KW3A 3QN2A 5BYGA 1UUTA 5DCXA 4ZO0A 1RZ9A 2HW0A 4LMDA 4LIFA 1TBDA 2NTCA 1L5IA 1Z1DB 2IF9A 2ITLA 1M55A 4U87A 4FGNA 5D9IA 2IPRA 1L2MA 4GDFA 2TBDA 2FUFA
chains in the Genus database with same CATH topology
1R9WA 3DKXA 2ITJA 1KSXA 4ZQ9A 2NL8A 1F08A 3QK2A 1KSYA 4NBPA 5CYNA 3QFQA 4FB3A 3DKYA 4KW3A 3QN2A 5BYGA 1UUTA 5DCXA 4ZO0A 1RZ9A 2HW0A 4LMDA 4LIFA 1TBDA 2NTCA 1L5IA 1Z1DB 2IF9A 2ITLA 1M55A 4U87A 4FGNA 5D9IA 2IPRA 1L2MA 4GDFA 2TBDA 2FUFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ITJ A;  4ZQ9 A;  2NL8 A;  3QK2 A;  4NBP A;  5CYN A;  3QFQ A;  4FB3 A;  3QN2 A;  5BYG A;  1UUT A;  5DCX A;  4ZO0 A;  1RZ9 A;  2HW0 A;  4LMD A;  4LIF A;  1TBD A;  2NTC A;  1L5I A;  1Z1D B;  2IF9 A;  2ITL A;  1M55 A;  4FGN A;  5D9I A;  2IPR A;  1L2M A;  4GDF A;  2TBD A;  2FUF A; 
#chains in the Genus database with same CATH topology
 1R9W A;  3DKX A;  2ITJ A;  1KSX A;  4ZQ9 A;  2NL8 A;  1F08 A;  3QK2 A;  1KSY A;  4NBP A;  5CYN A;  3QFQ A;  4FB3 A;  3DKY A;  4KW3 A;  3QN2 A;  5BYG A;  1UUT A;  5DCX A;  4ZO0 A;  1RZ9 A;  2HW0 A;  4LMD A;  4LIF A;  1TBD A;  2NTC A;  1L5I A;  1Z1D B;  2IF9 A;  2ITL A;  1M55 A;  4U87 A;  4FGN A;  5D9I A;  2IPR A;  1L2M A;  4GDF A;  2TBD A;  2FUF A; 
#chains in the Genus database with same CATH homology
 1R9W A;  3DKX A;  2ITJ A;  1KSX A;  4ZQ9 A;  2NL8 A;  1F08 A;  3QK2 A;  1KSY A;  4NBP A;  5CYN A;  3QFQ A;  4FB3 A;  3DKY A;  4KW3 A;  3QN2 A;  5BYG A;  1UUT A;  5DCX A;  4ZO0 A;  1RZ9 A;  2HW0 A;  4LMD A;  4LIF A;  1TBD A;  2NTC A;  1L5I A;  1Z1D B;  2IF9 A;  2ITL A;  1M55 A;  4U87 A;  4FGN A;  5D9I A;  2IPR A;  1L2M A;  4GDF A;  2TBD A;  2FUF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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