2NL8A

The origin binding domain of the sv40 large t antigen bound non specifically to a 17 bp palindrome dna (sites 1 and 3)
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
117
structure length
117
Chain Sequence
EDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLSTFSFLICKGVNKEYLMYSALTRDPFSVIEESLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Dna binding protein/dna
molecule keywords 18-nt PEN element of the SV40 DNA origin
publication title Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
pubmed doi rcsb
source organism Simian virus 40
total genus 29
structure length 117
sequence length 117
ec nomenclature
pdb deposition date 2006-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 2nl8A00
4LIFA 2NL8A 1L2MA 2IF9A 4FB3A 2FUFA 4NBPA 1Z1DB 2ITLA 2IPRA 1RZ9A 4FGNA 4ZQ9A 4GDFA 5BYGA 5CYNA 1M55A 1TBDA 3QFQA 3QN2A 5D9IA 1UUTA 4ZO0A 3QK2A 2NTCA 1L5IA 2HW0A 4LMDA 5DCXA 2ITJA 2TBDA
chains in the Genus database with same CATH superfamily
4LIFA 1KSYA 2NL8A 1KSXA 1L2MA 2IF9A 4FB3A 2FUFA 1F08A 4NBPA 1Z1DB 2ITLA 2IPRA 1RZ9A 4FGNA 3DKYA 4ZQ9A 4GDFA 5BYGA 5CYNA 1M55A 1TBDA 1R9WA 3QFQA 3QN2A 5D9IA 1UUTA 4ZO0A 3QK2A 2NTCA 1L5IA 2HW0A 3DKXA 4KW3A 4LMDA 4U87A 5DCXA 2ITJA 2TBDA
chains in the Genus database with same CATH topology
4LIFA 1KSYA 2NL8A 1KSXA 1L2MA 2IF9A 4FB3A 2FUFA 1F08A 4NBPA 1Z1DB 2ITLA 2IPRA 1RZ9A 4FGNA 3DKYA 4ZQ9A 4GDFA 5BYGA 5CYNA 1M55A 1TBDA 1R9WA 3QFQA 3QN2A 5D9IA 1UUTA 4ZO0A 3QK2A 2NTCA 1L5IA 2HW0A 3DKXA 4KW3A 4LMDA 4U87A 5DCXA 2ITJA 2TBDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LIF A;  2NL8 A;  1L2M A;  2IF9 A;  4FB3 A;  2FUF A;  4NBP A;  1Z1D B;  2ITL A;  2IPR A;  1RZ9 A;  4FGN A;  4ZQ9 A;  4GDF A;  5BYG A;  5CYN A;  1M55 A;  1TBD A;  3QFQ A;  3QN2 A;  5D9I A;  1UUT A;  4ZO0 A;  3QK2 A;  2NTC A;  1L5I A;  2HW0 A;  4LMD A;  5DCX A;  2ITJ A;  2TBD A; 
#chains in the Genus database with same CATH topology
 4LIF A;  1KSY A;  2NL8 A;  1KSX A;  1L2M A;  2IF9 A;  4FB3 A;  2FUF A;  1F08 A;  4NBP A;  1Z1D B;  2ITL A;  2IPR A;  1RZ9 A;  4FGN A;  3DKY A;  4ZQ9 A;  4GDF A;  5BYG A;  5CYN A;  1M55 A;  1TBD A;  1R9W A;  3QFQ A;  3QN2 A;  5D9I A;  1UUT A;  4ZO0 A;  3QK2 A;  2NTC A;  1L5I A;  2HW0 A;  3DKX A;  4KW3 A;  4LMD A;  4U87 A;  5DCX A;  2ITJ A;  2TBD A; 
#chains in the Genus database with same CATH homology
 4LIF A;  1KSY A;  2NL8 A;  1KSX A;  1L2M A;  2IF9 A;  4FB3 A;  2FUF A;  1F08 A;  4NBP A;  1Z1D B;  2ITL A;  2IPR A;  1RZ9 A;  4FGN A;  3DKY A;  4ZQ9 A;  4GDF A;  5BYG A;  5CYN A;  1M55 A;  1TBD A;  1R9W A;  3QFQ A;  3QN2 A;  5D9I A;  1UUT A;  4ZO0 A;  3QK2 A;  2NTC A;  1L5I A;  2HW0 A;  3DKX A;  4KW3 A;  4LMD A;  4U87 A;  5DCX A;  2ITJ A;  2TBD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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