4LIFA

Crystal structure of the jcv large t-antigen origin binding domain
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
127
structure length
127
Chain Sequence
VEDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDFN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase, dna binding protein
molecule keywords Large T antigen
publication title Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
pubmed doi rcsb
source organism Jc polyomavirus
total genus 28
structure length 127
sequence length 127
ec nomenclature ec 3.6.4.-:
pdb deposition date 2013-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 4lifA00
1L5IA 4ZQ9A 2ITJA 2NTCA 1L2MA 2IF9A 3QN2A 5BYGA 5D9IA 4FB3A 1TBDA 4FGNA 2HW0A 4GDFA 3QK2A 2FUFA 1RZ9A 5DCXA 3QFQA 4LMDA 1Z1DB 2ITLA 4LIFA 2IPRA 2NL8A 2TBDA 4NBPA 1UUTA 5CYNA 1M55A 4ZO0A
chains in the Genus database with same CATH superfamily
1L5IA 4ZQ9A 2ITJA 2NTCA 1L2MA 2IF9A 3QN2A 5BYGA 5D9IA 4FB3A 3DKXA 1TBDA 4FGNA 2HW0A 1KSXA 4GDFA 1KSYA 3QK2A 2FUFA 4U87A 4KW3A 3DKYA 1F08A 1RZ9A 5DCXA 1R9WA 3QFQA 4LMDA 1Z1DB 2ITLA 4LIFA 2IPRA 2NL8A 2TBDA 4NBPA 1UUTA 5CYNA 1M55A 4ZO0A
chains in the Genus database with same CATH topology
1L5IA 4ZQ9A 2ITJA 2NTCA 1L2MA 2IF9A 3QN2A 5BYGA 5D9IA 4FB3A 3DKXA 1TBDA 4FGNA 2HW0A 1KSXA 4GDFA 1KSYA 3QK2A 2FUFA 4U87A 4KW3A 3DKYA 1F08A 1RZ9A 5DCXA 1R9WA 3QFQA 4LMDA 1Z1DB 2ITLA 4LIFA 2IPRA 2NL8A 2TBDA 4NBPA 1UUTA 5CYNA 1M55A 4ZO0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1L5I A;  4ZQ9 A;  2ITJ A;  2NTC A;  1L2M A;  2IF9 A;  3QN2 A;  5BYG A;  5D9I A;  4FB3 A;  1TBD A;  4FGN A;  2HW0 A;  4GDF A;  3QK2 A;  2FUF A;  1RZ9 A;  5DCX A;  3QFQ A;  4LMD A;  1Z1D B;  2ITL A;  4LIF A;  2IPR A;  2NL8 A;  2TBD A;  4NBP A;  1UUT A;  5CYN A;  1M55 A;  4ZO0 A; 
#chains in the Genus database with same CATH topology
 1L5I A;  4ZQ9 A;  2ITJ A;  2NTC A;  1L2M A;  2IF9 A;  3QN2 A;  5BYG A;  5D9I A;  4FB3 A;  3DKX A;  1TBD A;  4FGN A;  2HW0 A;  1KSX A;  4GDF A;  1KSY A;  3QK2 A;  2FUF A;  4U87 A;  4KW3 A;  3DKY A;  1F08 A;  1RZ9 A;  5DCX A;  1R9W A;  3QFQ A;  4LMD A;  1Z1D B;  2ITL A;  4LIF A;  2IPR A;  2NL8 A;  2TBD A;  4NBP A;  1UUT A;  5CYN A;  1M55 A;  4ZO0 A; 
#chains in the Genus database with same CATH homology
 1L5I A;  4ZQ9 A;  2ITJ A;  2NTC A;  1L2M A;  2IF9 A;  3QN2 A;  5BYG A;  5D9I A;  4FB3 A;  3DKX A;  1TBD A;  4FGN A;  2HW0 A;  1KSX A;  4GDF A;  1KSY A;  3QK2 A;  2FUF A;  4U87 A;  4KW3 A;  3DKY A;  1F08 A;  1RZ9 A;  5DCX A;  1R9W A;  3QFQ A;  4LMD A;  1Z1D B;  2ITL A;  4LIF A;  2IPR A;  2NL8 A;  2TBD A;  4NBP A;  1UUT A;  5CYN A;  1M55 A;  4ZO0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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