4LMDA

Crystal structure of the jcv large t-antigen origin binding domain
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
128
structure length
128
Chain Sequence
EDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDFNPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Large T antigen
publication title Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
pubmed doi rcsb
source organism Jc polyomavirus
total genus 38
structure length 128
sequence length 128
chains with identical sequence B
ec nomenclature ec 3.6.4.-:
pdb deposition date 2013-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 4lmdA00
2IF9A 4FGNA 5D9IA 1RZ9A 1UUTA 4GDFA 2TBDA 4NBPA 5CYNA 4LIFA 1L2MA 1Z1DB 4LMDA 1TBDA 3QK2A 4ZQ9A 4ZO0A 2NTCA 2NL8A 5DCXA 2IPRA 1L5IA 5BYGA 1M55A 3QN2A 2ITJA 3QFQA 2ITLA 4FB3A 2FUFA 2HW0A
chains in the Genus database with same CATH superfamily
2IF9A 1F08A 4FGNA 1KSYA 5D9IA 1RZ9A 1UUTA 4U87A 2TBDA 4NBPA 5CYNA 1KSXA 4GDFA 4LIFA 1L2MA 1Z1DB 1R9WA 4LMDA 1TBDA 3DKXA 3QK2A 4ZQ9A 4ZO0A 2NTCA 2NL8A 5DCXA 2IPRA 1L5IA 5BYGA 1M55A 3QN2A 2ITJA 3QFQA 4KW3A 2ITLA 4FB3A 2FUFA 2HW0A 3DKYA
chains in the Genus database with same CATH topology
2IF9A 1F08A 4FGNA 1KSYA 5D9IA 1RZ9A 1UUTA 4U87A 2TBDA 4NBPA 5CYNA 1KSXA 4GDFA 4LIFA 1L2MA 1Z1DB 1R9WA 4LMDA 1TBDA 3DKXA 3QK2A 4ZQ9A 4ZO0A 2NTCA 2NL8A 5DCXA 2IPRA 1L5IA 5BYGA 1M55A 3QN2A 2ITJA 3QFQA 4KW3A 2ITLA 4FB3A 2FUFA 2HW0A 3DKYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IF9 A;  4FGN A;  5D9I A;  1RZ9 A;  1UUT A;  4GDF A;  2TBD A;  4NBP A;  5CYN A;  4LIF A;  1L2M A;  1Z1D B;  4LMD A;  1TBD A;  3QK2 A;  4ZQ9 A;  4ZO0 A;  2NTC A;  2NL8 A;  5DCX A;  2IPR A;  1L5I A;  5BYG A;  1M55 A;  3QN2 A;  2ITJ A;  3QFQ A;  2ITL A;  4FB3 A;  2FUF A;  2HW0 A; 
#chains in the Genus database with same CATH topology
 2IF9 A;  1F08 A;  4FGN A;  1KSY A;  5D9I A;  1RZ9 A;  1UUT A;  4U87 A;  2TBD A;  4NBP A;  5CYN A;  1KSX A;  4GDF A;  4LIF A;  1L2M A;  1Z1D B;  1R9W A;  4LMD A;  1TBD A;  3DKX A;  3QK2 A;  4ZQ9 A;  4ZO0 A;  2NTC A;  2NL8 A;  5DCX A;  2IPR A;  1L5I A;  5BYG A;  1M55 A;  3QN2 A;  2ITJ A;  3QFQ A;  4KW3 A;  2ITL A;  4FB3 A;  2FUF A;  2HW0 A;  3DKY A; 
#chains in the Genus database with same CATH homology
 2IF9 A;  1F08 A;  4FGN A;  1KSY A;  5D9I A;  1RZ9 A;  1UUT A;  4U87 A;  2TBD A;  4NBP A;  5CYN A;  1KSX A;  4GDF A;  4LIF A;  1L2M A;  1Z1D B;  1R9W A;  4LMD A;  1TBD A;  3DKX A;  3QK2 A;  4ZQ9 A;  4ZO0 A;  2NTC A;  2NL8 A;  5DCX A;  2IPR A;  1L5I A;  5BYG A;  1M55 A;  3QN2 A;  2ITJ A;  3QFQ A;  4KW3 A;  2ITL A;  4FB3 A;  2FUF A;  2HW0 A;  3DKY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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