5CYNA

Jc virus large t-antigen origin binding domain f258l mutant
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
127
structure length
127
Chain Sequence
VEDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Viral protein, dna binding protein
molecule keywords Large T antigen
publication title Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains.
pubmed doi rcsb
source organism Jc polyomavirus
total genus 32
structure length 127
sequence length 127
ec nomenclature ec 3.6.4.-:
pdb deposition date 2015-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 5cynA00
1TBDA 3QK2A 2IPRA 1Z1DB 2ITLA 1L5IA 4LMDA 2TBDA 2FUFA 2ITJA 5DCXA 2IF9A 3QFQA 1L2MA 2NTCA 2HW0A 5BYGA 4ZO0A 1RZ9A 4FB3A 4ZQ9A 1M55A 2NL8A 5CYNA 4LIFA 4GDFA 5D9IA 1UUTA 4FGNA 3QN2A 4NBPA
chains in the Genus database with same CATH superfamily
1KSXA 1TBDA 3QK2A 2IPRA 4U87A 1Z1DB 2ITLA 1L5IA 1F08A 3DKXA 4LMDA 2TBDA 2FUFA 1R9WA 2ITJA 4KW3A 5DCXA 2IF9A 3QFQA 1L2MA 2NTCA 2HW0A 5BYGA 3DKYA 4ZO0A 1RZ9A 1KSYA 4FB3A 4ZQ9A 1M55A 2NL8A 5CYNA 4LIFA 4GDFA 5D9IA 1UUTA 4FGNA 3QN2A 4NBPA
chains in the Genus database with same CATH topology
1KSXA 1TBDA 3QK2A 2IPRA 4U87A 1Z1DB 2ITLA 1L5IA 1F08A 3DKXA 4LMDA 2TBDA 2FUFA 1R9WA 2ITJA 4KW3A 5DCXA 2IF9A 3QFQA 1L2MA 2NTCA 2HW0A 5BYGA 3DKYA 4ZO0A 1RZ9A 1KSYA 4FB3A 4ZQ9A 1M55A 2NL8A 5CYNA 4LIFA 4GDFA 5D9IA 1UUTA 4FGNA 3QN2A 4NBPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TBD A;  3QK2 A;  2IPR A;  1Z1D B;  2ITL A;  1L5I A;  4LMD A;  2TBD A;  2FUF A;  2ITJ A;  5DCX A;  2IF9 A;  3QFQ A;  1L2M A;  2NTC A;  2HW0 A;  5BYG A;  4ZO0 A;  1RZ9 A;  4FB3 A;  4ZQ9 A;  1M55 A;  2NL8 A;  5CYN A;  4LIF A;  4GDF A;  5D9I A;  1UUT A;  4FGN A;  3QN2 A;  4NBP A; 
#chains in the Genus database with same CATH topology
 1KSX A;  1TBD A;  3QK2 A;  2IPR A;  4U87 A;  1Z1D B;  2ITL A;  1L5I A;  1F08 A;  3DKX A;  4LMD A;  2TBD A;  2FUF A;  1R9W A;  2ITJ A;  4KW3 A;  5DCX A;  2IF9 A;  3QFQ A;  1L2M A;  2NTC A;  2HW0 A;  5BYG A;  3DKY A;  4ZO0 A;  1RZ9 A;  1KSY A;  4FB3 A;  4ZQ9 A;  1M55 A;  2NL8 A;  5CYN A;  4LIF A;  4GDF A;  5D9I A;  1UUT A;  4FGN A;  3QN2 A;  4NBP A; 
#chains in the Genus database with same CATH homology
 1KSX A;  1TBD A;  3QK2 A;  2IPR A;  4U87 A;  1Z1D B;  2ITL A;  1L5I A;  1F08 A;  3DKX A;  4LMD A;  2TBD A;  2FUF A;  1R9W A;  2ITJ A;  4KW3 A;  5DCX A;  2IF9 A;  3QFQ A;  1L2M A;  2NTC A;  2HW0 A;  5BYG A;  3DKY A;  4ZO0 A;  1RZ9 A;  1KSY A;  4FB3 A;  4ZQ9 A;  1M55 A;  2NL8 A;  5CYN A;  4LIF A;  4GDF A;  5D9I A;  1UUT A;  4FGN A;  3QN2 A;  4NBP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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