3S4MA

Crystal structure of wild-type human frataxin
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
121
structure length
121
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
pubmed doi rcsb
molecule tags Unknown function
source organism Homo sapiens
molecule keywords Frataxin, mitochondrial
total genus 35
structure length 121
sequence length 121
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3s4mA00
3OERA 4LK8A 2EFFA 3T3XA 1EKGA 1EW4A 1LY7A 4JPDA 2GA5A 3T3TA 3S5EA 2FQLA 3S4MA 4HS5A 4LP1A 3OEQA 3T3JA 3S5FA 3S5DA 2P1XA 3T3KA 4EC2A 3T3LA 1SOYA
chains in the Genus database with same CATH superfamily
3I9V7 3OERA 4LK8A 1D2MA 2EFFA 3T3XA 1EKGA 3GD0A 3SSDA 3IAS7 1EW4A 1WHZA 3SSCA 3IAM7 1LY7A 4JPDA 2GA5A 3T3TA 3S5EA 2FQLA 4HS5A 3S4MA 4HEA7 4LP1A 2FUG7 3IMOA 3OEQA 3SSEA 3T3JA 3S5FA 1V5RA 2P1XA 3S5DA 4P78C 4C26A 3GD9A 3T3KA 4EC2A 3A5PA 3T3LA 1SOYA
chains in the Genus database with same CATH topology
3OERA 4LK8A 2EFFA 3T3XA 1EKGA 1EW4A 1LY7A 4JPDA 2GA5A 3T3TA 3S5EA 2FQLA 3S4MA 4HS5A 4LP1A 3OEQA 3T3JA 3S5FA 3S5DA 2P1XA 3T3KA 4EC2A 3T3LA 1SOYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OER A;  4LK8 A;  2EFF A;  3T3X A;  1EKG A;  1EW4 A;  1LY7 A;  4JPD A;  2GA5 A;  3T3T A;  3S5E A;  2FQL A;  3S4M A;  4HS5 A;  4LP1 A;  3OEQ A;  3T3J A;  3S5F A;  3S5D A;  2P1X A;  3T3K A;  4EC2 A;  3T3L A;  1SOY A; 
#chains in the Genus database with same CATH topology
 3I9V 7;  3OER A;  4LK8 A;  1D2M A;  2EFF A;  3T3X A;  1EKG A;  3GD0 A;  3SSD A;  3IAS 7;  1EW4 A;  1WHZ A;  3SSC A;  3IAM 7;  1LY7 A;  4JPD A;  2GA5 A;  3T3T A;  3S5E A;  2FQL A;  4HS5 A;  3S4M A;  4HEA 7;  4LP1 A;  2FUG 7;  3IMO A;  3OEQ A;  3SSE A;  3T3J A;  3S5F A;  1V5R A;  2P1X A;  3S5D A;  4P78 C;  4C26 A;  3GD9 A;  3T3K A;  4EC2 A;  3A5P A;  3T3L A;  1SOY A; 
#chains in the Genus database with same CATH homology
 3OER A;  4LK8 A;  2EFF A;  3T3X A;  1EKG A;  1EW4 A;  1LY7 A;  4JPD A;  2GA5 A;  3T3T A;  3S5E A;  2FQL A;  3S4M A;  4HS5 A;  4LP1 A;  3OEQ A;  3T3J A;  3S5F A;  3S5D A;  2P1X A;  3T3K A;  4EC2 A;  3T3L A;  1SOY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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