3T3XA

1.57 a structure of friedreich's ataxia frataxin variant r165c
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
122
structure length
122
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKCYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Frataxin, mitochondrial
publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
source organism Homo sapiens
total genus 35
structure length 122
sequence length 122
chains with identical sequence B
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3xA00
3T3JA 4JPDA 1SOYA 3T3KA 1EKGA 3T3XA 2EFFA 4EC2A 4HS5A 4LP1A 2GA5A 3S5FA 3S5EA 2P1XA 3S4MA 2FQLA 1LY7A 4LK8A 1EW4A 3OEQA 3T3LA 3T3TA 3OERA 3S5DA
chains in the Genus database with same CATH superfamily
3T3JA 1D2MA 3SSEA 3A5PA 4JPDA 1SOYA 3SSDA 1V5RA 4HEA7 3T3KA 1EKGA 3T3XA 2EFFA 3IAS7 4EC2A 4HS5A 4LP1A 2GA5A 3S5FA 3S5EA 3GD9A 2P1XA 3IMOA 3S4MA 2FQLA 1LY7A 4LK8A 3I9V7 3SSCA 1EW4A 3OEQA 3T3LA 3IAM7 3GD0A 1WHZA 4P78C 3T3TA 2FUG7 4C26A 3OERA 3S5DA
chains in the Genus database with same CATH topology
3T3JA 4JPDA 1SOYA 3T3KA 1EKGA 3T3XA 2EFFA 4EC2A 4HS5A 4LP1A 2GA5A 3S5FA 3S5EA 2P1XA 3S4MA 2FQLA 1LY7A 4LK8A 1EW4A 3OEQA 3T3LA 3T3TA 3OERA 3S5DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T3J A;  4JPD A;  1SOY A;  3T3K A;  1EKG A;  3T3X A;  2EFF A;  4EC2 A;  4HS5 A;  4LP1 A;  2GA5 A;  3S5F A;  3S5E A;  2P1X A;  3S4M A;  2FQL A;  1LY7 A;  4LK8 A;  1EW4 A;  3OEQ A;  3T3L A;  3T3T A;  3OER A;  3S5D A; 
#chains in the Genus database with same CATH topology
 3T3J A;  1D2M A;  3SSE A;  3A5P A;  4JPD A;  1SOY A;  3SSD A;  1V5R A;  4HEA 7;  3T3K A;  1EKG A;  3T3X A;  2EFF A;  3IAS 7;  4EC2 A;  4HS5 A;  4LP1 A;  2GA5 A;  3S5F A;  3S5E A;  3GD9 A;  2P1X A;  3IMO A;  3S4M A;  2FQL A;  1LY7 A;  4LK8 A;  3I9V 7;  3SSC A;  1EW4 A;  3OEQ A;  3T3L A;  3IAM 7;  3GD0 A;  1WHZ A;  4P78 C;  3T3T A;  2FUG 7;  4C26 A;  3OER A;  3S5D A; 
#chains in the Genus database with same CATH homology
 3T3J A;  4JPD A;  1SOY A;  3T3K A;  1EKG A;  3T3X A;  2EFF A;  4EC2 A;  4HS5 A;  4LP1 A;  2GA5 A;  3S5F A;  3S5E A;  2P1X A;  3S4M A;  2FQL A;  1LY7 A;  4LK8 A;  1EW4 A;  3OEQ A;  3T3L A;  3T3T A;  3OER A;  3S5D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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