4EC2A

Crystal structure of trimeric frataxin from the yeast saccharomyces cerevisiae, complexed with ferrous
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
112
structure length
112
Chain Sequence
VPQEVLNLPLEKAHEEADDYLDHLLDSLEELSEAHPDCIPDVELSHGVMTLEIPAFGTYVINKQPPNKQIWLASPLSGPNRFDLLNGEWVSLRNGTKLTDILTEEVEKAISK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords Frataxin homolog, mitochondrial
publication title The molecular basis of iron-induced oligomerization of frataxin and the role of the ferroxidation reaction in oligomerization.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
total genus 20
structure length 112
sequence length 112
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2012-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 4ec2A01
3T3TA 2EFFA 3OEQA 4JPDA 4HS5A 1LY7A 3S5DA 3T3LA 3OERA 3T3JA 4LK8A 1EKGA 4EC2A 3T3KA 4LP1A 1EW4A 3S4MA 2P1XA 1SOYA 2FQLA 2GA5A 3S5FA 3S5EA 3T3XA
chains in the Genus database with same CATH superfamily
3T3TA 3IMOA 2EFFA 3OEQA 4C26A 4JPDA 3GD9A 4HS5A 1LY7A 4P78C 3S5DA 1WHZA 3T3LA 3OERA 3T3JA 4LK8A 3SSCA 1EKGA 2FUG7 1D2MA 4EC2A 3SSEA 3I9V7 3T3KA 4HEA7 4LP1A 1EW4A 3A5PA 3S4MA 3IAS7 2P1XA 3GD0A 3IAM7 1SOYA 2FQLA 1V5RA 2GA5A 3S5FA 3S5EA 3SSDA 3T3XA
chains in the Genus database with same CATH topology
3T3TA 2EFFA 3OEQA 4JPDA 4HS5A 1LY7A 3S5DA 3T3LA 3OERA 3T3JA 4LK8A 1EKGA 4EC2A 3T3KA 4LP1A 1EW4A 3S4MA 2P1XA 1SOYA 2FQLA 2GA5A 3S5FA 3S5EA 3T3XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T3T A;  2EFF A;  3OEQ A;  4JPD A;  4HS5 A;  1LY7 A;  3S5D A;  3T3L A;  3OER A;  3T3J A;  4LK8 A;  1EKG A;  4EC2 A;  3T3K A;  4LP1 A;  1EW4 A;  3S4M A;  2P1X A;  1SOY A;  2FQL A;  2GA5 A;  3S5F A;  3S5E A;  3T3X A; 
#chains in the Genus database with same CATH topology
 3T3T A;  3IMO A;  2EFF A;  3OEQ A;  4C26 A;  4JPD A;  3GD9 A;  4HS5 A;  1LY7 A;  4P78 C;  3S5D A;  1WHZ A;  3T3L A;  3OER A;  3T3J A;  4LK8 A;  3SSC A;  1EKG A;  2FUG 7;  1D2M A;  4EC2 A;  3SSE A;  3I9V 7;  3T3K A;  4HEA 7;  4LP1 A;  1EW4 A;  3A5P A;  3S4M A;  3IAS 7;  2P1X A;  3GD0 A;  3IAM 7;  1SOY A;  2FQL A;  1V5R A;  2GA5 A;  3S5F A;  3S5E A;  3SSD A;  3T3X A; 
#chains in the Genus database with same CATH homology
 3T3T A;  2EFF A;  3OEQ A;  4JPD A;  4HS5 A;  1LY7 A;  3S5D A;  3T3L A;  3OER A;  3T3J A;  4LK8 A;  1EKG A;  4EC2 A;  3T3K A;  4LP1 A;  1EW4 A;  3S4M A;  2P1X A;  1SOY A;  2FQL A;  2GA5 A;  3S5F A;  3S5E A;  3T3X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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