|
96
|
388
|
4friA |
Crystal structure of bace1 in complex with biarylspiro aminooxazoline 6 |
|
99
|
387
|
4fslA |
Crystal structure of beta-site app-cleaving enzyme 1 (bace-db-mut) complex with n-(n-(4- acetamido-3-chloro-5-methylbenzyl)carbamimidoyl)-3-(4- methoxyphenyl)-5-methyl-4-isothiazolecarboxamide |
|
99
|
387
|
4fseA |
Crystal structure of beta-site app-cleaving enzyme 1 (bace-wt) complex with n-(n-(4-amino-3,5- dichlorobenzyl)carbamimidoyl)-3-(4-methoxyphenyl)-5- methyl-4-isothiazolecarboxamide |
|
103
|
387
|
4frjA |
Crystal structure of bace1 in complex with aminooxazoline xanthene 9l |
|
106
|
389
|
4frsA |
Structure of bace in complex with (s)-4-(3-chloro-5-(5-(prop-1-yn-1-yl)pyridin-3-yl)thiophen-2-yl)-1,4-dimethyl-6-oxotetrahydropyrimidin-2(1h)-iminium |
|
105
|
390
|
4fs4A |
Structure of bace bound to (s)-4-(3'-methoxy-[1,1'-biphenyl]-3-yl)-1,4-dimethyl-6-oxotetrahydropyrimidin-2(1h)-iminium |
|
98
|
387
|
4frkA |
Crystal structure of bace1 in complex with aminooxazoline xanthene 11a |
|
16
|
99
|
3r0wA |
Crystal structures of multidrug-resistant hiv-1 protease in complex with mechanism-based aspartyl protease inhibitors. |
|
18
|
99
|
4flgA |
Hiv-1 protease mutant i47v complexed with reaction intermediate |
|
102
|
400
|
4fm8A |
Crystal structure of bace with compound 12a |
|
97
|
389
|
4fcoA |
Crystal structure of bace1 with its inhibitor |
|
103
|
400
|
4fm7A |
Crystal structure of bace with compound 14g |
|
20
|
99
|
4fe6A |
Crystal structure of hiv-1 protease in complex with an enamino-oxindole inhibitor |
|
28
|
113
|
4fivA |
Fiv protease complexed with an inhibitor lp-130 |
|
93
|
392
|
3r1gB |
Structure basis of allosteric inhibition of bace1 by an exosite-binding antibody |
|
97
|
386
|
3r2fA |
Crystal structure of beta-site app-cleaving enzyme 1 (bace-wt) complex with bms-693391 aka (2s)-2-((3r)-3-acetamido-3-isobutyl-2-oxo-1-pyrrolidinyl)-n-((1s,2r)-1-(3,5-difluorobenzyl)-2-hydroxy-2-((2r,4r)-4-propoxy-2-pyrrolidinyl)ethyl)-4-phenylbutanamide |
|
18
|
99
|
4fl8A |
Hiv-1 protease complexed with gem-diol-amine tetrahedral intermediate |
|
16
|
99
|
3r0yA |
Crystal structures of multidrug-resistant hiv-1 protease in complex with mechanism-based aspartyl protease inhibitors |
|
98
|
389
|
4fgxA |
Crystal structure of bace1 with novel inhibitor |
|
19
|
99
|
3r4bA |
Crystal structure of wild-type hiv-1 protease in complex with tmc310911 |
|
19
|
99
|
4fm6A |
Hiv-1 protease mutant v32i complexed with reaction intermediate |
|
17
|
99
|
3qroA |
Hiv-1 protease (mutant q7k l33i l63i) in complex with a three-armed pyrrolidine-based inhibitor |
|
19
|
99
|
3qp0A |
Hiv-1 protease (mutant q7k l33i l63i) in complex with a novel inhibitor |
|
18
|
99
|
3qrmA |
Hiv-1 protease (mutant q7k l33i l63i) in complex with a three-armed pyrrolidine-based inhibitor |
|
19
|
99
|
3qihA |
Hiv-1 protease (mutant q7k l33i l63i) in complex with a novel inhibitor |
|
77
|
327
|
3qs1A |
Crystal structure of kni-10006 complex of plasmepsin i (pmi) from plasmodium falciparum |
|
16
|
99
|
3qpjA |
Hiv-1 protease (mutant q7k l33i l63i) in complex with a three-armed pyrrolidine-based inhibitor |
|
81
|
327
|
3qviA |
Crystal structure of kni-10395 bound histo-aspartic protease (hap) from plasmodium falciparum |
|
97
|
389
|
3qi1A |
Design and synthesis of hydroxyethylamine (hea) bace-1 inhibitors: prime side chromane-containing inhibitors |
|
18
|
99
|
3qn8A |
Hiv-1 protease (mutant q7k l33i l63i) in complex with a novel inhibitor |
|
75
|
328
|
3qrvA |
Crystal structure of plasmepsin i (pmi) from plasmodium falciparum |
|
80
|
375
|
3qvcA |
Crystal structure of histo-aspartic protease (hap) zymogen from plasmodium falciparum |
|
18
|
99
|
3qrsA |
Hiv-1 protease (mutant q7k l33i l63i) in complex with a three-armed pyrrolidine-based inhibitor |
|
18
|
99
|
3qaaA |
Hiv-1 wild type protease with a substituted bis-tetrahydrofuran inhibitor, grl-044-10a |
|
84
|
337
|
3q3tA |
Alkyl amine renin inhibitors: filling s1 from s3 |
|
16
|
99
|
3qbfA |
Hiv-1 protease (mutant q7k l33i l63i) in complex with a three-armed pyrrolidine-based inhibitor |
|
92
|
342
|
3q70A |
Secreted aspartic protease in complex with ritonavir |
|
86
|
330
|
3pwwA |
Endothiapepsin in complex with saquinavir |
|
99
|
388
|
3qbhA |
Structure based design, synthesis and sar of cyclic hydroxyethylamine (hea) bace-1 inhibitors |
|
84
|
337
|
3q4bA |
Clinically useful alkyl amine renin inhibitors |
|
95
|
340
|
3pvkA |
Secreted aspartic protease 2 in complex with benzamidine |
|
80
|
337
|
3q5hA |
Clinically useful alkyl amine renin inhibitors |
|
19
|
99
|
3pwmA |
Hiv-1 protease mutant l76v with darunavir |
|
77
|
330
|
3q6yA |
Endothiapepsin in complex with a pyrrolidine based inhibitor |
|
17
|
99
|
3pwrA |
Hiv-1 protease mutant l76v complexed with saquinavir |
|
84
|
330
|
3psyA |
Endothiapepsin in complex with an inhibitor based on the gewald reaction |
|
83
|
330
|
3pgiA |
Endothiapepsin in complex with a fragment |
|
86
|
330
|
3pmyA |
Endothiapepsin in complex with a fragment |
|
86
|
330
|
3pi0A |
Endothiapepsin in complex with a fragment |
|
84
|
330
|
3prsA |
Endothiapepsin in complex with ritonavir |
