1KB4A

Crystal structure of vdr dna-binding domain bound to a canonical direct repeat with three base pair spacer (dr3) response element
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
93
structure length
93
Chain Sequence
RICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of VDR-DNA interactions on direct repeat response elements.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords 5'-D(*CP*AP*CP*AP*GP*GP*TP*CP*AP*CP*GP*AP*AP*GP*GP*TP*CP*A)-
total genus 24
structure length 93
sequence length 93
chains with identical sequence B
ec nomenclature
pdb deposition date 2001-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00105 zf-C4 Zinc finger, C4 type (two domains)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 1kb4A00
1HCPA 1HRAA 2VUTI 3G8XA 1R0OB 5GATA 3G9JA 3DZUA 4CN3A 1RXRA 3G6TA 2C7AA 1A6YA 3G6UA 1LO1A 1R0OA 1R4OA 5KRBB 4CN7A 5E6BA 2VUSI 1CITA 3G6RA 4HC7A 4HN5A 4OLNA 4GATA 2NLLB 3G9OA 3G6QA 3G6PA 1DSZA 5EMQA 4TMAI 3G8UA 1R4IA 4HCAA 2NLLA 4TNTA 3DFXA 5CC0A 2A66A 1GATA 7GATA 4NQAB 1R0NB 5L0MA 1BY4A 3M9EA 3DFVC 4OORA 2ENVA 1LV3A 2HANB 1YNWB 3GATA 5E6CA 2GDAA 6GATA 3FYLA 3G9MA 2M9WA 1GLUA 2KAEA 5EMCA 3CBBA 4OV7A 3VEKC 3G97A 5E6AA 1LATA 2VUUI 1GAUA 5E6DA 5CBYA 3G9IA 1HCQA 5CC1A 1R0NA 5E69A 1RGDA 5CBXA 3DZYD 5EMPA 3VD6C 1GA5A 2FF0A 2HANA 3G99A 1YNWA 4CN5A 4HN6A 4HC9A 1KB2A 1GDCA 1KB6A 4CN2C 1GNFA 3E00D 3G9PA 3DZYA 1HLZA 4IQRA 1R4RA 4AA6A 4ONDA 1KB4A 5CBZA 1DSZB 2GATA 2EBLA 3DZUD 3E00A 4CN3D
chains in the Genus database with same CATH superfamily
1HCPA 2DS8A 1HRAA 2VUTI 3G8XA 1R0OB 5GATA 3G9JA 3DZUA 4CN3A 1RXRA 3G6TA 2C7AA 1A6YA 3G6UA 1LO1A 1R0OA 1R4OA 5KRBB 4CN7A 5E6BA 2VUSI 1CITA 3G6RA 4HC7A 4HN5A 4OLNA 4GATA 2NLLB 3G9OA 3G6QA 3G6PA 1DSZA 5EMQA 4TMAI 3G8UA 1R4IA 4HCAA 2NLLA 4TNTA 3DFXA 5CC0A 2A66A 1GATA 7GATA 4NQAB 1R0NB 5L0MA 1BY4A 2DS5A 3M9EA 3DFVC 2ENVA 4OORA 1LV3A 2HANB 1YNWB 3GATA 5E6CA 2GDAA 6GATA 3FYLA 3G9MA 2M9WA 1GLUA 2KAEA 5EMCA 3CBBA 4OV7A 3VEKC 3G97A 5E6AA 2DS6A 1LATA 2VUUI 1GAUA 5E6DA 5CBYA 3G9IA 1HCQA 5CC1A 1R0NA 5E69A 1RGDA 5CBXA 3DZYD 5EMPA 3VD6C 1GA5A 2FF0A 2HANA 3G99A 1YNWA 4CN5A 4HN6A 4HC9A 1KB2A 1GDCA 1KB6A 4CN2C 1GNFA 3E00D 3G9PA 3DZYA 1HLZA 4IQRA 1R4RA 4AA6A 4ONDA 3G27A 1KB4A 5CBZA 1DSZB 2GATA 2EBLA 3DZUD 3E00A 4CN3D
chains in the Genus database with same CATH topology
1HCPA 1HRAA 2VUTI 3G8XA 1R0OB 5GATA 3G9JA 3DZUA 4CN3A 1RXRA 3G6TA 2C7AA 1A6YA 3G6UA 1LO1A 1R0OA 1R4OA 5KRBB 4CN7A 5E6BA 2VUSI 1CITA 3G6RA 4HC7A 4HN5A 4OLNA 4GATA 2NLLB 3G9OA 3G6QA 3G6PA 1DSZA 5EMQA 4TMAI 3G8UA 1R4IA 4HCAA 2NLLA 4TNTA 3DFXA 5CC0A 2A66A 1GATA 7GATA 4NQAB 1R0NB 5L0MA 1BY4A 3M9EA 3DFVC 4OORA 2ENVA 1LV3A 2HANB 1YNWB 3GATA 5E6CA 2GDAA 6GATA 3FYLA 3G9MA 2M9WA 1GLUA 2KAEA 5EMCA 3CBBA 4OV7A 3VEKC 3G97A 5E6AA 1LATA 2VUUI 1GAUA 5E6DA 5CBYA 3G9IA 1HCQA 5CC1A 1R0NA 5E69A 1RGDA 5CBXA 3DZYD 5EMPA 3VD6C 1GA5A 2FF0A 2HANA 3G99A 1YNWA 4CN5A 4HN6A 4HC9A 1KB2A 1GDCA 1KB6A 4CN2C 1GNFA 3E00D 3G9PA 3DZYA 1HLZA 4IQRA 1R4RA 4AA6A 4ONDA 1KB4A 5CBZA 1DSZB 2GATA 2EBLA 3DZUD 3E00A 4CN3D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HCP A;  1HRA A;  2VUT I;  3G8X A;  1R0O B;  5GAT A;  3G9J A;  3DZU A;  4CN3 A;  1RXR A;  3G6T A;  2C7A A;  1A6Y A;  3G6U A;  1LO1 A;  1R0O A;  1R4O A;  5KRB B;  4CN7 A;  5E6B A;  2VUS I;  1CIT A;  3G6R A;  4HC7 A;  4HN5 A;  4OLN A;  4GAT A;  2NLL B;  3G9O A;  3G6Q A;  3G6P A;  1DSZ A;  5EMQ A;  4TMA I;  3G8U A;  1R4I A;  4HCA A;  2NLL A;  4TNT A;  3DFX A;  5CC0 A;  2A66 A;  1GAT A;  7GAT A;  4NQA B;  1R0N B;  5L0M A;  1BY4 A;  3M9E A;  3DFV C;  4OOR A;  2ENV A;  1LV3 A;  2HAN B;  1YNW B;  3GAT A;  5E6C A;  2GDA A;  6GAT A;  3FYL A;  3G9M A;  2M9W A;  1GLU A;  2KAE A;  5EMC A;  3CBB A;  4OV7 A;  3VEK C;  3G97 A;  5E6A A;  1LAT A;  2VUU I;  1GAU A;  5E6D A;  5CBY A;  3G9I A;  1HCQ A;  5CC1 A;  1R0N A;  5E69 A;  1RGD A;  5CBX A;  3DZY D;  5EMP A;  3VD6 C;  1GA5 A;  2FF0 A;  2HAN A;  3G99 A;  1YNW A;  4CN5 A;  4HN6 A;  4HC9 A;  1KB2 A;  1GDC A;  1KB6 A;  4CN2 C;  1GNF A;  3E00 D;  3G9P A;  3DZY A;  1HLZ A;  4IQR A;  1R4R A;  4AA6 A;  4OND A;  1KB4 A;  5CBZ A;  1DSZ B;  2GAT A;  2EBL A;  3DZU D;  3E00 A;  4CN3 D; 
#chains in the Genus database with same CATH topology
 1HCP A;  2DS8 A;  1HRA A;  2VUT I;  3G8X A;  1R0O B;  5GAT A;  3G9J A;  3DZU A;  4CN3 A;  1RXR A;  3G6T A;  2C7A A;  1A6Y A;  3G6U A;  1LO1 A;  1R0O A;  1R4O A;  5KRB B;  4CN7 A;  5E6B A;  2VUS I;  1CIT A;  3G6R A;  4HC7 A;  4HN5 A;  4OLN A;  4GAT A;  2NLL B;  3G9O A;  3G6Q A;  3G6P A;  1DSZ A;  5EMQ A;  4TMA I;  3G8U A;  1R4I A;  4HCA A;  2NLL A;  4TNT A;  3DFX A;  5CC0 A;  2A66 A;  1GAT A;  7GAT A;  4NQA B;  1R0N B;  5L0M A;  1BY4 A;  2DS5 A;  3M9E A;  3DFV C;  2ENV A;  4OOR A;  1LV3 A;  2HAN B;  1YNW B;  3GAT A;  5E6C A;  2GDA A;  6GAT A;  3FYL A;  3G9M A;  2M9W A;  1GLU A;  2KAE A;  5EMC A;  3CBB A;  4OV7 A;  3VEK C;  3G97 A;  5E6A A;  2DS6 A;  1LAT A;  2VUU I;  1GAU A;  5E6D A;  5CBY A;  3G9I A;  1HCQ A;  5CC1 A;  1R0N A;  5E69 A;  1RGD A;  5CBX A;  3DZY D;  5EMP A;  3VD6 C;  1GA5 A;  2FF0 A;  2HAN A;  3G99 A;  1YNW A;  4CN5 A;  4HN6 A;  4HC9 A;  1KB2 A;  1GDC A;  1KB6 A;  4CN2 C;  1GNF A;  3E00 D;  3G9P A;  3DZY A;  1HLZ A;  4IQR A;  1R4R A;  4AA6 A;  4OND A;  3G27 A;  1KB4 A;  5CBZ A;  1DSZ B;  2GAT A;  2EBL A;  3DZU D;  3E00 A;  4CN3 D; 
#chains in the Genus database with same CATH homology
 1HCP A;  1HRA A;  2VUT I;  3G8X A;  1R0O B;  5GAT A;  3G9J A;  3DZU A;  4CN3 A;  1RXR A;  3G6T A;  2C7A A;  1A6Y A;  3G6U A;  1LO1 A;  1R0O A;  1R4O A;  5KRB B;  4CN7 A;  5E6B A;  2VUS I;  1CIT A;  3G6R A;  4HC7 A;  4HN5 A;  4OLN A;  4GAT A;  2NLL B;  3G9O A;  3G6Q A;  3G6P A;  1DSZ A;  5EMQ A;  4TMA I;  3G8U A;  1R4I A;  4HCA A;  2NLL A;  4TNT A;  3DFX A;  5CC0 A;  2A66 A;  1GAT A;  7GAT A;  4NQA B;  1R0N B;  5L0M A;  1BY4 A;  3M9E A;  3DFV C;  4OOR A;  2ENV A;  1LV3 A;  2HAN B;  1YNW B;  3GAT A;  5E6C A;  2GDA A;  6GAT A;  3FYL A;  3G9M A;  2M9W A;  1GLU A;  2KAE A;  5EMC A;  3CBB A;  4OV7 A;  3VEK C;  3G97 A;  5E6A A;  1LAT A;  2VUU I;  1GAU A;  5E6D A;  5CBY A;  3G9I A;  1HCQ A;  5CC1 A;  1R0N A;  5E69 A;  1RGD A;  5CBX A;  3DZY D;  5EMP A;  3VD6 C;  1GA5 A;  2FF0 A;  2HAN A;  3G99 A;  1YNW A;  4CN5 A;  4HN6 A;  4HC9 A;  1KB2 A;  1GDC A;  1KB6 A;  4CN2 C;  1GNF A;  3E00 D;  3G9P A;  3DZY A;  1HLZ A;  4IQR A;  1R4R A;  4AA6 A;  4OND A;  1KB4 A;  5CBZ A;  1DSZ B;  2GAT A;  2EBL A;  3DZU D;  3E00 A;  4CN3 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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