1L9LA

Granulysin from human cytolytic t lymphocytes
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
74
structure length
74
Chain Sequence
GRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVIQGLVAGETAQQICEDLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Granulysin Crystal Structure and a Structure-Derived Lytic Mechanism
pubmed doi rcsb
molecule keywords Granulysin
molecule tags Antimicrobial protein
source organism Homo sapiens
total genus 27
structure length 74
sequence length 74
ec nomenclature
pdb deposition date 2002-03-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.225.10 Mainly Alpha Orthogonal Bundle NK-Lysin Saposin-like 1l9lA00
2W50A 4UEXA 4DDJA 2RB3A 1N69A 3S64A 1QDMA 3BQPA 2JSAA 3BQQA 2QYPA 4BITA 1NKLA 2R0RA 2DOBA 2LPNA 2JS9A 2RQYA 2R1QA 2W51A 2GTGA 1M12A 3S63A 4V2OA 3RFIA 2KVDA 1OF9A 1L9LA 2Z9AA 1SN6A
chains in the Genus database with same CATH superfamily
2W50A 4UEXA 4DDJA 2RB3A 1N69A 3S64A 1QDMA 3BQPA 3EUKE 2JSAA 3BQQA 2QYPA 4BITA 1NKLA 2R0RA 3EUJB 2DOBA 2LPNA 2JS9A 2RQYA 2R1QA 2W51A 2GTGA 1M12A 3S63A 4V2OA 3RFIA 2KVDA 1OF9A 1L9LA 2JQ3A 3CJLA 2Z9AA 1SN6A
chains in the Genus database with same CATH topology
2W50A 4UEXA 4DDJA 2RB3A 1N69A 3S64A 1QDMA 3BQPA 2JSAA 3BQQA 2QYPA 4BITA 1NKLA 2R0RA 2DOBA 2LPNA 2JS9A 2RQYA 2R1QA 2W51A 2GTGA 1M12A 3S63A 4V2OA 3RFIA 2KVDA 1OF9A 1L9LA 2Z9AA 1SN6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W50 A;  4UEX A;  4DDJ A;  2RB3 A;  1N69 A;  3S64 A;  1QDM A;  3BQP A;  2JSA A;  3BQQ A;  2QYP A;  4BIT A;  1NKL A;  2R0R A;  2DOB A;  2LPN A;  2JS9 A;  2RQY A;  2R1Q A;  2W51 A;  2GTG A;  1M12 A;  3S63 A;  4V2O A;  3RFI A;  2KVD A;  1OF9 A;  1L9L A;  2Z9A A;  1SN6 A; 
#chains in the Genus database with same CATH topology
 2W50 A;  4UEX A;  4DDJ A;  2RB3 A;  1N69 A;  3S64 A;  1QDM A;  3BQP A;  3EUK E;  2JSA A;  3BQQ A;  2QYP A;  4BIT A;  1NKL A;  2R0R A;  3EUJ B;  2DOB A;  2LPN A;  2JS9 A;  2RQY A;  2R1Q A;  2W51 A;  2GTG A;  1M12 A;  3S63 A;  4V2O A;  3RFI A;  2KVD A;  1OF9 A;  1L9L A;  2JQ3 A;  3CJL A;  2Z9A A;  1SN6 A; 
#chains in the Genus database with same CATH homology
 2W50 A;  4UEX A;  4DDJ A;  2RB3 A;  1N69 A;  3S64 A;  1QDM A;  3BQP A;  2JSA A;  3BQQ A;  2QYP A;  4BIT A;  1NKL A;  2R0R A;  2DOB A;  2LPN A;  2JS9 A;  2RQY A;  2R1Q A;  2W51 A;  2GTG A;  1M12 A;  3S63 A;  4V2O A;  3RFI A;  2KVD A;  1OF9 A;  1L9L A;  2Z9A A;  1SN6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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