1L9LA

Granulysin from human cytolytic t lymphocytes
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
74
structure length
74
Chain Sequence
GRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVIQGLVAGETAQQICEDLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Granulysin Crystal Structure and a Structure-Derived Lytic Mechanism
pubmed doi rcsb
molecule keywords Granulysin
molecule tags Antimicrobial protein
source organism Homo sapiens
total genus 27
structure length 74
sequence length 74
ec nomenclature
pdb deposition date 2002-03-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.225.10 Mainly Alpha Orthogonal Bundle NK-Lysin Saposin-like 1l9lA00
4DDJA 2LPNA 2Z9AA 2JSAA 1NKLA 1L9LA 1QDMA 4UEXA 2RB3A 1N69A 4BITA 2KVDA 1OF9A 2R0RA 2GTGA 2QYPA 3BQPA 4V2OA 3S63A 3S64A 2W50A 1SN6A 1M12A 2JS9A 2R1QA 2RQYA 2W51A 3BQQA 3RFIA 2DOBA
chains in the Genus database with same CATH superfamily
3EUJB 4DDJA 2LPNA 2Z9AA 2JSAA 1NKLA 1L9LA 1QDMA 4UEXA 2RB3A 1N69A 3CJLA 2JQ3A 3EUKE 4BITA 2KVDA 1OF9A 2R0RA 2GTGA 2QYPA 3BQPA 4V2OA 3S63A 3S64A 2W50A 1SN6A 1M12A 2JS9A 2R1QA 2RQYA 2W51A 3BQQA 3RFIA 2DOBA
chains in the Genus database with same CATH topology
4DDJA 2LPNA 2Z9AA 2JSAA 1NKLA 1L9LA 1QDMA 4UEXA 2RB3A 1N69A 4BITA 2KVDA 1OF9A 2R0RA 2GTGA 2QYPA 3BQPA 4V2OA 3S63A 3S64A 2W50A 1SN6A 1M12A 2JS9A 2R1QA 2RQYA 2W51A 3BQQA 3RFIA 2DOBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DDJ A;  2LPN A;  2Z9A A;  2JSA A;  1NKL A;  1L9L A;  1QDM A;  4UEX A;  2RB3 A;  1N69 A;  4BIT A;  2KVD A;  1OF9 A;  2R0R A;  2GTG A;  2QYP A;  3BQP A;  4V2O A;  3S63 A;  3S64 A;  2W50 A;  1SN6 A;  1M12 A;  2JS9 A;  2R1Q A;  2RQY A;  2W51 A;  3BQQ A;  3RFI A;  2DOB A; 
#chains in the Genus database with same CATH topology
 3EUJ B;  4DDJ A;  2LPN A;  2Z9A A;  2JSA A;  1NKL A;  1L9L A;  1QDM A;  4UEX A;  2RB3 A;  1N69 A;  3CJL A;  2JQ3 A;  3EUK E;  4BIT A;  2KVD A;  1OF9 A;  2R0R A;  2GTG A;  2QYP A;  3BQP A;  4V2O A;  3S63 A;  3S64 A;  2W50 A;  1SN6 A;  1M12 A;  2JS9 A;  2R1Q A;  2RQY A;  2W51 A;  3BQQ A;  3RFI A;  2DOB A; 
#chains in the Genus database with same CATH homology
 4DDJ A;  2LPN A;  2Z9A A;  2JSA A;  1NKL A;  1L9L A;  1QDM A;  4UEX A;  2RB3 A;  1N69 A;  4BIT A;  2KVD A;  1OF9 A;  2R0R A;  2GTG A;  2QYP A;  3BQP A;  4V2O A;  3S63 A;  3S64 A;  2W50 A;  1SN6 A;  1M12 A;  2JS9 A;  2R1Q A;  2RQY A;  2W51 A;  3BQQ A;  3RFI A;  2DOB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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