2W50A

N-terminal domain of human conserved dopamine neurotrophic factor (cdnf)
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
97
structure length
97
Chain Sequence
ADCEVCKEFLNRFYKSLIDRGVNFSLDTIEKELISFCLDTKGKENRLCYYLGATKDAATKILSEVTRPMSVHMPAMKICEKLKKLDSQICELKYEKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone
molecule keywords ARMET-LIKE PROTEIN 1
publication title The Structure of the Conserved Neurotrophic Factors Manf and Cdnf Explains Why They are Bifunctional.
pubmed doi rcsb
source organism Homo sapiens
total genus 35
structure length 97
sequence length 97
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-12-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.225.10 Mainly Alpha Orthogonal Bundle NK-Lysin Saposin-like 2w50A00
1NKLA 1N69A 2QYPA 1L9LA 3RFIA 2R0RA 4DDJA 4UEXA 3S64A 4BITA 2GTGA 2JSAA 2W50A 2RQYA 2DOBA 2W51A 2RB3A 2Z9AA 4V2OA 3BQPA 1SN6A 2JS9A 3S63A 3BQQA 1OF9A 1M12A 2R1QA 2LPNA 2KVDA 1QDMA
chains in the Genus database with same CATH superfamily
1NKLA 1N69A 2QYPA 1L9LA 3RFIA 2R0RA 4DDJA 4UEXA 3S64A 4BITA 2GTGA 2JSAA 2W50A 2RQYA 2DOBA 2W51A 2RB3A 2Z9AA 4V2OA 3BQPA 1SN6A 2JS9A 3S63A 3BQQA 1OF9A 1M12A 3EUKE 3EUJB 2R1QA 2LPNA 3CJLA 2KVDA 1QDMA 2JQ3A
chains in the Genus database with same CATH topology
1NKLA 1N69A 2QYPA 1L9LA 3RFIA 2R0RA 4DDJA 4UEXA 3S64A 4BITA 2GTGA 2JSAA 2W50A 2RQYA 2DOBA 2W51A 2RB3A 2Z9AA 4V2OA 3BQPA 1SN6A 2JS9A 3S63A 3BQQA 1OF9A 1M12A 2R1QA 2LPNA 2KVDA 1QDMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NKL A;  1N69 A;  2QYP A;  1L9L A;  3RFI A;  2R0R A;  4DDJ A;  4UEX A;  3S64 A;  4BIT A;  2GTG A;  2JSA A;  2W50 A;  2RQY A;  2DOB A;  2W51 A;  2RB3 A;  2Z9A A;  4V2O A;  3BQP A;  1SN6 A;  2JS9 A;  3S63 A;  3BQQ A;  1OF9 A;  1M12 A;  2R1Q A;  2LPN A;  2KVD A;  1QDM A; 
#chains in the Genus database with same CATH topology
 1NKL A;  1N69 A;  2QYP A;  1L9L A;  3RFI A;  2R0R A;  4DDJ A;  4UEX A;  3S64 A;  4BIT A;  2GTG A;  2JSA A;  2W50 A;  2RQY A;  2DOB A;  2W51 A;  2RB3 A;  2Z9A A;  4V2O A;  3BQP A;  1SN6 A;  2JS9 A;  3S63 A;  3BQQ A;  1OF9 A;  1M12 A;  3EUK E;  3EUJ B;  2R1Q A;  2LPN A;  3CJL A;  2KVD A;  1QDM A;  2JQ3 A; 
#chains in the Genus database with same CATH homology
 1NKL A;  1N69 A;  2QYP A;  1L9L A;  3RFI A;  2R0R A;  4DDJ A;  4UEX A;  3S64 A;  4BIT A;  2GTG A;  2JSA A;  2W50 A;  2RQY A;  2DOB A;  2W51 A;  2RB3 A;  2Z9A A;  4V2O A;  3BQP A;  1SN6 A;  2JS9 A;  3S63 A;  3BQQ A;  1OF9 A;  1M12 A;  2R1Q A;  2LPN A;  2KVD A;  1QDM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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