2QYPA

Orthorhombic crystal structure of human saposin c dimer in open conformation
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
78
structure length
78
Chain Sequence
SDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lipid binding protein
molecule keywords Proactivator polypeptide
publication title Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
pubmed doi rcsb
source organism Homo sapiens
total genus 21
structure length 78
sequence length 78
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03489 SapB_2 Saposin-like type B, region 2
A PF05184 SapB_1 Saposin-like type B, region 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.225.10 Mainly Alpha Orthogonal Bundle NK-Lysin Saposin-like 2qypA00
4BITA 2RQYA 2RB3A 2KVDA 4UEXA 3S64A 1QDMA 2W51A 1OF9A 1M12A 2GTGA 3RFIA 2JSAA 2W50A 3S63A 1L9LA 2LPNA 2JS9A 1NKLA 3BQPA 2DOBA 4DDJA 1N69A 2QYPA 4V2OA 2R0RA 3BQQA 2R1QA 2Z9AA 1SN6A
chains in the Genus database with same CATH superfamily
4BITA 2RQYA 2RB3A 2KVDA 4UEXA 3S64A 1QDMA 1OF9A 2W51A 1M12A 2GTGA 3RFIA 2JSAA 2W50A 3S63A 1L9LA 2LPNA 3EUJB 2JS9A 3CJLA 1NKLA 3BQPA 3EUKE 2JQ3A 2DOBA 4DDJA 1N69A 2QYPA 4V2OA 2R0RA 3BQQA 2R1QA 2Z9AA 1SN6A
chains in the Genus database with same CATH topology
4BITA 2RQYA 2RB3A 2KVDA 4UEXA 3S64A 1QDMA 2W51A 1OF9A 1M12A 2GTGA 3RFIA 2JSAA 2W50A 3S63A 1L9LA 2LPNA 2JS9A 1NKLA 3BQPA 2DOBA 4DDJA 1N69A 2QYPA 4V2OA 2R0RA 3BQQA 2R1QA 2Z9AA 1SN6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BIT A;  2RQY A;  2RB3 A;  2KVD A;  4UEX A;  3S64 A;  1QDM A;  2W51 A;  1OF9 A;  1M12 A;  2GTG A;  3RFI A;  2JSA A;  2W50 A;  3S63 A;  1L9L A;  2LPN A;  2JS9 A;  1NKL A;  3BQP A;  2DOB A;  4DDJ A;  1N69 A;  2QYP A;  4V2O A;  2R0R A;  3BQQ A;  2R1Q A;  2Z9A A;  1SN6 A; 
#chains in the Genus database with same CATH topology
 4BIT A;  2RQY A;  2RB3 A;  2KVD A;  4UEX A;  3S64 A;  1QDM A;  1OF9 A;  2W51 A;  1M12 A;  2GTG A;  3RFI A;  2JSA A;  2W50 A;  3S63 A;  1L9L A;  2LPN A;  3EUJ B;  2JS9 A;  3CJL A;  1NKL A;  3BQP A;  3EUK E;  2JQ3 A;  2DOB A;  4DDJ A;  1N69 A;  2QYP A;  4V2O A;  2R0R A;  3BQQ A;  2R1Q A;  2Z9A A;  1SN6 A; 
#chains in the Genus database with same CATH homology
 4BIT A;  2RQY A;  2RB3 A;  2KVD A;  4UEX A;  3S64 A;  1QDM A;  2W51 A;  1OF9 A;  1M12 A;  2GTG A;  3RFI A;  2JSA A;  2W50 A;  3S63 A;  1L9L A;  2LPN A;  2JS9 A;  1NKL A;  3BQP A;  2DOB A;  4DDJ A;  1N69 A;  2QYP A;  4V2O A;  2R0R A;  3BQQ A;  2R1Q A;  2Z9A A;  1SN6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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