1LTGA

The arg7lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the a subunit
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
185
structure length
175
Chain Sequence
RLYKADSRPPDEIKRSGGLMPRGHNEYFDRGTQMNINLYDHARDGYVSTSLSLRSAHLAGQSILSGYSTYYIYVIATAPNMFNVNDVLGVYSPHPYEQEVSALGGIPYSQIYGWYRVNFGVIDERLHRNREYRDRYYRNLNIAPAEDGYRLAGFPPDHQAWREEPWIHHAPQGCG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit.
pubmed doi rcsb
molecule keywords HEAT-LABILE ENTEROTOXIN
molecule tags Enterotoxin
source organism Escherichia coli
total genus 46
structure length 175
sequence length 185
ec nomenclature
pdb deposition date 1995-06-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.210.10 Alpha Beta Alpha-Beta Complex Heat-Labile Enterotoxin; Chain A Heat-Labile Enterotoxin, subunit A 1ltgA00
2CB6A 1LT4A 2CB4A 1PRTA 2VSAA 4Z9CA 1LT3A 1LTTA 1LTAA 1TIIA 2A5DB 1S5EA 1S5FA 1S5BA 2A5GB 2A5FB 1LTGA 1LTBA 1HTLA 1S5DA 1BCPA 1LTIA 1PTOA 1XTCA 4K6LG 1LTSA 1S5CA 2VSEA
chains in the Genus database with same CATH superfamily
2CB6A 1LT4A 2CB4A 1PRTA 2VSAA 4Z9CA 1LT3A 1LTTA 1LTAA 1TIIA 2A5DB 1S5EA 1S5FA 1S5BA 2A5GB 2A5FB 1LTGA 1LTBA 1HTLA 1S5DA 1BCPA 1LTIA 1PTOA 1XTCA 4K6LG 1LTSA 1S5CA 2VSEA
chains in the Genus database with same CATH topology
2CB6A 1LT4A 2CB4A 1PRTA 2VSAA 4Z9CA 1LT3A 1LTTA 1LTAA 1TIIA 2A5DB 1S5EA 1S5FA 1S5BA 2A5GB 2A5FB 1LTGA 1LTBA 1HTLA 1S5DA 1BCPA 1LTIA 1PTOA 1XTCA 4K6LG 1LTSA 1S5CA 2VSEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CB6 A;  1LT4 A;  2CB4 A;  1PRT A;  2VSA A;  4Z9C A;  1LT3 A;  1LTT A;  1LTA A;  1TII A;  2A5D B;  1S5E A;  1S5F A;  1S5B A;  2A5G B;  2A5F B;  1LTG A;  1LTB A;  1HTL A;  1S5D A;  1BCP A;  1LTI A;  1PTO A;  1XTC A;  4K6L G;  1LTS A;  1S5C A;  2VSE A; 
#chains in the Genus database with same CATH topology
 2CB6 A;  1LT4 A;  2CB4 A;  1PRT A;  2VSA A;  4Z9C A;  1LT3 A;  1LTT A;  1LTA A;  1TII A;  2A5D B;  1S5E A;  1S5F A;  1S5B A;  2A5G B;  2A5F B;  1LTG A;  1LTB A;  1HTL A;  1S5D A;  1BCP A;  1LTI A;  1PTO A;  1XTC A;  4K6L G;  1LTS A;  1S5C A;  2VSE A; 
#chains in the Genus database with same CATH homology
 2CB6 A;  1LT4 A;  2CB4 A;  1PRT A;  2VSA A;  4Z9C A;  1LT3 A;  1LTT A;  1LTA A;  1TII A;  2A5D B;  1S5E A;  1S5F A;  1S5B A;  2A5G B;  2A5F B;  1LTG A;  1LTB A;  1HTL A;  1S5D A;  1BCP A;  1LTI A;  1PTO A;  1XTC A;  4K6L G;  1LTS A;  1S5C A;  2VSE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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