1S5DA

Cholera holotoxin with an a-subunit y30s mutation, crystal form 2
Total Genus 65
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
235
structure length
218
Chain Sequence
NDDKLYRADSRPPDEIKQSGGLMPRGQSQMNINLYDHARGTTGFVRHDDGYVSTSISLRSAHLVGQTILSGHSTYYIYVIATAPNMFNVNDVLGAYSPHPDEQEVSALGGIPYSQIYGWYRVHFGVLDEQLHRNRGYRDRYYSNLDIAPAADGYGLAGFPPEHRAWREEPWIHHAPPGCGTCDEKTQSLGVKFLDEYQSKVKRQIFSGYQSDIDTHNR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transferase,toxin
molecule keywords Cholera enterotoxin, A chain
publication title Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
pubmed doi rcsb
source organism Vibrio cholerae
total genus 65
structure length 218
sequence length 235
ec nomenclature ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date 2004-01-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.210.10 Alpha Beta Alpha-Beta Complex Heat-Labile Enterotoxin; Chain A Heat-Labile Enterotoxin, subunit A 1s5dA00
1LTGA 4Z9CA 1S5EA 2CB4A 2VSAA 1LTIA 2CB6A 2VSEA 1PTOA 1BCPA 1LTTA 4K6LG 2A5DB 1S5CA 1S5BA 1LTAA 1LT4A 1S5FA 1XTCA 2A5FB 1LTSA 1HTLA 1LT3A 1S5DA 1PRTA 2A5GB 1LTBA 1TIIA
chains in the Genus database with same CATH superfamily
1LTGA 4Z9CA 1S5EA 2CB4A 2VSAA 1LTIA 2CB6A 2VSEA 1PTOA 1BCPA 1LTTA 4K6LG 2A5DB 1S5CA 1S5BA 1LTAA 1LT4A 1S5FA 1XTCA 2A5FB 1LTSA 1HTLA 1LT3A 1S5DA 1PRTA 2A5GB 1LTBA 1TIIA
chains in the Genus database with same CATH topology
1LTGA 4Z9CA 1S5EA 2CB4A 2VSAA 1LTIA 2CB6A 2VSEA 1PTOA 1BCPA 1LTTA 4K6LG 2A5DB 1S5CA 1S5BA 1LTAA 1LT4A 1S5FA 1XTCA 2A5FB 1LTSA 1HTLA 1LT3A 1S5DA 1PRTA 2A5GB 1LTBA 1TIIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LTG A;  4Z9C A;  1S5E A;  2CB4 A;  2VSA A;  1LTI A;  2CB6 A;  2VSE A;  1PTO A;  1BCP A;  1LTT A;  4K6L G;  2A5D B;  1S5C A;  1S5B A;  1LTA A;  1LT4 A;  1S5F A;  1XTC A;  2A5F B;  1LTS A;  1HTL A;  1LT3 A;  1S5D A;  1PRT A;  2A5G B;  1LTB A;  1TII A; 
#chains in the Genus database with same CATH topology
 1LTG A;  4Z9C A;  1S5E A;  2CB4 A;  2VSA A;  1LTI A;  2CB6 A;  2VSE A;  1PTO A;  1BCP A;  1LTT A;  4K6L G;  2A5D B;  1S5C A;  1S5B A;  1LTA A;  1LT4 A;  1S5F A;  1XTC A;  2A5F B;  1LTS A;  1HTL A;  1LT3 A;  1S5D A;  1PRT A;  2A5G B;  1LTB A;  1TII A; 
#chains in the Genus database with same CATH homology
 1LTG A;  4Z9C A;  1S5E A;  2CB4 A;  2VSA A;  1LTI A;  2CB6 A;  2VSE A;  1PTO A;  1BCP A;  1LTT A;  4K6L G;  2A5D B;  1S5C A;  1S5B A;  1LTA A;  1LT4 A;  1S5F A;  1XTC A;  2A5F B;  1LTS A;  1HTL A;  1LT3 A;  1S5D A;  1PRT A;  2A5G B;  1LTB A;  1TII A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...