2A5GB

Cholera toxin a1 subunit bound to arf6(q67l)
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
187
structure length
185
Chain Sequence
NDDKLYRADSRPPDEIKQSGGLMPRGQSEYFDRGTQMNINLYDHARGTQFVRHDDGYVSTSISLRSAHLVGQTILSGHSTYYIYVIATAPNMFNVNDVLGAYSPHPDDQDVSALGGIPYSQIYGWYRVHFGVLDEQLHRNRGYRDRYYSNLDIAPAADGYGLAGFPPEHRAWREEPWIHHAPPGS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Protein transport/transferase
molecule keywords ADP-ribosylation factor 6
publication title Structural basis for the activation of cholera toxin by human ARF6-GTP.
pubmed doi rcsb
source organism Homo sapiens
total genus 56
structure length 185
sequence length 187
ec nomenclature ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date 2005-06-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.210.10 Alpha Beta Alpha-Beta Complex Heat-Labile Enterotoxin; Chain A Heat-Labile Enterotoxin, subunit A 2a5gB00
1XTCA 1LTTA 1LTIA 1LTAA 2VSAA 1S5CA 2A5GB 1LT3A 4K6LG 2A5DB 1HTLA 1S5BA 4Z9CA 2VSEA 2CB4A 1S5EA 1TIIA 1PRTA 1PTOA 1LTGA 2A5FB 1LT4A 2CB6A 1LTBA 1BCPA 1S5FA 1S5DA 1LTSA
chains in the Genus database with same CATH superfamily
1XTCA 1LTTA 1LTIA 1LTAA 2VSAA 1S5CA 2A5GB 1LT3A 4K6LG 2A5DB 1HTLA 1S5BA 4Z9CA 2VSEA 2CB4A 1S5EA 1TIIA 1PRTA 1PTOA 1LTGA 2A5FB 1LT4A 2CB6A 1LTBA 1BCPA 1S5FA 1S5DA 1LTSA
chains in the Genus database with same CATH topology
1XTCA 1LTTA 1LTIA 1LTAA 2VSAA 1S5CA 2A5GB 1LT3A 4K6LG 2A5DB 1HTLA 1S5BA 4Z9CA 2VSEA 2CB4A 1S5EA 1TIIA 1PRTA 1PTOA 1LTGA 2A5FB 1LT4A 2CB6A 1LTBA 1BCPA 1S5FA 1S5DA 1LTSA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1XTC A;  1LTT A;  1LTI A;  1LTA A;  2VSA A;  1S5C A;  2A5G B;  1LT3 A;  4K6L G;  2A5D B;  1HTL A;  1S5B A;  4Z9C A;  2VSE A;  2CB4 A;  1S5E A;  1TII A;  1PRT A;  1PTO A;  1LTG A;  2A5F B;  1LT4 A;  2CB6 A;  1LTB A;  1BCP A;  1S5F A;  1S5D A;  1LTS A; 
#chains in the Genus database with same CATH topology
 1XTC A;  1LTT A;  1LTI A;  1LTA A;  2VSA A;  1S5C A;  2A5G B;  1LT3 A;  4K6L G;  2A5D B;  1HTL A;  1S5B A;  4Z9C A;  2VSE A;  2CB4 A;  1S5E A;  1TII A;  1PRT A;  1PTO A;  1LTG A;  2A5F B;  1LT4 A;  2CB6 A;  1LTB A;  1BCP A;  1S5F A;  1S5D A;  1LTS A; 
#chains in the Genus database with same CATH homology
 1XTC A;  1LTT A;  1LTI A;  1LTA A;  2VSA A;  1S5C A;  2A5G B;  1LT3 A;  4K6L G;  2A5D B;  1HTL A;  1S5B A;  4Z9C A;  2VSE A;  2CB4 A;  1S5E A;  1TII A;  1PRT A;  1PTO A;  1LTG A;  2A5F B;  1LT4 A;  2CB6 A;  1LTB A;  1BCP A;  1S5F A;  1S5D A;  1LTS A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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