The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
99
|
sequence length |
338
|
structure length |
332
|
Chain Sequence |
ERRYLPLSQARKSGFQMDWLSEPHPVKPTFIGTQVFEEYDLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKGEARKVYDDAHNMLNTLISQKKLRARGVVGFWPAQSIQDDIHLYAEAAVPQAAEPIATFYGLRQQAENSTEPYYCLSDFIAPLHSGIRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLDVADLRRLRYKGIRPAPGYPSQPDHTEKLTMWRLADIEQSTGIRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQVEDYALRKNISVAEVEKWLGPILGYD
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Crystal structure and solution characterization of the activation domain of human methionine synthase
pubmed doi rcsb |
| molecule tags |
Transferase
|
| source organism |
Homo sapiens
|
| molecule keywords |
Methionine synthase
|
| total genus |
99
|
| structure length |
332
|
| sequence length |
338
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
2.1.1.13: Methionine synthase. |
| pdb deposition date | 2006-11-30 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02965 | Met_synt_B12 | Vitamin B12 dependent methionine synthase, activation domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Cobalamin-dependent Methionine Synthase; domain 2 | Cobalamin-dependent Methionine Synthase, domain 2 | ||
| Alpha Beta | Roll | Cobalamin-dependent Methionine Synthase; domain 1 | Vitamin B12-dependent methionine synthase, activation domain |
#chains in the Genus database with same CATH superfamily 2O2K A; 3BUL A; 1MSK A; 3IVA A; 1K7Y A; 1K98 A; 3IV9 A; #chains in the Genus database with same CATH topology 3TPQ M; 2O2K A; 2YJF M; 3BUL A; 1MSK A; 3IVA A; 1K7Y A; 1K98 A; 3IV9 A; #chains in the Genus database with same CATH homology 2O2K A; 3BUL A; 1MSK A; 3IVA A; 1K7Y A; 1K98 A; 3IV9 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
