2R0RA

Crystal structure of human saposin d variant sapd k9e
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
77
structure length
77
Chain Sequence
GFCEVCEKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGACP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
pubmed doi rcsb
molecule tags Lipid binding protein
source organism Homo sapiens
molecule keywords Proactivator polypeptide
total genus 23
structure length 77
sequence length 77
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03489 SapB_2 Saposin-like type B, region 2
A PF05184 SapB_1 Saposin-like type B, region 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.225.10 Mainly Alpha Orthogonal Bundle NK-Lysin Saposin-like 2r0rA00
3BQPA 2RQYA 2W50A 2R1QA 1SN6A 1NKLA 1N69A 2JS9A 3S64A 2QYPA 2RB3A 2KVDA 4BITA 2DOBA 2LPNA 2GTGA 1M12A 2R0RA 4UEXA 4DDJA 2W51A 1OF9A 4V2OA 1L9LA 1QDMA 3RFIA 3BQQA 3S63A 2Z9AA 2JSAA
chains in the Genus database with same CATH superfamily
3BQPA 2RQYA 2W50A 2R1QA 1SN6A 1NKLA 1N69A 2JS9A 3EUJB 3S64A 2QYPA 2RB3A 2KVDA 4BITA 2DOBA 2LPNA 3EUKE 2GTGA 1M12A 2R0RA 4UEXA 4DDJA 2W51A 1OF9A 4V2OA 1L9LA 1QDMA 2JQ3A 3RFIA 3BQQA 3S63A 2Z9AA 3CJLA 2JSAA
chains in the Genus database with same CATH topology
3BQPA 2RQYA 2W50A 2R1QA 1SN6A 1NKLA 1N69A 2JS9A 3S64A 2QYPA 2RB3A 2KVDA 4BITA 2DOBA 2LPNA 2GTGA 1M12A 2R0RA 4UEXA 4DDJA 2W51A 1OF9A 4V2OA 1L9LA 1QDMA 3RFIA 3BQQA 3S63A 2Z9AA 2JSAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BQP A;  2RQY A;  2W50 A;  2R1Q A;  1SN6 A;  1NKL A;  1N69 A;  2JS9 A;  3S64 A;  2QYP A;  2RB3 A;  2KVD A;  4BIT A;  2DOB A;  2LPN A;  2GTG A;  1M12 A;  2R0R A;  4UEX A;  4DDJ A;  2W51 A;  1OF9 A;  4V2O A;  1L9L A;  1QDM A;  3RFI A;  3BQQ A;  3S63 A;  2Z9A A;  2JSA A; 
#chains in the Genus database with same CATH topology
 3BQP A;  2RQY A;  2W50 A;  2R1Q A;  1SN6 A;  1NKL A;  1N69 A;  2JS9 A;  3EUJ B;  3S64 A;  2QYP A;  2RB3 A;  2KVD A;  4BIT A;  2DOB A;  2LPN A;  3EUK E;  2GTG A;  1M12 A;  2R0R A;  4UEX A;  4DDJ A;  2W51 A;  1OF9 A;  4V2O A;  1L9L A;  1QDM A;  2JQ3 A;  3RFI A;  3BQQ A;  3S63 A;  2Z9A A;  3CJL A;  2JSA A; 
#chains in the Genus database with same CATH homology
 3BQP A;  2RQY A;  2W50 A;  2R1Q A;  1SN6 A;  1NKL A;  1N69 A;  2JS9 A;  3S64 A;  2QYP A;  2RB3 A;  2KVD A;  4BIT A;  2DOB A;  2LPN A;  2GTG A;  1M12 A;  2R0R A;  4UEX A;  4DDJ A;  2W51 A;  1OF9 A;  4V2O A;  1L9L A;  1QDM A;  3RFI A;  3BQQ A;  3S63 A;  2Z9A A;  2JSA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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