2R1QA

Crystal structure of iodinated human saposin d in space group c2221
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
78
structure length
77
Chain Sequence
AGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEEPVLIEILVEVMDPSFVCLKIGACP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
pubmed doi rcsb
molecule keywords Proactivator polypeptide
molecule tags Lipid binding protein
source organism Homo sapiens
total genus 21
structure length 77
sequence length 78
ec nomenclature
pdb deposition date 2007-08-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03489 SapB_2 Saposin-like type B, region 2
A PF05184 SapB_1 Saposin-like type B, region 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.225.10 Mainly Alpha Orthogonal Bundle NK-Lysin Saposin-like 2r1qA00
2LPNA 1N69A 2DOBA 1NKLA 1OF9A 2RQYA 3RFIA 2W50A 3BQQA 2W51A 2R1QA 2KVDA 1SN6A 4V2OA 2QYPA 2JSAA 3S63A 2R0RA 2RB3A 2JS9A 1QDMA 2Z9AA 4BITA 4DDJA 2GTGA 3S64A 1M12A 4UEXA 1L9LA 3BQPA
chains in the Genus database with same CATH superfamily
2LPNA 1N69A 2JQ3A 2DOBA 1NKLA 1OF9A 2RQYA 3RFIA 2W50A 3BQQA 2W51A 2R1QA 3EUKE 2KVDA 1SN6A 4V2OA 2QYPA 2JSAA 3S63A 2R0RA 2RB3A 2JS9A 1QDMA 2Z9AA 4BITA 4DDJA 2GTGA 3S64A 1M12A 3CJLA 3EUJB 4UEXA 1L9LA 3BQPA
chains in the Genus database with same CATH topology
2LPNA 1N69A 2DOBA 1NKLA 1OF9A 2RQYA 3RFIA 2W50A 3BQQA 2W51A 2R1QA 2KVDA 1SN6A 4V2OA 2QYPA 2JSAA 3S63A 2R0RA 2RB3A 2JS9A 1QDMA 2Z9AA 4BITA 4DDJA 2GTGA 3S64A 1M12A 4UEXA 1L9LA 3BQPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LPN A;  1N69 A;  2DOB A;  1NKL A;  1OF9 A;  2RQY A;  3RFI A;  2W50 A;  3BQQ A;  2W51 A;  2R1Q A;  2KVD A;  1SN6 A;  4V2O A;  2QYP A;  2JSA A;  3S63 A;  2R0R A;  2RB3 A;  2JS9 A;  1QDM A;  2Z9A A;  4BIT A;  4DDJ A;  2GTG A;  3S64 A;  1M12 A;  4UEX A;  1L9L A;  3BQP A; 
#chains in the Genus database with same CATH topology
 2LPN A;  1N69 A;  2JQ3 A;  2DOB A;  1NKL A;  1OF9 A;  2RQY A;  3RFI A;  2W50 A;  3BQQ A;  2W51 A;  2R1Q A;  3EUK E;  2KVD A;  1SN6 A;  4V2O A;  2QYP A;  2JSA A;  3S63 A;  2R0R A;  2RB3 A;  2JS9 A;  1QDM A;  2Z9A A;  4BIT A;  4DDJ A;  2GTG A;  3S64 A;  1M12 A;  3CJL A;  3EUJ B;  4UEX A;  1L9L A;  3BQP A; 
#chains in the Genus database with same CATH homology
 2LPN A;  1N69 A;  2DOB A;  1NKL A;  1OF9 A;  2RQY A;  3RFI A;  2W50 A;  3BQQ A;  2W51 A;  2R1Q A;  2KVD A;  1SN6 A;  4V2O A;  2QYP A;  2JSA A;  3S63 A;  2R0R A;  2RB3 A;  2JS9 A;  1QDM A;  2Z9A A;  4BIT A;  4DDJ A;  2GTG A;  3S64 A;  1M12 A;  4UEX A;  1L9L A;  3BQP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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