2RB3A

Crystal structure of human saposin d
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
79
structure length
79
Chain Sequence
AGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGACPS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
pubmed doi rcsb
molecule tags Lipid binding protein
source organism Homo sapiens
molecule keywords Proactivator polypeptide
total genus 24
structure length 79
sequence length 79
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2007-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03489 SapB_2 Saposin-like type B, region 2
A PF05184 SapB_1 Saposin-like type B, region 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.225.10 Mainly Alpha Orthogonal Bundle NK-Lysin Saposin-like 2rb3A00
1L9LA 2W51A 2RQYA 3S63A 1OF9A 4BITA 2GTGA 1N69A 4UEXA 2JS9A 1QDMA 3BQQA 3BQPA 2Z9AA 1M12A 3RFIA 3S64A 2R1QA 1NKLA 4DDJA 2DOBA 2JSAA 2KVDA 1SN6A 2QYPA 4V2OA 2R0RA 2RB3A 2LPNA 2W50A
chains in the Genus database with same CATH superfamily
1L9LA 2W51A 2RQYA 3S63A 1OF9A 4BITA 3EUKE 2JQ3A 2GTGA 3EUJB 1N69A 4UEXA 2JS9A 1QDMA 3BQQA 3BQPA 2Z9AA 1M12A 3RFIA 3S64A 2R1QA 1NKLA 4DDJA 2DOBA 2JSAA 2KVDA 1SN6A 2QYPA 4V2OA 2R0RA 3CJLA 2RB3A 2LPNA 2W50A
chains in the Genus database with same CATH topology
1L9LA 2W51A 2RQYA 3S63A 1OF9A 4BITA 2GTGA 1N69A 4UEXA 2JS9A 1QDMA 3BQQA 3BQPA 2Z9AA 1M12A 3RFIA 3S64A 2R1QA 1NKLA 4DDJA 2DOBA 2JSAA 2KVDA 1SN6A 2QYPA 4V2OA 2R0RA 2RB3A 2LPNA 2W50A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1L9L A;  2W51 A;  2RQY A;  3S63 A;  1OF9 A;  4BIT A;  2GTG A;  1N69 A;  4UEX A;  2JS9 A;  1QDM A;  3BQQ A;  3BQP A;  2Z9A A;  1M12 A;  3RFI A;  3S64 A;  2R1Q A;  1NKL A;  4DDJ A;  2DOB A;  2JSA A;  2KVD A;  1SN6 A;  2QYP A;  4V2O A;  2R0R A;  2RB3 A;  2LPN A;  2W50 A; 
#chains in the Genus database with same CATH topology
 1L9L A;  2W51 A;  2RQY A;  3S63 A;  1OF9 A;  4BIT A;  3EUK E;  2JQ3 A;  2GTG A;  3EUJ B;  1N69 A;  4UEX A;  2JS9 A;  1QDM A;  3BQQ A;  3BQP A;  2Z9A A;  1M12 A;  3RFI A;  3S64 A;  2R1Q A;  1NKL A;  4DDJ A;  2DOB A;  2JSA A;  2KVD A;  1SN6 A;  2QYP A;  4V2O A;  2R0R A;  3CJL A;  2RB3 A;  2LPN A;  2W50 A; 
#chains in the Genus database with same CATH homology
 1L9L A;  2W51 A;  2RQY A;  3S63 A;  1OF9 A;  4BIT A;  2GTG A;  1N69 A;  4UEX A;  2JS9 A;  1QDM A;  3BQQ A;  3BQP A;  2Z9A A;  1M12 A;  3RFI A;  3S64 A;  2R1Q A;  1NKL A;  4DDJ A;  2DOB A;  2JSA A;  2KVD A;  1SN6 A;  2QYP A;  4V2O A;  2R0R A;  2RB3 A;  2LPN A;  2W50 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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