2W50A

N-terminal domain of human conserved dopamine neurotrophic factor (cdnf)
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
97
structure length
97
Chain Sequence
ADCEVCKEFLNRFYKSLIDRGVNFSLDTIEKELISFCLDTKGKENRLCYYLGATKDAATKILSEVTRPMSVHMPAMKICEKLKKLDSQICELKYEKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the Conserved Neurotrophic Factors Manf and Cdnf Explains Why They are Bifunctional.
pubmed doi rcsb
molecule tags Hormone
source organism Homo sapiens
molecule keywords ARMET-LIKE PROTEIN 1
total genus 35
structure length 97
sequence length 97
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-12-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.225.10 Mainly Alpha Orthogonal Bundle NK-Lysin Saposin-like 2w50A00
2LPNA 3S64A 3S63A 1SN6A 4BITA 1N69A 3BQQA 1M12A 2GTGA 4DDJA 4V2OA 2R0RA 2QYPA 2RB3A 2JSAA 1L9LA 2Z9AA 2DOBA 3BQPA 2JS9A 2KVDA 3RFIA 4UEXA 1OF9A 2R1QA 1QDMA 2W51A 1NKLA 2RQYA 2W50A
chains in the Genus database with same CATH superfamily
2LPNA 3S64A 3S63A 1SN6A 4BITA 3EUKE 1N69A 3BQQA 1M12A 2GTGA 4DDJA 4V2OA 2JQ3A 2R0RA 2QYPA 2RB3A 2JSAA 1L9LA 2Z9AA 3CJLA 2DOBA 3BQPA 2JS9A 2KVDA 3RFIA 4UEXA 1OF9A 3EUJB 2R1QA 1QDMA 2W51A 1NKLA 2RQYA 2W50A
chains in the Genus database with same CATH topology
2LPNA 3S64A 3S63A 1SN6A 4BITA 1N69A 3BQQA 1M12A 2GTGA 4DDJA 4V2OA 2R0RA 2QYPA 2RB3A 2JSAA 1L9LA 2Z9AA 2DOBA 3BQPA 2JS9A 2KVDA 3RFIA 4UEXA 1OF9A 2R1QA 1QDMA 2W51A 1NKLA 2RQYA 2W50A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LPN A;  3S64 A;  3S63 A;  1SN6 A;  4BIT A;  1N69 A;  3BQQ A;  1M12 A;  2GTG A;  4DDJ A;  4V2O A;  2R0R A;  2QYP A;  2RB3 A;  2JSA A;  1L9L A;  2Z9A A;  2DOB A;  3BQP A;  2JS9 A;  2KVD A;  3RFI A;  4UEX A;  1OF9 A;  2R1Q A;  1QDM A;  2W51 A;  1NKL A;  2RQY A;  2W50 A; 
#chains in the Genus database with same CATH topology
 2LPN A;  3S64 A;  3S63 A;  1SN6 A;  4BIT A;  3EUK E;  1N69 A;  3BQQ A;  1M12 A;  2GTG A;  4DDJ A;  4V2O A;  2JQ3 A;  2R0R A;  2QYP A;  2RB3 A;  2JSA A;  1L9L A;  2Z9A A;  3CJL A;  2DOB A;  3BQP A;  2JS9 A;  2KVD A;  3RFI A;  4UEX A;  1OF9 A;  3EUJ B;  2R1Q A;  1QDM A;  2W51 A;  1NKL A;  2RQY A;  2W50 A; 
#chains in the Genus database with same CATH homology
 2LPN A;  3S64 A;  3S63 A;  1SN6 A;  4BIT A;  1N69 A;  3BQQ A;  1M12 A;  2GTG A;  4DDJ A;  4V2O A;  2R0R A;  2QYP A;  2RB3 A;  2JSA A;  1L9L A;  2Z9A A;  2DOB A;  3BQP A;  2JS9 A;  2KVD A;  3RFI A;  4UEX A;  1OF9 A;  2R1Q A;  1QDM A;  2W51 A;  1NKL A;  2RQY A;  2W50 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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