3BSUA

Hybrid-binding domain of human rnase h1 in complex with 12-mer rna/dna
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
48
structure length
48
Chain Sequence
HMFYAVRRGRKTGVFLTWNECRAQVDRFPAARFKKFATEDEAWAFVRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD.
pubmed doi rcsb
molecule tags Hydrolase/rna/dna
source organism Homo sapiens
molecule keywords RNA (5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3')
total genus 15
structure length 48
sequence length 48
chains with identical sequence B, C, F, G, H
ec nomenclature ec 3.1.26.4: Ribonuclease H.
pdb deposition date 2007-12-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01693 Cauli_VI Caulimovirus viroplasmin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.970.10 Alpha Beta 3-Layer(aba) Sandwich Ribonuclease HI; Chain A Ribonuclease H1, N-terminal domain 3bsuA00
1QHKA 3BSUA
chains in the Genus database with same CATH superfamily
3DOAA 3I01M 5H3XA 1OAOC 3BSUA 1MJGM 2Z8YM 3PMQA 3GITA 3I04M 1QHKA 1RU3A 3BL4A
chains in the Genus database with same CATH topology
1QHKA 3BSUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QHK A;  3BSU A; 
#chains in the Genus database with same CATH topology
 3DOA A;  3I01 M;  5H3X A;  1OAO C;  3BSU A;  1MJG M;  2Z8Y M;  3PMQ A;  3GIT A;  3I04 M;  1QHK A;  1RU3 A;  3BL4 A; 
#chains in the Genus database with same CATH homology
 1QHK A;  3BSU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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