3X01A

Crystal structure of pip4kiibeta complex with amp
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
385
structure length
315
Chain Sequence
KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPEQYSKRFNEFMSNILT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
total genus 99
structure length 315
sequence length 385
chains with identical sequence B
ec nomenclature ec 2.7.1.149: 1-phosphatidylinositol-5-phosphate 4-kinase.
pdb deposition date 2014-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01504 PIP5K Phosphatidylinositol-4-phosphate 5-Kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.800.10 Alpha Beta 2-Layer Sandwich Phosphatidylinositol Phosphate Kinase II Beta Phosphatidylinositol Phosphate Kinase II Beta 3x01A01
3.30.810.10 Alpha Beta 2-Layer Sandwich Phosphatidylinositol Phosphate Kinase Iibeta; Chain: A, domain 2 2-Layer Sandwich 3x01A02
3X05A 3X03A 3X02A 5E3TA 3X09A 4TZ7A 3X08A 3X0CA 5E3UA 3X04A 1BO1A 3X0AA 2GK9A 3X01A 3X06A 3X0BA 3WZZA 5E3SA 3X07A 2YBXA
chains in the Genus database with same CATH superfamily
3X05A 3X03A 3X02A 5E3TA 3X09A 4TZ7A 3X08A 3X0CA 5E3UA 3X04A 1BO1A 3X0AA 2GK9A 3X01A 3X06A 3X0BA 3WZZA 5E3SA 3X07A 2YBXA
chains in the Genus database with same CATH topology
3X05A 3X03A 3X02A 5E3TA 3X09A 4TZ7A 3X08A 3X0CA 5E3UA 3X04A 1BO1A 3X0AA 2GK9A 3X01A 3X06A 3X0BA 3WZZA 5E3SA 3X07A 2YBXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X05 A;  3X03 A;  3X02 A;  5E3T A;  3X09 A;  4TZ7 A;  3X08 A;  3X0C A;  5E3U A;  3X04 A;  1BO1 A;  3X0A A;  2GK9 A;  3X01 A;  3X06 A;  3X0B A;  3WZZ A;  5E3S A;  3X07 A;  2YBX A; 
#chains in the Genus database with same CATH topology
 3X05 A;  3X03 A;  3X02 A;  5E3T A;  3X09 A;  4TZ7 A;  3X08 A;  3X0C A;  5E3U A;  3X04 A;  1BO1 A;  3X0A A;  2GK9 A;  3X01 A;  3X06 A;  3X0B A;  3WZZ A;  5E3S A;  3X07 A;  2YBX A; 
#chains in the Genus database with same CATH homology
 3X05 A;  3X03 A;  3X02 A;  5E3T A;  3X09 A;  4TZ7 A;  3X08 A;  3X0C A;  5E3U A;  3X04 A;  1BO1 A;  3X0A A;  2GK9 A;  3X01 A;  3X06 A;  3X0B A;  3WZZ A;  5E3S A;  3X07 A;  2YBX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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