4KGHA

Crystal structure of human splunc1 lacking the secretion signal sequence
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
212
structure length
193
Chain Sequence
SPTGLAGSLTNALSNGLLSGGLLGILENLPLLDILLGKVTSVIPGLNNVIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKLDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords BPI fold-containing family A member 1
total genus 39
structure length 193
sequence length 212
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 4kghA00
1BP1A 4KGOA 1EWFA 4EWSA 5I7KA 4F2AA 2OBDA 5I7LA 5I7JA 3ZPMA 4KGHA 4M4DA
chains in the Genus database with same CATH superfamily
1USUB 4F2AA 3N72A 4KGOA 3H4ZA 4EWSA 2OBDA 5I7JA 2RCKA 3AOSA 4KGHA 1BP1A 3AOTA 1USVB 3UV1A 5I7KA 2RQFA 3E8WA 3A1ZA 1EWFA 4G0SA 5I7LA 3L6IA 3ZPMA 3E8TA 4M4DA
chains in the Genus database with same CATH topology
1USUB 4F2AA 3N72A 4KGOA 3H4ZA 4EWSA 2OBDA 5I7JA 2RCKA 3AOSA 4KGHA 1BP1A 3AOTA 1USVB 3UV1A 5I7KA 2RQFA 3E8WA 3A1ZA 1EWFA 4G0SA 5I7LA 3L6IA 3ZPMA 3E8TA 4M4DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BP1 A;  4KGO A;  1EWF A;  4EWS A;  5I7K A;  4F2A A;  2OBD A;  5I7L A;  5I7J A;  3ZPM A;  4KGH A;  4M4D A; 
#chains in the Genus database with same CATH topology
 1USU B;  4F2A A;  3N72 A;  4KGO A;  3H4Z A;  4EWS A;  2OBD A;  5I7J A;  2RCK A;  3AOS A;  4KGH A;  1BP1 A;  3AOT A;  1USV B;  3UV1 A;  5I7K A;  2RQF A;  3E8W A;  3A1Z A;  1EWF A;  4G0S A;  5I7L A;  3L6I A;  3ZPM A;  3E8T A;  4M4D A; 
#chains in the Genus database with same CATH homology
 1USU B;  4F2A A;  3N72 A;  4KGO A;  3H4Z A;  4EWS A;  2OBD A;  5I7J A;  2RCK A;  3AOS A;  4KGH A;  1BP1 A;  3AOT A;  1USV B;  3UV1 A;  5I7K A;  2RQF A;  3E8W A;  3A1Z A;  1EWF A;  4G0S A;  5I7L A;  3L6I A;  3ZPM A;  3E8T A;  4M4D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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