4KGOA

Crystal structure of double leucine to methionine mutant human splunc1 lacking the secretion signal sequence
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
212
structure length
183
Chain Sequence
SPTGLAGSLTNALSNGLLSGGLLGIMENLPLLDIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKMDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLDGLGPLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords BPI fold-containing family A member 1
total genus 38
structure length 183
sequence length 212
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 4kgoA00
4EWSA 4KGOA 1BP1A 5I7JA 4M4DA 3ZPMA 5I7KA 1EWFA 5I7LA 4F2AA 4KGHA 2OBDA
chains in the Genus database with same CATH superfamily
4EWSA 1BP1A 5I7JA 4F2AA 3AOTA 3A1ZA 5I7LA 3AOSA 4KGOA 3E8TA 3ZPMA 3UV1A 1EWFA 3N72A 2RQFA 2RCKA 4G0SA 4M4DA 1USVB 3L6IA 3H4ZA 1USUB 5I7KA 4KGHA 3E8WA 2OBDA
chains in the Genus database with same CATH topology
4EWSA 1BP1A 5I7JA 4F2AA 3AOTA 3A1ZA 5I7LA 3AOSA 4KGOA 3E8TA 3ZPMA 3UV1A 1EWFA 3N72A 2RQFA 2RCKA 4G0SA 4M4DA 1USVB 3L6IA 3H4ZA 1USUB 5I7KA 4KGHA 3E8WA 2OBDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EWS A;  4KGO A;  1BP1 A;  5I7J A;  4M4D A;  3ZPM A;  5I7K A;  1EWF A;  5I7L A;  4F2A A;  4KGH A;  2OBD A; 
#chains in the Genus database with same CATH topology
 4EWS A;  1BP1 A;  5I7J A;  4F2A A;  3AOT A;  3A1Z A;  5I7L A;  3AOS A;  4KGO A;  3E8T A;  3ZPM A;  3UV1 A;  1EWF A;  3N72 A;  2RQF A;  2RCK A;  4G0S A;  4M4D A;  1USV B;  3L6I A;  3H4Z A;  1USU B;  5I7K A;  4KGH A;  3E8W A;  2OBD A; 
#chains in the Genus database with same CATH homology
 4EWS A;  1BP1 A;  5I7J A;  4F2A A;  3AOT A;  3A1Z A;  5I7L A;  3AOS A;  4KGO A;  3E8T A;  3ZPM A;  3UV1 A;  1EWF A;  3N72 A;  2RQF A;  2RCK A;  4G0S A;  4M4D A;  1USV B;  3L6I A;  3H4Z A;  1USU B;  5I7K A;  4KGH A;  3E8W A;  2OBD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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