4TZ7A

Crystal structure of type i phosphatidylinositol 4-phosphate 5-kinase alpha from zebrafish
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
370
structure length
303
Chain Sequence
TTSSALKGAIQLGITHSVGSLSQKPERDVLMQDFEVVESIFFPSQGSSSTPGHHHGDFKFKTYAPIAFRYFREMFGIRPDDYLYSLCNEPLIELSNPGSLFYVSSDDEFIIKTVQHKEAEFLQTLLPGYFMNLNQNMRTLLPKFYGLYCVQADGKNIRIVVMNNLLPRAVPMHLKFDLKGSTYKRRASPKERSKGVPTYKDLDFMQDMPEGILLENDHYTALSRTMQRDCRVLQSFKIMDYSLLVGIHILMGGIPAFNSKGERLLVFIGIIDILQSYRTVSVHRPSFYADRFQKFMCSTVFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled.
pubmed doi rcsb
molecule tags Transferase
source organism Danio rerio
molecule keywords Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
total genus 81
structure length 303
sequence length 370
ec nomenclature
pdb deposition date 2014-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01504 PIP5K Phosphatidylinositol-4-phosphate 5-Kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.800.10 Alpha Beta 2-Layer Sandwich Phosphatidylinositol Phosphate Kinase II Beta Phosphatidylinositol Phosphate Kinase II Beta 4tz7A01
3.30.810.10 Alpha Beta 2-Layer Sandwich Phosphatidylinositol Phosphate Kinase Iibeta; Chain: A, domain 2 2-Layer Sandwich 4tz7A02
3X01A 4TZ7A 3X02A 5E3UA 3X08A 1BO1A 3X07A 3X0CA 3X04A 3X09A 2GK9A 5E3TA 3X06A 3WZZA 3X0AA 2YBXA 3X0BA 3X03A 5E3SA 3X05A
chains in the Genus database with same CATH superfamily
3X01A 4TZ7A 3X02A 5E3UA 3X08A 1BO1A 3X07A 3X0CA 3X04A 3X09A 2GK9A 5E3TA 3X06A 3WZZA 3X0AA 2YBXA 3X0BA 3X03A 5E3SA 3X05A
chains in the Genus database with same CATH topology
3X01A 4TZ7A 3X02A 5E3UA 3X08A 1BO1A 3X07A 3X0CA 3X04A 3X09A 2GK9A 5E3TA 3X06A 3WZZA 3X0AA 2YBXA 3X0BA 3X03A 5E3SA 3X05A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X01 A;  4TZ7 A;  3X02 A;  5E3U A;  3X08 A;  1BO1 A;  3X07 A;  3X0C A;  3X04 A;  3X09 A;  2GK9 A;  5E3T A;  3X06 A;  3WZZ A;  3X0A A;  2YBX A;  3X0B A;  3X03 A;  5E3S A;  3X05 A; 
#chains in the Genus database with same CATH topology
 3X01 A;  4TZ7 A;  3X02 A;  5E3U A;  3X08 A;  1BO1 A;  3X07 A;  3X0C A;  3X04 A;  3X09 A;  2GK9 A;  5E3T A;  3X06 A;  3WZZ A;  3X0A A;  2YBX A;  3X0B A;  3X03 A;  5E3S A;  3X05 A; 
#chains in the Genus database with same CATH homology
 3X01 A;  4TZ7 A;  3X02 A;  5E3U A;  3X08 A;  1BO1 A;  3X07 A;  3X0C A;  3X04 A;  3X09 A;  2GK9 A;  5E3T A;  3X06 A;  3WZZ A;  3X0A A;  2YBX A;  3X0B A;  3X03 A;  5E3S A;  3X05 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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