4UEXA

Structure of human saposin a at lysosomal ph
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
81
structure length
81
Chain Sequence
GSLPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Human Saposin a at Lysosomal Ph.
pubmed doi rcsb
molecule keywords PROSAPOSIN
molecule tags Lipid binding protein
source organism Homo sapiens
total genus 30
structure length 81
sequence length 81
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03489 SapB_2 Saposin-like type B, region 2
A PF05184 SapB_1 Saposin-like type B, region 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.225.10 Mainly Alpha Orthogonal Bundle NK-Lysin Saposin-like 4uexA00
2R1QA 1L9LA 1OF9A 3BQPA 2RQYA 4V2OA 4UEXA 2JSAA 2JS9A 3S64A 3RFIA 1NKLA 3BQQA 3S63A 2DOBA 1QDMA 1N69A 2GTGA 4BITA 4DDJA 2W50A 1M12A 2LPNA 1SN6A 2W51A 2Z9AA 2R0RA 2RB3A 2KVDA 2QYPA
chains in the Genus database with same CATH superfamily
2R1QA 1L9LA 1OF9A 3BQPA 2RQYA 4V2OA 4UEXA 2JSAA 2JS9A 3S64A 3RFIA 1NKLA 3EUJB 3CJLA 3BQQA 3S63A 2DOBA 1QDMA 1N69A 2GTGA 4BITA 4DDJA 3EUKE 2W50A 1M12A 2JQ3A 2LPNA 1SN6A 2W51A 2Z9AA 2R0RA 2RB3A 2KVDA 2QYPA
chains in the Genus database with same CATH topology
2R1QA 1L9LA 1OF9A 3BQPA 2RQYA 4V2OA 4UEXA 2JSAA 2JS9A 3S64A 3RFIA 1NKLA 3BQQA 3S63A 2DOBA 1QDMA 1N69A 2GTGA 4BITA 4DDJA 2W50A 1M12A 2LPNA 1SN6A 2W51A 2Z9AA 2R0RA 2RB3A 2KVDA 2QYPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R1Q A;  1L9L A;  1OF9 A;  3BQP A;  2RQY A;  4V2O A;  4UEX A;  2JSA A;  2JS9 A;  3S64 A;  3RFI A;  1NKL A;  3BQQ A;  3S63 A;  2DOB A;  1QDM A;  1N69 A;  2GTG A;  4BIT A;  4DDJ A;  2W50 A;  1M12 A;  2LPN A;  1SN6 A;  2W51 A;  2Z9A A;  2R0R A;  2RB3 A;  2KVD A;  2QYP A; 
#chains in the Genus database with same CATH topology
 2R1Q A;  1L9L A;  1OF9 A;  3BQP A;  2RQY A;  4V2O A;  4UEX A;  2JSA A;  2JS9 A;  3S64 A;  3RFI A;  1NKL A;  3EUJ B;  3CJL A;  3BQQ A;  3S63 A;  2DOB A;  1QDM A;  1N69 A;  2GTG A;  4BIT A;  4DDJ A;  3EUK E;  2W50 A;  1M12 A;  2JQ3 A;  2LPN A;  1SN6 A;  2W51 A;  2Z9A A;  2R0R A;  2RB3 A;  2KVD A;  2QYP A; 
#chains in the Genus database with same CATH homology
 2R1Q A;  1L9L A;  1OF9 A;  3BQP A;  2RQY A;  4V2O A;  4UEX A;  2JSA A;  2JS9 A;  3S64 A;  3RFI A;  1NKL A;  3BQQ A;  3S63 A;  2DOB A;  1QDM A;  1N69 A;  2GTG A;  4BIT A;  4DDJ A;  2W50 A;  1M12 A;  2LPN A;  1SN6 A;  2W51 A;  2Z9A A;  2R0R A;  2RB3 A;  2KVD A;  2QYP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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