4EWSA

Crystal structure of cholesteryl ester transfer protein in complex with inhibitors
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
472
structure length
472
Chain Sequence
b'TSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQDVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTADSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITASYLESHHKGHFIYKDVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVDSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESIQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CETP
publication title Crystal structures of cholesteryl ester transfer protein in complex with inhibitors.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Lipid transport/inhibitor
total genus 126
structure length 472
sequence length 472
ec nomenclature
pdb deposition date 2012-04-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
A PF02886 LBP_BPI_CETP_C LBP / BPI / CETP family, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 4ewsA02
3.15.20.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 2 Bactericidal permeability-increasing protein; domain 2 4ewsA01
4KGOA 4KGHA 3ZPMA 5I7LA 4M4DA 1BP1A 1EWFA 5I7KA 5I7JA 2OBDA 4EWSA 4F2AA
chains in the Genus database with same CATH superfamily
4KGHA 1BP1A 3UV1A 3AOSA 3N72A 4G0SA 3L6IA 3AOTA 2OBDA 3A1ZA 3ZPMA 5I7KA 3E8TA 5I7JA 3H4ZA 2RCKA 3E8WA 4EWSA 4F2AA 2RQFA 4KGOA 5I7LA 4M4DA 1EWFA 1USVB 1USUB
chains in the Genus database with same CATH topology
4KGHA 1BP1A 3UV1A 3AOSA 3N72A 4G0SA 3L6IA 3AOTA 2OBDA 3A1ZA 3ZPMA 5I7KA 3E8TA 5I7JA 3H4ZA 2RCKA 3E8WA 4EWSA 4F2AA 2RQFA 4KGOA 5I7LA 4M4DA 1EWFA 1USVB 1USUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KGO A;  4KGH A;  3ZPM A;  5I7L A;  4M4D A;  1BP1 A;  1EWF A;  5I7K A;  5I7J A;  2OBD A;  4EWS A;  4F2A A; 
#chains in the Genus database with same CATH topology
 4KGH A;  1BP1 A;  3UV1 A;  3AOS A;  3N72 A;  4G0S A;  3L6I A;  3AOT A;  2OBD A;  3A1Z A;  3ZPM A;  5I7K A;  3E8T A;  5I7J A;  3H4Z A;  2RCK A;  3E8W A;  4EWS A;  4F2A A;  2RQF A;  4KGO A;  5I7L A;  4M4D A;  1EWF A;  1USV B;  1USU B; 
#chains in the Genus database with same CATH homology
 4KGH A;  1BP1 A;  3UV1 A;  3AOS A;  3N72 A;  4G0S A;  3L6I A;  3AOT A;  2OBD A;  3A1Z A;  3ZPM A;  5I7K A;  3E8T A;  5I7J A;  3H4Z A;  2RCK A;  3E8W A;  4EWS A;  4F2A A;  2RQF A;  4KGO A;  5I7L A;  4M4D A;  1EWF A;  1USV B;  1USU B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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