4KGH | Genus

Total Genus 39

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	39
sequence length	212
structure length	193
Chain Sequence	SPTGLAGSLTNALSNGLLSGGLLGILENLPLLDILLGKVTSVIPGLNNVIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKLDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVI

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Immune system
source organism	Homo sapiens
publication title	Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways. pubmed doi rcsb
molecule keywords	BPI fold-containing family A member 1
total genus	39
structure length	193
sequence length	212
chains with identical sequence	B
ec nomenclature
pdb deposition date	2013-04-29

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01273	LBP_BPI_CETP	LBP / BPI / CETP family, N-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.15.10.10	Alpha Beta	Super Roll	Bactericidal permeability-increasing protein; domain 1	Bactericidal permeability-increasing protein; domain 1	4kghA00

2OBDA 4KGOA 4M4DA 4EWSA 4KGHA 4F2AA 5I7JA 1BP1A 5I7LA 5I7KA 3ZPMA 1EWFA
chains in the Genus database with same CATH superfamily

3N72A 1BP1A 3L6IA 2RCKA 4M4DA 3E8TA 3AOTA 3H4ZA 1EWFA 3E8WA 3A1ZA 4KGHA 5I7JA 4G0SA 5I7LA 3UV1A 3ZPMA 2RQFA 1USVB 1USUB 2OBDA 3AOSA 4KGOA 4EWSA 4F2AA 5I7KA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2OBD A;  4KGO A;  4M4D A;  4EWS A;  4KGH A;  4F2A A;  5I7J A;  1BP1 A;  5I7L A;  5I7K A;  3ZPM A;  1EWF A; 
#chains in the Genus database with same CATH topology
 3N72 A;  1BP1 A;  3L6I A;  2RCK A;  4M4D A;  3E8T A;  3AOT A;  3H4Z A;  1EWF A;  3E8W A;  3A1Z A;  4KGH A;  5I7J A;  4G0S A;  5I7L A;  3UV1 A;  3ZPM A;  2RQF A;  1USV B;  1USU B;  2OBD A;  3AOS A;  4KGO A;  4EWS A;  4F2A A;  5I7K A; 
#chains in the Genus database with same CATH homology
 3N72 A;  1BP1 A;  3L6I A;  2RCK A;  4M4D A;  3E8T A;  3AOT A;  3H4Z A;  1EWF A;  3E8W A;  3A1Z A;  4KGH A;  5I7J A;  4G0S A;  5I7L A;  3UV1 A;  3ZPM A;  2RQF A;  1USV B;  1USU B;  2OBD A;  3AOS A;  4KGO A;  4EWS A;  4F2A A;  5I7K A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4KGHA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations