4KGOA

Crystal structure of double leucine to methionine mutant human splunc1 lacking the secretion signal sequence
Total Genus 38
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
212
structure length
183
Chain Sequence
SPTGLAGSLTNALSNGLLSGGLLGIMENLPLLDIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKMDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLDGLGPLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
pubmed doi rcsb
molecule keywords BPI fold-containing family A member 1
molecule tags Immune system
source organism Homo sapiens
total genus 38
structure length 183
sequence length 212
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 4kgoA00
1BP1A 3ZPMA 5I7JA 4EWSA 4KGHA 5I7KA 5I7LA 4M4DA 4F2AA 4KGOA 1EWFA 2OBDA
chains in the Genus database with same CATH superfamily
2RQFA 3AOSA 3L6IA 3UV1A 5I7JA 4EWSA 5I7KA 3E8WA 4F2AA 2RCKA 1BP1A 1USUB 4M4DA 3A1ZA 3AOTA 1EWFA 2OBDA 4G0SA 3N72A 1USVB 3ZPMA 3E8TA 4KGHA 3H4ZA 5I7LA 4KGOA
chains in the Genus database with same CATH topology
2RQFA 3AOSA 3L6IA 3UV1A 5I7JA 4EWSA 5I7KA 3E8WA 4F2AA 2RCKA 1BP1A 1USUB 4M4DA 3A1ZA 3AOTA 1EWFA 2OBDA 4G0SA 3N72A 1USVB 3ZPMA 3E8TA 4KGHA 3H4ZA 5I7LA 4KGOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BP1 A;  3ZPM A;  5I7J A;  4EWS A;  4KGH A;  5I7K A;  5I7L A;  4M4D A;  4F2A A;  4KGO A;  1EWF A;  2OBD A; 
#chains in the Genus database with same CATH topology
 2RQF A;  3AOS A;  3L6I A;  3UV1 A;  5I7J A;  4EWS A;  5I7K A;  3E8W A;  4F2A A;  2RCK A;  1BP1 A;  1USU B;  4M4D A;  3A1Z A;  3AOT A;  1EWF A;  2OBD A;  4G0S A;  3N72 A;  1USV B;  3ZPM A;  3E8T A;  4KGH A;  3H4Z A;  5I7L A;  4KGO A; 
#chains in the Genus database with same CATH homology
 2RQF A;  3AOS A;  3L6I A;  3UV1 A;  5I7J A;  4EWS A;  5I7K A;  3E8W A;  4F2A A;  2RCK A;  1BP1 A;  1USU B;  4M4D A;  3A1Z A;  3AOT A;  1EWF A;  2OBD A;  4G0S A;  3N72 A;  1USV B;  3ZPM A;  3E8T A;  4KGH A;  3H4Z A;  5I7L A;  4KGO A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...