4KGOA

Crystal structure of double leucine to methionine mutant human splunc1 lacking the secretion signal sequence
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
212
structure length
183
Chain Sequence
b'SPTGLAGSLTNALSNGLLSGGLLGIMENLPLLDIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKMDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLDGLGPLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVI'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords BPI fold-containing family A member 1
publication title Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Immune system
total genus 38
structure length 183
sequence length 212
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 4kgoA00
5I7LA 5I7JA 1EWFA 4M4DA 4KGHA 1BP1A 3ZPMA 2OBDA 4F2AA 5I7KA 4KGOA 4EWSA
chains in the Genus database with same CATH superfamily
2RQFA 1EWFA 3UV1A 4KGHA 5I7LA 3N72A 5I7JA 3E8WA 2OBDA 4F2AA 2RCKA 3AOSA 4G0SA 3A1ZA 4M4DA 1USUB 1BP1A 3ZPMA 3L6IA 4KGOA 4EWSA 3H4ZA 3E8TA 3AOTA 5I7KA 1USVB
chains in the Genus database with same CATH topology
2RQFA 1EWFA 3UV1A 4KGHA 5I7LA 3N72A 5I7JA 3E8WA 2OBDA 4F2AA 2RCKA 3AOSA 4G0SA 3A1ZA 4M4DA 1USUB 1BP1A 3ZPMA 3L6IA 4KGOA 4EWSA 3H4ZA 3E8TA 3AOTA 5I7KA 1USVB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I7L A;  5I7J A;  1EWF A;  4M4D A;  4KGH A;  1BP1 A;  3ZPM A;  2OBD A;  4F2A A;  5I7K A;  4KGO A;  4EWS A; 
#chains in the Genus database with same CATH topology
 2RQF A;  1EWF A;  3UV1 A;  4KGH A;  5I7L A;  3N72 A;  5I7J A;  3E8W A;  2OBD A;  4F2A A;  2RCK A;  3AOS A;  4G0S A;  3A1Z A;  4M4D A;  1USU B;  1BP1 A;  3ZPM A;  3L6I A;  4KGO A;  4EWS A;  3H4Z A;  3E8T A;  3AOT A;  5I7K A;  1USV B; 
#chains in the Genus database with same CATH homology
 2RQF A;  1EWF A;  3UV1 A;  4KGH A;  5I7L A;  3N72 A;  5I7J A;  3E8W A;  2OBD A;  4F2A A;  2RCK A;  3AOS A;  4G0S A;  3A1Z A;  4M4D A;  1USU B;  1BP1 A;  3ZPM A;  3L6I A;  4KGO A;  4EWS A;  3H4Z A;  3E8T A;  3AOT A;  5I7K A;  1USV B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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