5I7KA

Crystal structure of human splunc1 dolphin mutant d1 (g58a, s61a, g62e, g63d, g66d, i67t)
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
213
structure length
199
Chain Sequence
SPTGLAGSLTNALSNALLAEDLLDTLENLPLLDILLGGLLGKVTSVIPGLNNIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKLDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLPLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1.
pubmed doi rcsb
molecule keywords BPI fold-containing family A member 1
molecule tags Antimicrobial protein
source organism Homo sapiens
total genus 46
structure length 199
sequence length 213
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 5i7kA00
5I7LA 4F2AA 4KGHA 5I7KA 4KGOA 5I7JA 1EWFA 3ZPMA 4M4DA 4EWSA 1BP1A 2OBDA
chains in the Genus database with same CATH superfamily
3E8WA 4KGHA 3E8TA 4KGOA 5I7JA 2RQFA 3ZPMA 2RCKA 1EWFA 3UV1A 1USUB 2OBDA 4F2AA 4M4DA 3A1ZA 4EWSA 1BP1A 3H4ZA 3N72A 5I7LA 1USVB 4G0SA 3AOSA 5I7KA 3AOTA 3L6IA
chains in the Genus database with same CATH topology
3E8WA 4KGHA 3E8TA 4KGOA 5I7JA 2RQFA 3ZPMA 2RCKA 1EWFA 3UV1A 1USUB 2OBDA 4F2AA 4M4DA 3A1ZA 4EWSA 1BP1A 3H4ZA 3N72A 5I7LA 1USVB 4G0SA 3AOSA 5I7KA 3AOTA 3L6IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I7L A;  4F2A A;  4KGH A;  5I7K A;  4KGO A;  5I7J A;  1EWF A;  3ZPM A;  4M4D A;  4EWS A;  1BP1 A;  2OBD A; 
#chains in the Genus database with same CATH topology
 3E8W A;  4KGH A;  3E8T A;  4KGO A;  5I7J A;  2RQF A;  3ZPM A;  2RCK A;  1EWF A;  3UV1 A;  1USU B;  2OBD A;  4F2A A;  4M4D A;  3A1Z A;  4EWS A;  1BP1 A;  3H4Z A;  3N72 A;  5I7L A;  1USV B;  4G0S A;  3AOS A;  5I7K A;  3AOT A;  3L6I A; 
#chains in the Genus database with same CATH homology
 3E8W A;  4KGH A;  3E8T A;  4KGO A;  5I7J A;  2RQF A;  3ZPM A;  2RCK A;  1EWF A;  3UV1 A;  1USU B;  2OBD A;  4F2A A;  4M4D A;  3A1Z A;  4EWS A;  1BP1 A;  3H4Z A;  3N72 A;  5I7L A;  1USV B;  4G0S A;  3AOS A;  5I7K A;  3AOT A;  3L6I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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