5I7LA

Crystal structure of splunc1 disulfide mutant m2 (a48c, v253c)
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
212
structure length
192
Chain Sequence
SPTGLCGSLTNALSNGLLSGGLLGILENLPLLDILGKVTSVIPGLNNIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVASLLRLAVKLDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLDLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFCI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1.
pubmed doi rcsb
molecule tags Antimicrobial protein
source organism Homo sapiens
molecule keywords BPI fold-containing family A member 1
total genus 45
structure length 192
sequence length 212
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 5i7lA00
5I7KA 4F2AA 2OBDA 1EWFA 4KGOA 5I7JA 4M4DA 4EWSA 5I7LA 4KGHA 1BP1A 3ZPMA
chains in the Genus database with same CATH superfamily
1USVB 3E8TA 4M4DA 3E8WA 4G0SA 4EWSA 1BP1A 3ZPMA 5I7KA 5I7JA 3H4ZA 3AOTA 2OBDA 1EWFA 3L6IA 3N72A 3AOSA 2RQFA 5I7LA 2RCKA 4KGHA 4F2AA 4KGOA 1USUB 3UV1A 3A1ZA
chains in the Genus database with same CATH topology
1USVB 3E8TA 4M4DA 3E8WA 4G0SA 4EWSA 1BP1A 3ZPMA 5I7KA 5I7JA 3H4ZA 3AOTA 2OBDA 1EWFA 3L6IA 3N72A 3AOSA 2RQFA 5I7LA 2RCKA 4KGHA 4F2AA 4KGOA 1USUB 3UV1A 3A1ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I7K A;  4F2A A;  2OBD A;  1EWF A;  4KGO A;  5I7J A;  4M4D A;  4EWS A;  5I7L A;  4KGH A;  1BP1 A;  3ZPM A; 
#chains in the Genus database with same CATH topology
 1USV B;  3E8T A;  4M4D A;  3E8W A;  4G0S A;  4EWS A;  1BP1 A;  3ZPM A;  5I7K A;  5I7J A;  3H4Z A;  3AOT A;  2OBD A;  1EWF A;  3L6I A;  3N72 A;  3AOS A;  2RQF A;  5I7L A;  2RCK A;  4KGH A;  4F2A A;  4KGO A;  1USU B;  3UV1 A;  3A1Z A; 
#chains in the Genus database with same CATH homology
 1USV B;  3E8T A;  4M4D A;  3E8W A;  4G0S A;  4EWS A;  1BP1 A;  3ZPM A;  5I7K A;  5I7J A;  3H4Z A;  3AOT A;  2OBD A;  1EWF A;  3L6I A;  3N72 A;  3AOS A;  2RQF A;  5I7L A;  2RCK A;  4KGH A;  4F2A A;  4KGO A;  1USU B;  3UV1 A;  3A1Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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