5I7KA

Crystal structure of human splunc1 dolphin mutant d1 (g58a, s61a, g62e, g63d, g66d, i67t)
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
213
structure length
199
Chain Sequence
SPTGLAGSLTNALSNALLAEDLLDTLENLPLLDILLGGLLGKVTSVIPGLNNIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKLDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLPLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1.
pubmed doi rcsb
molecule keywords BPI fold-containing family A member 1
molecule tags Antimicrobial protein
source organism Homo sapiens
total genus 46
structure length 199
sequence length 213
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 5i7kA00
3ZPMA 4F2AA 2OBDA 5I7KA 1BP1A 4KGHA 1EWFA 5I7LA 4KGOA 4M4DA 4EWSA 5I7JA
chains in the Genus database with same CATH superfamily
4F2AA 1USUB 5I7KA 1BP1A 1EWFA 4M4DA 3H4ZA 4KGHA 5I7LA 2RCKA 3A1ZA 3AOTA 3ZPMA 3E8WA 3UV1A 4G0SA 3E8TA 4EWSA 3AOSA 2RQFA 2OBDA 3L6IA 4KGOA 5I7JA 3N72A 1USVB
chains in the Genus database with same CATH topology
4F2AA 1USUB 5I7KA 1BP1A 1EWFA 4M4DA 3H4ZA 4KGHA 5I7LA 2RCKA 3A1ZA 3AOTA 3ZPMA 3E8WA 3UV1A 4G0SA 3E8TA 4EWSA 3AOSA 2RQFA 2OBDA 3L6IA 4KGOA 5I7JA 3N72A 1USVB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZPM A;  4F2A A;  2OBD A;  5I7K A;  1BP1 A;  4KGH A;  1EWF A;  5I7L A;  4KGO A;  4M4D A;  4EWS A;  5I7J A; 
#chains in the Genus database with same CATH topology
 4F2A A;  1USU B;  5I7K A;  1BP1 A;  1EWF A;  4M4D A;  3H4Z A;  4KGH A;  5I7L A;  2RCK A;  3A1Z A;  3AOT A;  3ZPM A;  3E8W A;  3UV1 A;  4G0S A;  3E8T A;  4EWS A;  3AOS A;  2RQF A;  2OBD A;  3L6I A;  4KGO A;  5I7J A;  3N72 A;  1USV B; 
#chains in the Genus database with same CATH homology
 4F2A A;  1USU B;  5I7K A;  1BP1 A;  1EWF A;  4M4D A;  3H4Z A;  4KGH A;  5I7L A;  2RCK A;  3A1Z A;  3AOT A;  3ZPM A;  3E8W A;  3UV1 A;  4G0S A;  3E8T A;  4EWS A;  3AOS A;  2RQF A;  2OBD A;  3L6I A;  4KGO A;  5I7J A;  3N72 A;  1USV B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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