5I7LA

Crystal structure of splunc1 disulfide mutant m2 (a48c, v253c)
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
212
structure length
192
Chain Sequence
SPTGLCGSLTNALSNGLLSGGLLGILENLPLLDILGKVTSVIPGLNNIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVASLLRLAVKLDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLDLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFCI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1.
pubmed doi rcsb
molecule keywords BPI fold-containing family A member 1
molecule tags Antimicrobial protein
source organism Homo sapiens
total genus 45
structure length 192
sequence length 212
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 5i7lA00
4M4DA 4EWSA 4KGOA 5I7JA 3ZPMA 4F2AA 2OBDA 5I7KA 1BP1A 4KGHA 1EWFA 5I7LA
chains in the Genus database with same CATH superfamily
4KGOA 5I7JA 3H4ZA 2OBDA 3AOTA 4F2AA 3E8WA 4G0SA 5I7KA 5I7LA 2RCKA 1USUB 4KGHA 1USVB 4M4DA 1EWFA 3N72A 3UV1A 4EWSA 3ZPMA 3A1ZA 3AOSA 1BP1A 3E8TA 2RQFA 3L6IA
chains in the Genus database with same CATH topology
4KGOA 5I7JA 3H4ZA 2OBDA 3AOTA 4F2AA 3E8WA 4G0SA 5I7KA 5I7LA 2RCKA 1USUB 4KGHA 1USVB 4M4DA 1EWFA 3N72A 3UV1A 4EWSA 3ZPMA 3A1ZA 3AOSA 1BP1A 3E8TA 2RQFA 3L6IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4M4D A;  4EWS A;  4KGO A;  5I7J A;  3ZPM A;  4F2A A;  2OBD A;  5I7K A;  1BP1 A;  4KGH A;  1EWF A;  5I7L A; 
#chains in the Genus database with same CATH topology
 4KGO A;  5I7J A;  3H4Z A;  2OBD A;  3AOT A;  4F2A A;  3E8W A;  4G0S A;  5I7K A;  5I7L A;  2RCK A;  1USU B;  4KGH A;  1USV B;  4M4D A;  1EWF A;  3N72 A;  3UV1 A;  4EWS A;  3ZPM A;  3A1Z A;  3AOS A;  1BP1 A;  3E8T A;  2RQF A;  3L6I A; 
#chains in the Genus database with same CATH homology
 4KGO A;  5I7J A;  3H4Z A;  2OBD A;  3AOT A;  4F2A A;  3E8W A;  4G0S A;  5I7K A;  5I7L A;  2RCK A;  1USU B;  4KGH A;  1USV B;  4M4D A;  1EWF A;  3N72 A;  3UV1 A;  4EWS A;  3ZPM A;  3A1Z A;  3AOS A;  1BP1 A;  3E8T A;  2RQF A;  3L6I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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