1V2XA

Trmh
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
Knots found
sequence length
191
structure length
191
Chain Sequence
MRERTEARRRRIEEVLRRRQPDLTVLLENVHKPHNLSAILRTCDAVGVLEAHAVNPTGGVPTFNETSGGSHKWVYLRVHPDLHEAFRFLKERGFTVYATALREDARDFREVDYTKPTAVLFGAEKWGVSEEALALADGAIKIPMLGMVQSLNVSVAAAVILFEAQRQRLKAGLYDRPRLDPELYQKVLADW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Deep Knot Structure for Construction of Active Site and Cofactor Binding Site of tRNA Modification Enzyme
pubmed doi rcsb
molecule tags Transferase
source organism Thermus thermophilus
molecule keywords tRNA (Gm18) methyltransferase
total genus 61
structure length 191
sequence length 191
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.34: tRNA (guanosine(18)-2'-O)-methyltransferase.
pdb deposition date 2003-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
A PF12105 SpoU_methylas_C SpoU, rRNA methylase, C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 1v2xA00
1VHYA 4YVHA 4YQDA 4MCBA 1OY5A 5GMCA 4YQNA 2CX8A 4YQLA 4YQQA 4YVIA 4MCCA 2O3AA 1MXIA 4YQ0A 3NK7A 3ILKA 4YQ3A 4YQ7A 4YQIA 4YQSA 4RG1A 4FAKA 2V3JA 1UALA 4YQ6A 4CNDA 3KY7A 4YQ4A 4YVJA 4YQCA 4X3LA 2QWVA 1VHKA 4IG6A 4JAKA 4KGNA 4YQJA 4CNGA 3KNUA 1Z85A 4YQTA 4E8BA 4YQ1A 2V3KA 1X7OA 4YVKA 3KTYA 1VH0A 4YQKA 1V6ZA 1J85A 3N4JA 4YQGA 4XBOA 4JALA 1GZ0A 4YQPA 4CNFA 3N4KA 4MCDA 3L8UA 2I6DA 3IC6A 4YQ9A 3QUVA 4KDZA 1UAKA 4CNEA 3OIJA 2EGVA 2Z0YA 3E5YA 4X3MA 2YY8A 4YPWA 5FAIA 3OINA 1X7PA 4YQAA 4H3ZA 4YQ8A 5GM8A 4YQ5A 1V2XA 2HA8A 3BBDA 4YQOA 4YQBA 1ZJRA 5D9FA 1K3RA 5GMBA 1O6DA 4YQRA 4YQ2A 3BBHA 3ONPA 3KW2A 1P9PA 3BBEA 3IEFA 1NXZA 3AXZA 4YVGA 4YPZA 1UAJA 3AI9X 3OIIA 3AIAA 5CO4A 1UAMA 4YPYA 4H3YA 3O7BA 4J3CA 4L69A 4PZKA 2EGWA 1TO0A 3NK6A 1IPAA 1NS5A 2QMMA 3DCMX 3GYQA 4YPXA
chains in the Genus database with same CATH superfamily
1VHYA 4YVHA 4YQDA 4MCBA 1OY5A 5GMCA 4YQNA 2CX8A 4YQLA 4YQQA 4YVIA 4MCCA 2O3AA 1MXIA 4YQ0A 3NK7A 3ILKA 4YQ3A 4YQ7A 4YQIA 4YQSA 4RG1A 4FAKA 2V3JA 1UALA 4YQ6A 4CNDA 3KY7A 4YQ4A 4YVJA 4YQCA 4X3LA 2QWVA 1VHKA 4IG6A 4JWGA 4JAKA 4KGNA 4YQJA 4CNGA 4JWFA 3KNUA 4FMWA 1Z85A 4YQTA 4E8BA 4YQ1A 2V3KA 1X7OA 4YVKA 3KTYA 1VH0A 4YQKA 1V6ZA 1J85A 3N4JA 4YQGA 4XBOA 4JALA 1GZ0A 4YQPA 4CNFA 3N4KA 4MCDA 3L8UA 4JWHA 2I6DA 3IC6A 4YQ9A 3QUVA 4KDZA 1UAKA 4CNEA 3OIJA 2EGVA 2Z0YA 3E5YA 4X3MA 2YY8A 4YPWA 5FAIA 3OINA 1X7PA 4YQAA 4H3ZA 4YQ8A 5GM8A 4YQ5A 1V2XA 2HA8A 3BBDA 4YQOA 4YQBA 1ZJRA 5D9FA 1K3RA 5GMBA 1O6DA 4YQRA 4YQ2A 3BBHA 3ONPA 3KW2A 1P9PA 3BBEA 3IEFA 1NXZA 3AXZA 4YVGA 4YPZA 1UAJA 3AI9X 3OIIA 4JWJA 3AIAA 5CO4A 1UAMA 4YPYA 4H3YA 3O7BA 4J3CA 4L69A 4PZKA 2EGWA 1TO0A 3NK6A 1IPAA 1NS5A 2QMMA 3DCMX 3GYQA 4YPXA
chains in the Genus database with same CATH topology
1VHYA 4YVHA 4YQDA 4MCBA 1OY5A 5GMCA 4YQNA 2CX8A 4YQLA 4YQQA 4YVIA 4MCCA 2O3AA 1MXIA 4YQ0A 3NK7A 3ILKA 4YQ3A 4YQ7A 4YQIA 4YQSA 4RG1A 4FAKA 2V3JA 1UALA 4YQ6A 4CNDA 3KY7A 4YQ4A 4YVJA 4YQCA 4X3LA 2QWVA 1VHKA 4IG6A 4JWGA 4JAKA 4KGNA 4YQJA 4CNGA 4JWFA 3KNUA 4FMWA 1Z85A 4YQTA 4E8BA 4YQ1A 2V3KA 1X7OA 4YVKA 3KTYA 1VH0A 4YQKA 1V6ZA 1J85A 3N4JA 4YQGA 4XBOA 4JALA 1GZ0A 4YQPA 4CNFA 3N4KA 4MCDA 3L8UA 4JWHA 2I6DA 3IC6A 4YQ9A 3QUVA 4KDZA 1UAKA 4CNEA 3OIJA 2EGVA 2Z0YA 3E5YA 4X3MA 2YY8A 4YPWA 5FAIA 3OINA 1X7PA 4YQAA 4H3ZA 4YQ8A 5GM8A 4YQ5A 1V2XA 2HA8A 3BBDA 4YQOA 4YQBA 1ZJRA 5D9FA 1K3RA 5GMBA 1O6DA 4YQRA 4YQ2A 3BBHA 3ONPA 3KW2A 1P9PA 3BBEA 3IEFA 1NXZA 3AXZA 4YVGA 4YPZA 1UAJA 3AI9X 3OIIA 4JWJA 3AIAA 5CO4A 1UAMA 4YPYA 4H3YA 3O7BA 4J3CA 4L69A 4PZKA 2EGWA 1TO0A 3NK6A 1IPAA 1NS5A 2QMMA 3DCMX 3GYQA 4YPXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VHY A;  4YVH A;  4YQD A;  4MCB A;  1OY5 A;  5GMC A;  4YQN A;  2CX8 A;  4YQL A;  4YQQ A;  4YVI A;  4MCC A;  2O3A A;  1MXI A;  4YQ0 A;  3NK7 A;  3ILK A;  4YQ3 A;  4YQ7 A;  4YQI A;  4YQS A;  4RG1 A;  4FAK A;  2V3J A;  1UAL A;  4YQ6 A;  4CND A;  3KY7 A;  4YQ4 A;  4YVJ A;  4YQC A;  4X3L A;  2QWV A;  1VHK A;  4IG6 A;  4JAK A;  4KGN A;  4YQJ A;  4CNG A;  3KNU A;  1Z85 A;  4YQT A;  4E8B A;  4YQ1 A;  2V3K A;  1X7O A;  4YVK A;  3KTY A;  1VH0 A;  4YQK A;  1V6Z A;  1J85 A;  3N4J A;  4YQG A;  4XBO A;  4JAL A;  1GZ0 A;  4YQP A;  4CNF A;  3N4K A;  4MCD A;  3L8U A;  2I6D A;  3IC6 A;  4YQ9 A;  3QUV A;  4KDZ A;  1UAK A;  4CNE A;  3OIJ A;  2EGV A;  2Z0Y A;  3E5Y A;  4X3M A;  2YY8 A;  4YPW A;  5FAI A;  3OIN A;  1X7P A;  4YQA A;  4H3Z A;  4YQ8 A;  5GM8 A;  4YQ5 A;  1V2X A;  2HA8 A;  3BBD A;  4YQO A;  4YQB A;  1ZJR A;  5D9F A;  1K3R A;  5GMB A;  1O6D A;  4YQR A;  4YQ2 A;  3BBH A;  3ONP A;  3KW2 A;  1P9P A;  3BBE A;  3IEF A;  1NXZ A;  3AXZ A;  4YVG A;  4YPZ A;  1UAJ A;  3AI9 X;  3OII A;  3AIA A;  5CO4 A;  1UAM A;  4YPY A;  4H3Y A;  3O7B A;  4J3C A;  4L69 A;  4PZK A;  2EGW A;  1TO0 A;  3NK6 A;  1IPA A;  1NS5 A;  2QMM A;  3DCM X;  3GYQ A;  4YPX A; 
#chains in the Genus database with same CATH topology
 1VHY A;  4YVH A;  4YQD A;  4MCB A;  1OY5 A;  5GMC A;  4YQN A;  2CX8 A;  4YQL A;  4YQQ A;  4YVI A;  4MCC A;  2O3A A;  1MXI A;  4YQ0 A;  3NK7 A;  3ILK A;  4YQ3 A;  4YQ7 A;  4YQI A;  4YQS A;  4RG1 A;  4FAK A;  2V3J A;  1UAL A;  4YQ6 A;  4CND A;  3KY7 A;  4YQ4 A;  4YVJ A;  4YQC A;  4X3L A;  2QWV A;  1VHK A;  4IG6 A;  4JWG A;  4JAK A;  4KGN A;  4YQJ A;  4CNG A;  4JWF A;  3KNU A;  4FMW A;  1Z85 A;  4YQT A;  4E8B A;  4YQ1 A;  2V3K A;  1X7O A;  4YVK A;  3KTY A;  1VH0 A;  4YQK A;  1V6Z A;  1J85 A;  3N4J A;  4YQG A;  4XBO A;  4JAL A;  1GZ0 A;  4YQP A;  4CNF A;  3N4K A;  4MCD A;  3L8U A;  4JWH A;  2I6D A;  3IC6 A;  4YQ9 A;  3QUV A;  4KDZ A;  1UAK A;  4CNE A;  3OIJ A;  2EGV A;  2Z0Y A;  3E5Y A;  4X3M A;  2YY8 A;  4YPW A;  5FAI A;  3OIN A;  1X7P A;  4YQA A;  4H3Z A;  4YQ8 A;  5GM8 A;  4YQ5 A;  1V2X A;  2HA8 A;  3BBD A;  4YQO A;  4YQB A;  1ZJR A;  5D9F A;  1K3R A;  5GMB A;  1O6D A;  4YQR A;  4YQ2 A;  3BBH A;  3ONP A;  3KW2 A;  1P9P A;  3BBE A;  3IEF A;  1NXZ A;  3AXZ A;  4YVG A;  4YPZ A;  1UAJ A;  3AI9 X;  3OII A;  4JWJ A;  3AIA A;  5CO4 A;  1UAM A;  4YPY A;  4H3Y A;  3O7B A;  4J3C A;  4L69 A;  4PZK A;  2EGW A;  1TO0 A;  3NK6 A;  1IPA A;  1NS5 A;  2QMM A;  3DCM X;  3GYQ A;  4YPX A; 
#chains in the Genus database with same CATH homology
 1VHY A;  4YVH A;  4YQD A;  4MCB A;  1OY5 A;  5GMC A;  4YQN A;  2CX8 A;  4YQL A;  4YQQ A;  4YVI A;  4MCC A;  2O3A A;  1MXI A;  4YQ0 A;  3NK7 A;  3ILK A;  4YQ3 A;  4YQ7 A;  4YQI A;  4YQS A;  4RG1 A;  4FAK A;  2V3J A;  1UAL A;  4YQ6 A;  4CND A;  3KY7 A;  4YQ4 A;  4YVJ A;  4YQC A;  4X3L A;  2QWV A;  1VHK A;  4IG6 A;  4JWG A;  4JAK A;  4KGN A;  4YQJ A;  4CNG A;  4JWF A;  3KNU A;  4FMW A;  1Z85 A;  4YQT A;  4E8B A;  4YQ1 A;  2V3K A;  1X7O A;  4YVK A;  3KTY A;  1VH0 A;  4YQK A;  1V6Z A;  1J85 A;  3N4J A;  4YQG A;  4XBO A;  4JAL A;  1GZ0 A;  4YQP A;  4CNF A;  3N4K A;  4MCD A;  3L8U A;  4JWH A;  2I6D A;  3IC6 A;  4YQ9 A;  3QUV A;  4KDZ A;  1UAK A;  4CNE A;  3OIJ A;  2EGV A;  2Z0Y A;  3E5Y A;  4X3M A;  2YY8 A;  4YPW A;  5FAI A;  3OIN A;  1X7P A;  4YQA A;  4H3Z A;  4YQ8 A;  5GM8 A;  4YQ5 A;  1V2X A;  2HA8 A;  3BBD A;  4YQO A;  4YQB A;  1ZJR A;  5D9F A;  1K3R A;  5GMB A;  1O6D A;  4YQR A;  4YQ2 A;  3BBH A;  3ONP A;  3KW2 A;  1P9P A;  3BBE A;  3IEF A;  1NXZ A;  3AXZ A;  4YVG A;  4YPZ A;  1UAJ A;  3AI9 X;  3OII A;  4JWJ A;  3AIA A;  5CO4 A;  1UAM A;  4YPY A;  4H3Y A;  3O7B A;  4J3C A;  4L69 A;  4PZK A;  2EGW A;  1TO0 A;  3NK6 A;  1IPA A;  1NS5 A;  2QMM A;  3DCM X;  3GYQ A;  4YPX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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