1V2XA

Trmh
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
Knots found
sequence length
191
structure length
191
Chain Sequence
MRERTEARRRRIEEVLRRRQPDLTVLLENVHKPHNLSAILRTCDAVGVLEAHAVNPTGGVPTFNETSGGSHKWVYLRVHPDLHEAFRFLKERGFTVYATALREDARDFREVDYTKPTAVLFGAEKWGVSEEALALADGAIKIPMLGMVQSLNVSVAAAVILFEAQRQRLKAGLYDRPRLDPELYQKVLADW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Deep Knot Structure for Construction of Active Site and Cofactor Binding Site of tRNA Modification Enzyme
pubmed doi rcsb
molecule tags Transferase
source organism Thermus thermophilus
molecule keywords tRNA (Gm18) methyltransferase
total genus 61
structure length 191
sequence length 191
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.34: tRNA (guanosine(18)-2'-O)-methyltransferase.
pdb deposition date 2003-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
A PF12105 SpoU_methylas_C SpoU, rRNA methylase, C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 1v2xA00
1NXZA 4CNGA 4YVIA 3OIJA 2QWVA 4MCDA 1IPAA 1GZ0A 4J3CA 3BBDA 4H3ZA 4JALA 4YQDA 2EGWA 1ZJRA 2CX8A 3IEFA 5D9FA 1K3RA 4YQOA 4YQKA 2O3AA 4YQ6A 3N4KA 4YQGA 4MCBA 3BBHA 1MXIA 2V3JA 4YVHA 4YQLA 3IC6A 3KW2A 2I6DA 4YQ4A 4MCCA 4KDZA 4YQIA 3DCMX 4YVKA 4YQ0A 5FAIA 2V3KA 4YQ3A 4YQ1A 3KTYA 1Z85A 4YPWA 1J85A 1P9PA 4YQ5A 2QMMA 4X3MA 3O7BA 4YPXA 1UALA 3GYQA 1NS5A 1V6ZA 3AI9X 4CNEA 1O6DA 4KGNA 1UAKA 1X7OA 3AXZA 3KY7A 4YQRA 4RG1A 4PZKA 3E5YA 4YQ2A 4YQ7A 5GMBA 4YQPA 4FAKA 3OINA 4YQBA 3AIAA 5CO4A 1VHYA 3OIIA 4YQ8A 4YQSA 1OY5A 1UAJA 4H3YA 1VH0A 1TO0A 4YVGA 4YQJA 3ILKA 4YQAA 2HA8A 3QUVA 4CNFA 3KNUA 4IG6A 1VHKA 4YPZA 1UAMA 5GM8A 4YQTA 1X7PA 2Z0YA 4X3LA 4E8BA 3BBEA 3NK6A 1V2XA 3N4JA 4YQCA 5GMCA 4YVJA 4XBOA 4YQQA 4L69A 2EGVA 4YPYA 3L8UA 3NK7A 4JAKA 4YQNA 3ONPA 4YQ9A 2YY8A 4CNDA
chains in the Genus database with same CATH superfamily
1NXZA 4CNGA 4YVIA 3OIJA 2QWVA 4MCDA 1IPAA 1GZ0A 4J3CA 3BBDA 4H3ZA 4JALA 4FMWA 4YQDA 2EGWA 1ZJRA 2CX8A 3IEFA 5D9FA 1K3RA 4YQOA 4YQKA 2O3AA 4YQ6A 3N4KA 4YQGA 4MCBA 3BBHA 1MXIA 2V3JA 4YVHA 4YQLA 3IC6A 3KW2A 4JWJA 2I6DA 4YQ4A 4MCCA 4KDZA 4YQIA 3DCMX 4YVKA 4YQ0A 5FAIA 2V3KA 4YQ3A 4YQ1A 3KTYA 1Z85A 4YPWA 1J85A 1P9PA 4YQ5A 2QMMA 4X3MA 3O7BA 4YPXA 1UALA 3GYQA 1NS5A 1V6ZA 4JWGA 3AI9X 4CNEA 1O6DA 4KGNA 1UAKA 1X7OA 3AXZA 3KY7A 4YQRA 4RG1A 4PZKA 3E5YA 4YQ2A 4YQ7A 5GMBA 4YQPA 4FAKA 3OINA 4YQBA 3AIAA 5CO4A 1VHYA 3OIIA 4YQ8A 4YQSA 1OY5A 1UAJA 4H3YA 1VH0A 4JWFA 1TO0A 4YVGA 4YQJA 3ILKA 4YQAA 2HA8A 3QUVA 4CNFA 4JWHA 3KNUA 4IG6A 1VHKA 4YPZA 1UAMA 5GM8A 4YQTA 1X7PA 2Z0YA 4X3LA 4E8BA 3BBEA 3NK6A 1V2XA 3N4JA 4YQCA 5GMCA 4YVJA 4XBOA 4YQQA 4L69A 2EGVA 4YPYA 3L8UA 3NK7A 4JAKA 4YQNA 3ONPA 4YQ9A 2YY8A 4CNDA
chains in the Genus database with same CATH topology
1NXZA 4CNGA 4YVIA 3OIJA 2QWVA 4MCDA 1IPAA 1GZ0A 4J3CA 3BBDA 4H3ZA 4JALA 4FMWA 4YQDA 2EGWA 1ZJRA 2CX8A 3IEFA 5D9FA 1K3RA 4YQOA 4YQKA 2O3AA 4YQ6A 3N4KA 4YQGA 4MCBA 3BBHA 1MXIA 2V3JA 4YVHA 4YQLA 3IC6A 3KW2A 4JWJA 2I6DA 4YQ4A 4MCCA 4KDZA 4YQIA 3DCMX 4YVKA 4YQ0A 5FAIA 2V3KA 4YQ3A 4YQ1A 3KTYA 1Z85A 4YPWA 1J85A 1P9PA 4YQ5A 2QMMA 4X3MA 3O7BA 4YPXA 1UALA 3GYQA 1NS5A 1V6ZA 4JWGA 3AI9X 4CNEA 1O6DA 4KGNA 1UAKA 1X7OA 3AXZA 3KY7A 4YQRA 4RG1A 4PZKA 3E5YA 4YQ2A 4YQ7A 5GMBA 4YQPA 4FAKA 3OINA 4YQBA 3AIAA 5CO4A 1VHYA 3OIIA 4YQ8A 4YQSA 1OY5A 1UAJA 4H3YA 1VH0A 4JWFA 1TO0A 4YVGA 4YQJA 3ILKA 4YQAA 2HA8A 3QUVA 4CNFA 4JWHA 3KNUA 4IG6A 1VHKA 4YPZA 1UAMA 5GM8A 4YQTA 1X7PA 2Z0YA 4X3LA 4E8BA 3BBEA 3NK6A 1V2XA 3N4JA 4YQCA 5GMCA 4YVJA 4XBOA 4YQQA 4L69A 2EGVA 4YPYA 3L8UA 3NK7A 4JAKA 4YQNA 3ONPA 4YQ9A 2YY8A 4CNDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NXZ A;  4CNG A;  4YVI A;  3OIJ A;  2QWV A;  4MCD A;  1IPA A;  1GZ0 A;  4J3C A;  3BBD A;  4H3Z A;  4JAL A;  4YQD A;  2EGW A;  1ZJR A;  2CX8 A;  3IEF A;  5D9F A;  1K3R A;  4YQO A;  4YQK A;  2O3A A;  4YQ6 A;  3N4K A;  4YQG A;  4MCB A;  3BBH A;  1MXI A;  2V3J A;  4YVH A;  4YQL A;  3IC6 A;  3KW2 A;  2I6D A;  4YQ4 A;  4MCC A;  4KDZ A;  4YQI A;  3DCM X;  4YVK A;  4YQ0 A;  5FAI A;  2V3K A;  4YQ3 A;  4YQ1 A;  3KTY A;  1Z85 A;  4YPW A;  1J85 A;  1P9P A;  4YQ5 A;  2QMM A;  4X3M A;  3O7B A;  4YPX A;  1UAL A;  3GYQ A;  1NS5 A;  1V6Z A;  3AI9 X;  4CNE A;  1O6D A;  4KGN A;  1UAK A;  1X7O A;  3AXZ A;  3KY7 A;  4YQR A;  4RG1 A;  4PZK A;  3E5Y A;  4YQ2 A;  4YQ7 A;  5GMB A;  4YQP A;  4FAK A;  3OIN A;  4YQB A;  3AIA A;  5CO4 A;  1VHY A;  3OII A;  4YQ8 A;  4YQS A;  1OY5 A;  1UAJ A;  4H3Y A;  1VH0 A;  1TO0 A;  4YVG A;  4YQJ A;  3ILK A;  4YQA A;  2HA8 A;  3QUV A;  4CNF A;  3KNU A;  4IG6 A;  1VHK A;  4YPZ A;  1UAM A;  5GM8 A;  4YQT A;  1X7P A;  2Z0Y A;  4X3L A;  4E8B A;  3BBE A;  3NK6 A;  1V2X A;  3N4J A;  4YQC A;  5GMC A;  4YVJ A;  4XBO A;  4YQQ A;  4L69 A;  2EGV A;  4YPY A;  3L8U A;  3NK7 A;  4JAK A;  4YQN A;  3ONP A;  4YQ9 A;  2YY8 A;  4CND A; 
#chains in the Genus database with same CATH topology
 1NXZ A;  4CNG A;  4YVI A;  3OIJ A;  2QWV A;  4MCD A;  1IPA A;  1GZ0 A;  4J3C A;  3BBD A;  4H3Z A;  4JAL A;  4FMW A;  4YQD A;  2EGW A;  1ZJR A;  2CX8 A;  3IEF A;  5D9F A;  1K3R A;  4YQO A;  4YQK A;  2O3A A;  4YQ6 A;  3N4K A;  4YQG A;  4MCB A;  3BBH A;  1MXI A;  2V3J A;  4YVH A;  4YQL A;  3IC6 A;  3KW2 A;  4JWJ A;  2I6D A;  4YQ4 A;  4MCC A;  4KDZ A;  4YQI A;  3DCM X;  4YVK A;  4YQ0 A;  5FAI A;  2V3K A;  4YQ3 A;  4YQ1 A;  3KTY A;  1Z85 A;  4YPW A;  1J85 A;  1P9P A;  4YQ5 A;  2QMM A;  4X3M A;  3O7B A;  4YPX A;  1UAL A;  3GYQ A;  1NS5 A;  1V6Z A;  4JWG A;  3AI9 X;  4CNE A;  1O6D A;  4KGN A;  1UAK A;  1X7O A;  3AXZ A;  3KY7 A;  4YQR A;  4RG1 A;  4PZK A;  3E5Y A;  4YQ2 A;  4YQ7 A;  5GMB A;  4YQP A;  4FAK A;  3OIN A;  4YQB A;  3AIA A;  5CO4 A;  1VHY A;  3OII A;  4YQ8 A;  4YQS A;  1OY5 A;  1UAJ A;  4H3Y A;  1VH0 A;  4JWF A;  1TO0 A;  4YVG A;  4YQJ A;  3ILK A;  4YQA A;  2HA8 A;  3QUV A;  4CNF A;  4JWH A;  3KNU A;  4IG6 A;  1VHK A;  4YPZ A;  1UAM A;  5GM8 A;  4YQT A;  1X7P A;  2Z0Y A;  4X3L A;  4E8B A;  3BBE A;  3NK6 A;  1V2X A;  3N4J A;  4YQC A;  5GMC A;  4YVJ A;  4XBO A;  4YQQ A;  4L69 A;  2EGV A;  4YPY A;  3L8U A;  3NK7 A;  4JAK A;  4YQN A;  3ONP A;  4YQ9 A;  2YY8 A;  4CND A; 
#chains in the Genus database with same CATH homology
 1NXZ A;  4CNG A;  4YVI A;  3OIJ A;  2QWV A;  4MCD A;  1IPA A;  1GZ0 A;  4J3C A;  3BBD A;  4H3Z A;  4JAL A;  4FMW A;  4YQD A;  2EGW A;  1ZJR A;  2CX8 A;  3IEF A;  5D9F A;  1K3R A;  4YQO A;  4YQK A;  2O3A A;  4YQ6 A;  3N4K A;  4YQG A;  4MCB A;  3BBH A;  1MXI A;  2V3J A;  4YVH A;  4YQL A;  3IC6 A;  3KW2 A;  4JWJ A;  2I6D A;  4YQ4 A;  4MCC A;  4KDZ A;  4YQI A;  3DCM X;  4YVK A;  4YQ0 A;  5FAI A;  2V3K A;  4YQ3 A;  4YQ1 A;  3KTY A;  1Z85 A;  4YPW A;  1J85 A;  1P9P A;  4YQ5 A;  2QMM A;  4X3M A;  3O7B A;  4YPX A;  1UAL A;  3GYQ A;  1NS5 A;  1V6Z A;  4JWG A;  3AI9 X;  4CNE A;  1O6D A;  4KGN A;  1UAK A;  1X7O A;  3AXZ A;  3KY7 A;  4YQR A;  4RG1 A;  4PZK A;  3E5Y A;  4YQ2 A;  4YQ7 A;  5GMB A;  4YQP A;  4FAK A;  3OIN A;  4YQB A;  3AIA A;  5CO4 A;  1VHY A;  3OII A;  4YQ8 A;  4YQS A;  1OY5 A;  1UAJ A;  4H3Y A;  1VH0 A;  4JWF A;  1TO0 A;  4YVG A;  4YQJ A;  3ILK A;  4YQA A;  2HA8 A;  3QUV A;  4CNF A;  4JWH A;  3KNU A;  4IG6 A;  1VHK A;  4YPZ A;  1UAM A;  5GM8 A;  4YQT A;  1X7P A;  2Z0Y A;  4X3L A;  4E8B A;  3BBE A;  3NK6 A;  1V2X A;  3N4J A;  4YQC A;  5GMC A;  4YVJ A;  4XBO A;  4YQQ A;  4L69 A;  2EGV A;  4YPY A;  3L8U A;  3NK7 A;  4JAK A;  4YQN A;  3ONP A;  4YQ9 A;  2YY8 A;  4CND A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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