2HA8A

Methyltransferase domain of human tar (hiv-1) rna binding protein 1
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
Knots found
sequence length
159
structure length
159
Chain Sequence
LGKSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWLPLVEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQYCFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of Methyltransferase Domain of Human TAR (HIV-1) RNA binding protein 1 in complex with S-adenosyl-L-homocystein.
rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords TAR (HIV-1) RNA loop binding protein
total genus 57
structure length 159
sequence length 159
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature
pdb deposition date 2006-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2ha8A01
4YVJA 4XBOA 4YQ5A 4X3LA 3N4KA 4X3MA 3IC6A 1MXIA 4YVIA 3KNUA 3O7BA 4YQ7A 2O3AA 4H3ZA 1UAKA 4CNFA 4YQTA 5GM8A 4YQ8A 3L8UA 4YQ9A 4MCDA 3BBEA 1UAJA 4FAKA 2EGWA 4YQ1A 1V6ZA 4CNDA 1UAMA 1P9PA 1K3RA 3KTYA 4YQKA 1VHYA 3DCMX 4YQGA 4YQIA 1TO0A 3OIJA 4YPYA 4YQRA 1O6DA 5D9FA 4CNEA 1X7OA 4YQBA 3QUVA 3N4JA 4RG1A 1UALA 4YQAA 3NK6A 4YVGA 4YPXA 3NK7A 4E8BA 4YQNA 1J85A 1GZ0A 1OY5A 1X7PA 5GMBA 1NXZA 4J3CA 4YQPA 4YQDA 5CO4A 4MCCA 4YPZA 3IEFA 2CX8A 1IPAA 1VHKA 1Z85A 3BBHA 1VH0A 4JAKA 2EGVA 4YQ6A 1ZJRA 3GYQA 4YQQA 4L69A 4KGNA 4YQSA 5GMCA 1V2XA 3AI9X 2QWVA 4MCBA 4YQLA 4YVHA 2HA8A 4YQCA 3KY7A 3KW2A 4IG6A 5FAIA 1NS5A 4YQ4A 4H3YA 3BBDA 4YVKA 3OIIA 2V3JA 2Z0YA 3ONPA 2V3KA 3ILKA 4YQ0A 4CNGA 4PZKA 3OINA 3AIAA 3AXZA 2QMMA 4JALA 3E5YA 2I6DA 4YQJA 4YQ3A 4KDZA 2YY8A 4YQ2A 4YQOA 4YPWA
chains in the Genus database with same CATH superfamily
4JWJA 4YVJA 4XBOA 4YQ5A 4X3LA 3N4KA 4X3MA 3IC6A 1MXIA 4YVIA 3KNUA 3O7BA 4YQ7A 2O3AA 4H3ZA 4JWGA 1UAKA 4CNFA 4YQTA 5GM8A 4YQ8A 3L8UA 4YQ9A 4MCDA 3BBEA 1UAJA 4FMWA 4FAKA 2EGWA 4YQ1A 1V6ZA 4CNDA 1UAMA 1P9PA 1K3RA 3KTYA 4YQKA 1VHYA 3DCMX 4YQGA 4YQIA 1TO0A 3OIJA 4YPYA 4YQRA 1O6DA 5D9FA 4CNEA 1X7OA 4YQBA 4JWHA 3QUVA 3N4JA 4RG1A 1UALA 4YQAA 3NK6A 4YVGA 4YPXA 3NK7A 4E8BA 4YQNA 1J85A 1GZ0A 1OY5A 1X7PA 5GMBA 1NXZA 4J3CA 4YQPA 4YQDA 5CO4A 4MCCA 4YPZA 3IEFA 2CX8A 1IPAA 1VHKA 1Z85A 3BBHA 1VH0A 4JAKA 2EGVA 4YQ6A 1ZJRA 3GYQA 4YQQA 4L69A 4KGNA 4YQSA 5GMCA 1V2XA 3AI9X 2QWVA 4MCBA 4YQLA 4YVHA 2HA8A 4YQCA 3KY7A 3KW2A 4IG6A 5FAIA 1NS5A 4YQ4A 4H3YA 3BBDA 4YVKA 3OIIA 2V3JA 2Z0YA 3ONPA 2V3KA 3ILKA 4YQ0A 4CNGA 4PZKA 3OINA 3AIAA 3AXZA 2QMMA 4JALA 3E5YA 2I6DA 4JWFA 4YQJA 4YQ3A 4KDZA 2YY8A 4YQ2A 4YQOA 4YPWA
chains in the Genus database with same CATH topology
4JWJA 4YVJA 4XBOA 4YQ5A 4X3LA 3N4KA 4X3MA 3IC6A 1MXIA 4YVIA 3KNUA 3O7BA 4YQ7A 2O3AA 4H3ZA 4JWGA 1UAKA 4CNFA 4YQTA 5GM8A 4YQ8A 3L8UA 4YQ9A 4MCDA 3BBEA 1UAJA 4FMWA 4FAKA 2EGWA 4YQ1A 1V6ZA 4CNDA 1UAMA 1P9PA 1K3RA 3KTYA 4YQKA 1VHYA 3DCMX 4YQGA 4YQIA 1TO0A 3OIJA 4YPYA 4YQRA 1O6DA 5D9FA 4CNEA 1X7OA 4YQBA 4JWHA 3QUVA 3N4JA 4RG1A 1UALA 4YQAA 3NK6A 4YVGA 4YPXA 3NK7A 4E8BA 4YQNA 1J85A 1GZ0A 1OY5A 1X7PA 5GMBA 1NXZA 4J3CA 4YQPA 4YQDA 5CO4A 4MCCA 4YPZA 3IEFA 2CX8A 1IPAA 1VHKA 1Z85A 3BBHA 1VH0A 4JAKA 2EGVA 4YQ6A 1ZJRA 3GYQA 4YQQA 4L69A 4KGNA 4YQSA 5GMCA 1V2XA 3AI9X 2QWVA 4MCBA 4YQLA 4YVHA 2HA8A 4YQCA 3KY7A 3KW2A 4IG6A 5FAIA 1NS5A 4YQ4A 4H3YA 3BBDA 4YVKA 3OIIA 2V3JA 2Z0YA 3ONPA 2V3KA 3ILKA 4YQ0A 4CNGA 4PZKA 3OINA 3AIAA 3AXZA 2QMMA 4JALA 3E5YA 2I6DA 4JWFA 4YQJA 4YQ3A 4KDZA 2YY8A 4YQ2A 4YQOA 4YPWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YVJ A;  4XBO A;  4YQ5 A;  4X3L A;  3N4K A;  4X3M A;  3IC6 A;  1MXI A;  4YVI A;  3KNU A;  3O7B A;  4YQ7 A;  2O3A A;  4H3Z A;  1UAK A;  4CNF A;  4YQT A;  5GM8 A;  4YQ8 A;  3L8U A;  4YQ9 A;  4MCD A;  3BBE A;  1UAJ A;  4FAK A;  2EGW A;  4YQ1 A;  1V6Z A;  4CND A;  1UAM A;  1P9P A;  1K3R A;  3KTY A;  4YQK A;  1VHY A;  3DCM X;  4YQG A;  4YQI A;  1TO0 A;  3OIJ A;  4YPY A;  4YQR A;  1O6D A;  5D9F A;  4CNE A;  1X7O A;  4YQB A;  3QUV A;  3N4J A;  4RG1 A;  1UAL A;  4YQA A;  3NK6 A;  4YVG A;  4YPX A;  3NK7 A;  4E8B A;  4YQN A;  1J85 A;  1GZ0 A;  1OY5 A;  1X7P A;  5GMB A;  1NXZ A;  4J3C A;  4YQP A;  4YQD A;  5CO4 A;  4MCC A;  4YPZ A;  3IEF A;  2CX8 A;  1IPA A;  1VHK A;  1Z85 A;  3BBH A;  1VH0 A;  4JAK A;  2EGV A;  4YQ6 A;  1ZJR A;  3GYQ A;  4YQQ A;  4L69 A;  4KGN A;  4YQS A;  5GMC A;  1V2X A;  3AI9 X;  2QWV A;  4MCB A;  4YQL A;  4YVH A;  2HA8 A;  4YQC A;  3KY7 A;  3KW2 A;  4IG6 A;  5FAI A;  1NS5 A;  4YQ4 A;  4H3Y A;  3BBD A;  4YVK A;  3OII A;  2V3J A;  2Z0Y A;  3ONP A;  2V3K A;  3ILK A;  4YQ0 A;  4CNG A;  4PZK A;  3OIN A;  3AIA A;  3AXZ A;  2QMM A;  4JAL A;  3E5Y A;  2I6D A;  4YQJ A;  4YQ3 A;  4KDZ A;  2YY8 A;  4YQ2 A;  4YQO A;  4YPW A; 
#chains in the Genus database with same CATH topology
 4JWJ A;  4YVJ A;  4XBO A;  4YQ5 A;  4X3L A;  3N4K A;  4X3M A;  3IC6 A;  1MXI A;  4YVI A;  3KNU A;  3O7B A;  4YQ7 A;  2O3A A;  4H3Z A;  4JWG A;  1UAK A;  4CNF A;  4YQT A;  5GM8 A;  4YQ8 A;  3L8U A;  4YQ9 A;  4MCD A;  3BBE A;  1UAJ A;  4FMW A;  4FAK A;  2EGW A;  4YQ1 A;  1V6Z A;  4CND A;  1UAM A;  1P9P A;  1K3R A;  3KTY A;  4YQK A;  1VHY A;  3DCM X;  4YQG A;  4YQI A;  1TO0 A;  3OIJ A;  4YPY A;  4YQR A;  1O6D A;  5D9F A;  4CNE A;  1X7O A;  4YQB A;  4JWH A;  3QUV A;  3N4J A;  4RG1 A;  1UAL A;  4YQA A;  3NK6 A;  4YVG A;  4YPX A;  3NK7 A;  4E8B A;  4YQN A;  1J85 A;  1GZ0 A;  1OY5 A;  1X7P A;  5GMB A;  1NXZ A;  4J3C A;  4YQP A;  4YQD A;  5CO4 A;  4MCC A;  4YPZ A;  3IEF A;  2CX8 A;  1IPA A;  1VHK A;  1Z85 A;  3BBH A;  1VH0 A;  4JAK A;  2EGV A;  4YQ6 A;  1ZJR A;  3GYQ A;  4YQQ A;  4L69 A;  4KGN A;  4YQS A;  5GMC A;  1V2X A;  3AI9 X;  2QWV A;  4MCB A;  4YQL A;  4YVH A;  2HA8 A;  4YQC A;  3KY7 A;  3KW2 A;  4IG6 A;  5FAI A;  1NS5 A;  4YQ4 A;  4H3Y A;  3BBD A;  4YVK A;  3OII A;  2V3J A;  2Z0Y A;  3ONP A;  2V3K A;  3ILK A;  4YQ0 A;  4CNG A;  4PZK A;  3OIN A;  3AIA A;  3AXZ A;  2QMM A;  4JAL A;  3E5Y A;  2I6D A;  4JWF A;  4YQJ A;  4YQ3 A;  4KDZ A;  2YY8 A;  4YQ2 A;  4YQO A;  4YPW A; 
#chains in the Genus database with same CATH homology
 4JWJ A;  4YVJ A;  4XBO A;  4YQ5 A;  4X3L A;  3N4K A;  4X3M A;  3IC6 A;  1MXI A;  4YVI A;  3KNU A;  3O7B A;  4YQ7 A;  2O3A A;  4H3Z A;  4JWG A;  1UAK A;  4CNF A;  4YQT A;  5GM8 A;  4YQ8 A;  3L8U A;  4YQ9 A;  4MCD A;  3BBE A;  1UAJ A;  4FMW A;  4FAK A;  2EGW A;  4YQ1 A;  1V6Z A;  4CND A;  1UAM A;  1P9P A;  1K3R A;  3KTY A;  4YQK A;  1VHY A;  3DCM X;  4YQG A;  4YQI A;  1TO0 A;  3OIJ A;  4YPY A;  4YQR A;  1O6D A;  5D9F A;  4CNE A;  1X7O A;  4YQB A;  4JWH A;  3QUV A;  3N4J A;  4RG1 A;  1UAL A;  4YQA A;  3NK6 A;  4YVG A;  4YPX A;  3NK7 A;  4E8B A;  4YQN A;  1J85 A;  1GZ0 A;  1OY5 A;  1X7P A;  5GMB A;  1NXZ A;  4J3C A;  4YQP A;  4YQD A;  5CO4 A;  4MCC A;  4YPZ A;  3IEF A;  2CX8 A;  1IPA A;  1VHK A;  1Z85 A;  3BBH A;  1VH0 A;  4JAK A;  2EGV A;  4YQ6 A;  1ZJR A;  3GYQ A;  4YQQ A;  4L69 A;  4KGN A;  4YQS A;  5GMC A;  1V2X A;  3AI9 X;  2QWV A;  4MCB A;  4YQL A;  4YVH A;  2HA8 A;  4YQC A;  3KY7 A;  3KW2 A;  4IG6 A;  5FAI A;  1NS5 A;  4YQ4 A;  4H3Y A;  3BBD A;  4YVK A;  3OII A;  2V3J A;  2Z0Y A;  3ONP A;  2V3K A;  3ILK A;  4YQ0 A;  4CNG A;  4PZK A;  3OIN A;  3AIA A;  3AXZ A;  2QMM A;  4JAL A;  3E5Y A;  2I6D A;  4JWF A;  4YQJ A;  4YQ3 A;  4KDZ A;  2YY8 A;  4YQ2 A;  4YQO A;  4YPW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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