2HA8A

Methyltransferase domain of human tar (hiv-1) rna binding protein 1
Total Genus 57
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
Knots found
sequence length
159
structure length
159
Chain Sequence
LGKSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWLPLVEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQYCFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The Crystal Structure of Methyltransferase Domain of Human TAR (HIV-1) RNA binding protein 1 in complex with S-adenosyl-L-homocystein.
rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords TAR (HIV-1) RNA loop binding protein
total genus 57
structure length 159
sequence length 159
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature
pdb deposition date 2006-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2ha8A01
1X7OA 2EGVA 4YQ4A 4H3YA 1MXIA 1V2XA 1IPAA 4J3CA 1P9PA 5GM8A 5CO4A 4YQ2A 2QWVA 4JAKA 4YQJA 4YQ6A 1K3RA 5D9FA 3KW2A 1J85A 4RG1A 1NS5A 1V6ZA 3KTYA 3BBDA 3BBEA 4YQPA 4YQCA 1UAJA 4E8BA 1GZ0A 4XBOA 4YQKA 4L69A 3IEFA 3OINA 2V3JA 2O3AA 4YPYA 1VH0A 3N4KA 1NXZA 4YQAA 4KDZA 1UAKA 4YQSA 4YPXA 4YVKA 4YVGA 1UAMA 3ILKA 4IG6A 1VHKA 3KY7A 2HA8A 4YQ9A 4YQ5A 4YQIA 1TO0A 3ONPA 4YVJA 1VHYA 1ZJRA 4YQLA 4YPZA 4CNGA 4YQOA 3OIJA 3E5YA 4CNEA 2Z0YA 3DCMX 4X3LA 5GMCA 5GMBA 4MCBA 3AIAA 4JALA 4YQNA 2V3KA 4MCCA 4X3MA 3BBHA 4PZKA 3NK7A 3AXZA 1O6DA 4YVHA 4FAKA 2I6DA 3L8UA 4YQQA 4YVIA 2YY8A 3KNUA 3O7BA 4YQBA 3OIIA 1X7PA 4CNFA 4YQ7A 4YQTA 2QMMA 3N4JA 4CNDA 4MCDA 4H3ZA 4YQ1A 4YQDA 1OY5A 1Z85A 1UALA 3NK6A 4YPWA 4YQGA 4KGNA 3IC6A 3AI9X 3GYQA 5FAIA 4YQ3A 3QUVA 2CX8A 4YQ0A 2EGWA 4YQ8A 4YQRA
chains in the Genus database with same CATH superfamily
1X7OA 2EGVA 4YQ4A 4H3YA 1MXIA 1V2XA 1IPAA 4J3CA 1P9PA 5GM8A 5CO4A 4YQ2A 4FMWA 2QWVA 4JAKA 4YQJA 4YQ6A 1K3RA 5D9FA 3KW2A 1J85A 4RG1A 1NS5A 1V6ZA 3KTYA 3BBDA 3BBEA 4YQPA 4JWHA 4YQCA 1UAJA 4E8BA 1GZ0A 4XBOA 4YQKA 4L69A 3IEFA 3OINA 2V3JA 2O3AA 4YPYA 1VH0A 3N4KA 1NXZA 4YQAA 4KDZA 1UAKA 4YQSA 4YPXA 4YVKA 4JWJA 4YVGA 1UAMA 3ILKA 4IG6A 1VHKA 3KY7A 2HA8A 4YQ9A 4YQ5A 4YQIA 1TO0A 3ONPA 4YVJA 1VHYA 1ZJRA 4YQLA 4YPZA 4CNGA 4YQOA 3OIJA 3E5YA 4CNEA 2Z0YA 3DCMX 4X3LA 5GMCA 5GMBA 4MCBA 3AIAA 4JALA 4YQNA 2V3KA 4MCCA 4X3MA 3BBHA 4JWGA 4PZKA 3NK7A 4JWFA 3AXZA 1O6DA 4YVHA 4FAKA 2I6DA 3L8UA 4YQQA 4YVIA 2YY8A 3KNUA 3O7BA 4YQBA 3OIIA 1X7PA 4CNFA 4YQ7A 4YQTA 2QMMA 3N4JA 4CNDA 4MCDA 4H3ZA 4YQ1A 4YQDA 1OY5A 1Z85A 1UALA 3NK6A 4YPWA 4YQGA 4KGNA 3IC6A 3AI9X 3GYQA 5FAIA 4YQ3A 3QUVA 2CX8A 4YQ0A 2EGWA 4YQ8A 4YQRA
chains in the Genus database with same CATH topology
1X7OA 2EGVA 4YQ4A 4H3YA 1MXIA 1V2XA 1IPAA 4J3CA 1P9PA 5GM8A 5CO4A 4YQ2A 4FMWA 2QWVA 4JAKA 4YQJA 4YQ6A 1K3RA 5D9FA 3KW2A 1J85A 4RG1A 1NS5A 1V6ZA 3KTYA 3BBDA 3BBEA 4YQPA 4JWHA 4YQCA 1UAJA 4E8BA 1GZ0A 4XBOA 4YQKA 4L69A 3IEFA 3OINA 2V3JA 2O3AA 4YPYA 1VH0A 3N4KA 1NXZA 4YQAA 4KDZA 1UAKA 4YQSA 4YPXA 4YVKA 4JWJA 4YVGA 1UAMA 3ILKA 4IG6A 1VHKA 3KY7A 2HA8A 4YQ9A 4YQ5A 4YQIA 1TO0A 3ONPA 4YVJA 1VHYA 1ZJRA 4YQLA 4YPZA 4CNGA 4YQOA 3OIJA 3E5YA 4CNEA 2Z0YA 3DCMX 4X3LA 5GMCA 5GMBA 4MCBA 3AIAA 4JALA 4YQNA 2V3KA 4MCCA 4X3MA 3BBHA 4JWGA 4PZKA 3NK7A 4JWFA 3AXZA 1O6DA 4YVHA 4FAKA 2I6DA 3L8UA 4YQQA 4YVIA 2YY8A 3KNUA 3O7BA 4YQBA 3OIIA 1X7PA 4CNFA 4YQ7A 4YQTA 2QMMA 3N4JA 4CNDA 4MCDA 4H3ZA 4YQ1A 4YQDA 1OY5A 1Z85A 1UALA 3NK6A 4YPWA 4YQGA 4KGNA 3IC6A 3AI9X 3GYQA 5FAIA 4YQ3A 3QUVA 2CX8A 4YQ0A 2EGWA 4YQ8A 4YQRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X7O A;  2EGV A;  4YQ4 A;  4H3Y A;  1MXI A;  1V2X A;  1IPA A;  4J3C A;  1P9P A;  5GM8 A;  5CO4 A;  4YQ2 A;  2QWV A;  4JAK A;  4YQJ A;  4YQ6 A;  1K3R A;  5D9F A;  3KW2 A;  1J85 A;  4RG1 A;  1NS5 A;  1V6Z A;  3KTY A;  3BBD A;  3BBE A;  4YQP A;  4YQC A;  1UAJ A;  4E8B A;  1GZ0 A;  4XBO A;  4YQK A;  4L69 A;  3IEF A;  3OIN A;  2V3J A;  2O3A A;  4YPY A;  1VH0 A;  3N4K A;  1NXZ A;  4YQA A;  4KDZ A;  1UAK A;  4YQS A;  4YPX A;  4YVK A;  4YVG A;  1UAM A;  3ILK A;  4IG6 A;  1VHK A;  3KY7 A;  2HA8 A;  4YQ9 A;  4YQ5 A;  4YQI A;  1TO0 A;  3ONP A;  4YVJ A;  1VHY A;  1ZJR A;  4YQL A;  4YPZ A;  4CNG A;  4YQO A;  3OIJ A;  3E5Y A;  4CNE A;  2Z0Y A;  3DCM X;  4X3L A;  5GMC A;  5GMB A;  4MCB A;  3AIA A;  4JAL A;  4YQN A;  2V3K A;  4MCC A;  4X3M A;  3BBH A;  4PZK A;  3NK7 A;  3AXZ A;  1O6D A;  4YVH A;  4FAK A;  2I6D A;  3L8U A;  4YQQ A;  4YVI A;  2YY8 A;  3KNU A;  3O7B A;  4YQB A;  3OII A;  1X7P A;  4CNF A;  4YQ7 A;  4YQT A;  2QMM A;  3N4J A;  4CND A;  4MCD A;  4H3Z A;  4YQ1 A;  4YQD A;  1OY5 A;  1Z85 A;  1UAL A;  3NK6 A;  4YPW A;  4YQG A;  4KGN A;  3IC6 A;  3AI9 X;  3GYQ A;  5FAI A;  4YQ3 A;  3QUV A;  2CX8 A;  4YQ0 A;  2EGW A;  4YQ8 A;  4YQR A; 
#chains in the Genus database with same CATH topology
 1X7O A;  2EGV A;  4YQ4 A;  4H3Y A;  1MXI A;  1V2X A;  1IPA A;  4J3C A;  1P9P A;  5GM8 A;  5CO4 A;  4YQ2 A;  4FMW A;  2QWV A;  4JAK A;  4YQJ A;  4YQ6 A;  1K3R A;  5D9F A;  3KW2 A;  1J85 A;  4RG1 A;  1NS5 A;  1V6Z A;  3KTY A;  3BBD A;  3BBE A;  4YQP A;  4JWH A;  4YQC A;  1UAJ A;  4E8B A;  1GZ0 A;  4XBO A;  4YQK A;  4L69 A;  3IEF A;  3OIN A;  2V3J A;  2O3A A;  4YPY A;  1VH0 A;  3N4K A;  1NXZ A;  4YQA A;  4KDZ A;  1UAK A;  4YQS A;  4YPX A;  4YVK A;  4JWJ A;  4YVG A;  1UAM A;  3ILK A;  4IG6 A;  1VHK A;  3KY7 A;  2HA8 A;  4YQ9 A;  4YQ5 A;  4YQI A;  1TO0 A;  3ONP A;  4YVJ A;  1VHY A;  1ZJR A;  4YQL A;  4YPZ A;  4CNG A;  4YQO A;  3OIJ A;  3E5Y A;  4CNE A;  2Z0Y A;  3DCM X;  4X3L A;  5GMC A;  5GMB A;  4MCB A;  3AIA A;  4JAL A;  4YQN A;  2V3K A;  4MCC A;  4X3M A;  3BBH A;  4JWG A;  4PZK A;  3NK7 A;  4JWF A;  3AXZ A;  1O6D A;  4YVH A;  4FAK A;  2I6D A;  3L8U A;  4YQQ A;  4YVI A;  2YY8 A;  3KNU A;  3O7B A;  4YQB A;  3OII A;  1X7P A;  4CNF A;  4YQ7 A;  4YQT A;  2QMM A;  3N4J A;  4CND A;  4MCD A;  4H3Z A;  4YQ1 A;  4YQD A;  1OY5 A;  1Z85 A;  1UAL A;  3NK6 A;  4YPW A;  4YQG A;  4KGN A;  3IC6 A;  3AI9 X;  3GYQ A;  5FAI A;  4YQ3 A;  3QUV A;  2CX8 A;  4YQ0 A;  2EGW A;  4YQ8 A;  4YQR A; 
#chains in the Genus database with same CATH homology
 1X7O A;  2EGV A;  4YQ4 A;  4H3Y A;  1MXI A;  1V2X A;  1IPA A;  4J3C A;  1P9P A;  5GM8 A;  5CO4 A;  4YQ2 A;  4FMW A;  2QWV A;  4JAK A;  4YQJ A;  4YQ6 A;  1K3R A;  5D9F A;  3KW2 A;  1J85 A;  4RG1 A;  1NS5 A;  1V6Z A;  3KTY A;  3BBD A;  3BBE A;  4YQP A;  4JWH A;  4YQC A;  1UAJ A;  4E8B A;  1GZ0 A;  4XBO A;  4YQK A;  4L69 A;  3IEF A;  3OIN A;  2V3J A;  2O3A A;  4YPY A;  1VH0 A;  3N4K A;  1NXZ A;  4YQA A;  4KDZ A;  1UAK A;  4YQS A;  4YPX A;  4YVK A;  4JWJ A;  4YVG A;  1UAM A;  3ILK A;  4IG6 A;  1VHK A;  3KY7 A;  2HA8 A;  4YQ9 A;  4YQ5 A;  4YQI A;  1TO0 A;  3ONP A;  4YVJ A;  1VHY A;  1ZJR A;  4YQL A;  4YPZ A;  4CNG A;  4YQO A;  3OIJ A;  3E5Y A;  4CNE A;  2Z0Y A;  3DCM X;  4X3L A;  5GMC A;  5GMB A;  4MCB A;  3AIA A;  4JAL A;  4YQN A;  2V3K A;  4MCC A;  4X3M A;  3BBH A;  4JWG A;  4PZK A;  3NK7 A;  4JWF A;  3AXZ A;  1O6D A;  4YVH A;  4FAK A;  2I6D A;  3L8U A;  4YQQ A;  4YVI A;  2YY8 A;  3KNU A;  3O7B A;  4YQB A;  3OII A;  1X7P A;  4CNF A;  4YQ7 A;  4YQT A;  2QMM A;  3N4J A;  4CND A;  4MCD A;  4H3Z A;  4YQ1 A;  4YQD A;  1OY5 A;  1Z85 A;  1UAL A;  3NK6 A;  4YPW A;  4YQG A;  4KGN A;  3IC6 A;  3AI9 X;  3GYQ A;  5FAI A;  4YQ3 A;  3QUV A;  2CX8 A;  4YQ0 A;  2EGW A;  4YQ8 A;  4YQR A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...