2V3KA

The yeast ribosome synthesis factor emg1 alpha beta knot fold methyltransferase
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
Knots found
sequence length
227
structure length
218
Chain Sequence
PQAPPVLTSKDKITKRMIVVLAMASLETHKIYVLLNCDDHQGLLKKMGRDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Yeast Ribosome Synthesis Factor Emg1 is a Novel Member of the Superfamily of Alpha/Beta Knot Fold Methyltransferases.
pubmed doi rcsb
molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
molecule keywords ESSENTIAL FOR MITOTIC GROWTH 1
total genus 58
structure length 218
sequence length 227
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2007-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2v3kA01
2QWVA 4CNGA 2QMMA 4YQ3A 1V6ZA 4YQDA 4IG6A 4YQOA 2EGVA 1Z85A 4YQBA 3NK6A 4J3CA 4YQIA 4MCBA 4KGNA 2V3JA 4YQ0A 1UAJA 4XBOA 1X7OA 1O6DA 4YQLA 2EGWA 4YQ8A 4YQ5A 4YQPA 3O7BA 3OIIA 4YQ4A 3BBEA 3OIJA 3KNUA 1NXZA 3KW2A 1TO0A 4JALA 4YQ2A 1P9PA 4PZKA 3BBDA 3NK7A 5FAIA 1NS5A 4X3MA 4YQCA 1UALA 1VH0A 5D9FA 4KDZA 4YQTA 1MXIA 1K3RA 1VHYA 4YQQA 4YVKA 3E5YA 2YY8A 4YQSA 1GZ0A 4H3YA 4CNDA 1VHKA 4YVGA 3AXZA 3AI9X 4JAKA 2O3AA 3ONPA 3AIAA 3DCMX 3KTYA 4YQJA 4MCDA 1X7PA 3BBHA 3IC6A 3ILKA 4YQKA 3N4JA 5GM8A 4CNFA 3OINA 2HA8A 1J85A 4X3LA 4FAKA 4YVJA 4YQAA 2I6DA 4YPXA 4H3ZA 3GYQA 2CX8A 1UAKA 5GMCA 5CO4A 3IEFA 1OY5A 4YQ6A 4L69A 1IPAA 5GMBA 4E8BA 4YQ9A 4YVHA 2V3KA 4RG1A 4YQ7A 4YQGA 3QUVA 3N4KA 4YPYA 4YVIA 4MCCA 4YPZA 1ZJRA 4YPWA 4YQNA 1V2XA 2Z0YA 3KY7A 4YQ1A 4YQRA 1UAMA 4CNEA 3L8UA
chains in the Genus database with same CATH superfamily
2QWVA 4CNGA 2QMMA 4YQ3A 1V6ZA 4YQDA 4IG6A 4YQOA 2EGVA 1Z85A 4YQBA 3NK6A 4J3CA 4YQIA 4MCBA 4KGNA 2V3JA 4YQ0A 1UAJA 4XBOA 1X7OA 1O6DA 4YQLA 2EGWA 4YQ8A 4YQ5A 4JWJA 4YQPA 3O7BA 3OIIA 4YQ4A 3BBEA 3OIJA 3KNUA 1NXZA 3KW2A 1TO0A 4JALA 4YQ2A 1P9PA 4PZKA 3BBDA 3NK7A 5FAIA 1NS5A 4JWHA 4X3MA 4YQCA 1UALA 1VH0A 5D9FA 4KDZA 4YQTA 1MXIA 1K3RA 1VHYA 4YQQA 4YVKA 3E5YA 2YY8A 4YQSA 1GZ0A 4H3YA 4CNDA 4JWFA 1VHKA 4YVGA 3AXZA 3AI9X 4JAKA 2O3AA 3ONPA 3AIAA 3DCMX 3KTYA 4YQJA 4MCDA 4FMWA 1X7PA 3BBHA 3IC6A 3ILKA 4YQKA 3N4JA 5GM8A 4CNFA 3OINA 2HA8A 1J85A 4JWGA 4X3LA 4FAKA 4YVJA 4YQAA 2I6DA 4YPXA 4H3ZA 3GYQA 2CX8A 1UAKA 5GMCA 5CO4A 3IEFA 1OY5A 4YQ6A 4L69A 1IPAA 5GMBA 4E8BA 4YQ9A 4YVHA 2V3KA 4RG1A 4YQ7A 4YQGA 3QUVA 3N4KA 4YPYA 4YVIA 4MCCA 4YPZA 1ZJRA 4YPWA 4YQNA 1V2XA 2Z0YA 3KY7A 4YQ1A 4YQRA 1UAMA 4CNEA 3L8UA
chains in the Genus database with same CATH topology
2QWVA 4CNGA 2QMMA 4YQ3A 1V6ZA 4YQDA 4IG6A 4YQOA 2EGVA 1Z85A 4YQBA 3NK6A 4J3CA 4YQIA 4MCBA 4KGNA 2V3JA 4YQ0A 1UAJA 4XBOA 1X7OA 1O6DA 4YQLA 2EGWA 4YQ8A 4YQ5A 4JWJA 4YQPA 3O7BA 3OIIA 4YQ4A 3BBEA 3OIJA 3KNUA 1NXZA 3KW2A 1TO0A 4JALA 4YQ2A 1P9PA 4PZKA 3BBDA 3NK7A 5FAIA 1NS5A 4JWHA 4X3MA 4YQCA 1UALA 1VH0A 5D9FA 4KDZA 4YQTA 1MXIA 1K3RA 1VHYA 4YQQA 4YVKA 3E5YA 2YY8A 4YQSA 1GZ0A 4H3YA 4CNDA 4JWFA 1VHKA 4YVGA 3AXZA 3AI9X 4JAKA 2O3AA 3ONPA 3AIAA 3DCMX 3KTYA 4YQJA 4MCDA 4FMWA 1X7PA 3BBHA 3IC6A 3ILKA 4YQKA 3N4JA 5GM8A 4CNFA 3OINA 2HA8A 1J85A 4JWGA 4X3LA 4FAKA 4YVJA 4YQAA 2I6DA 4YPXA 4H3ZA 3GYQA 2CX8A 1UAKA 5GMCA 5CO4A 3IEFA 1OY5A 4YQ6A 4L69A 1IPAA 5GMBA 4E8BA 4YQ9A 4YVHA 2V3KA 4RG1A 4YQ7A 4YQGA 3QUVA 3N4KA 4YPYA 4YVIA 4MCCA 4YPZA 1ZJRA 4YPWA 4YQNA 1V2XA 2Z0YA 3KY7A 4YQ1A 4YQRA 1UAMA 4CNEA 3L8UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QWV A;  4CNG A;  2QMM A;  4YQ3 A;  1V6Z A;  4YQD A;  4IG6 A;  4YQO A;  2EGV A;  1Z85 A;  4YQB A;  3NK6 A;  4J3C A;  4YQI A;  4MCB A;  4KGN A;  2V3J A;  4YQ0 A;  1UAJ A;  4XBO A;  1X7O A;  1O6D A;  4YQL A;  2EGW A;  4YQ8 A;  4YQ5 A;  4YQP A;  3O7B A;  3OII A;  4YQ4 A;  3BBE A;  3OIJ A;  3KNU A;  1NXZ A;  3KW2 A;  1TO0 A;  4JAL A;  4YQ2 A;  1P9P A;  4PZK A;  3BBD A;  3NK7 A;  5FAI A;  1NS5 A;  4X3M A;  4YQC A;  1UAL A;  1VH0 A;  5D9F A;  4KDZ A;  4YQT A;  1MXI A;  1K3R A;  1VHY A;  4YQQ A;  4YVK A;  3E5Y A;  2YY8 A;  4YQS A;  1GZ0 A;  4H3Y A;  4CND A;  1VHK A;  4YVG A;  3AXZ A;  3AI9 X;  4JAK A;  2O3A A;  3ONP A;  3AIA A;  3DCM X;  3KTY A;  4YQJ A;  4MCD A;  1X7P A;  3BBH A;  3IC6 A;  3ILK A;  4YQK A;  3N4J A;  5GM8 A;  4CNF A;  3OIN A;  2HA8 A;  1J85 A;  4X3L A;  4FAK A;  4YVJ A;  4YQA A;  2I6D A;  4YPX A;  4H3Z A;  3GYQ A;  2CX8 A;  1UAK A;  5GMC A;  5CO4 A;  3IEF A;  1OY5 A;  4YQ6 A;  4L69 A;  1IPA A;  5GMB A;  4E8B A;  4YQ9 A;  4YVH A;  2V3K A;  4RG1 A;  4YQ7 A;  4YQG A;  3QUV A;  3N4K A;  4YPY A;  4YVI A;  4MCC A;  4YPZ A;  1ZJR A;  4YPW A;  4YQN A;  1V2X A;  2Z0Y A;  3KY7 A;  4YQ1 A;  4YQR A;  1UAM A;  4CNE A;  3L8U A; 
#chains in the Genus database with same CATH topology
 2QWV A;  4CNG A;  2QMM A;  4YQ3 A;  1V6Z A;  4YQD A;  4IG6 A;  4YQO A;  2EGV A;  1Z85 A;  4YQB A;  3NK6 A;  4J3C A;  4YQI A;  4MCB A;  4KGN A;  2V3J A;  4YQ0 A;  1UAJ A;  4XBO A;  1X7O A;  1O6D A;  4YQL A;  2EGW A;  4YQ8 A;  4YQ5 A;  4JWJ A;  4YQP A;  3O7B A;  3OII A;  4YQ4 A;  3BBE A;  3OIJ A;  3KNU A;  1NXZ A;  3KW2 A;  1TO0 A;  4JAL A;  4YQ2 A;  1P9P A;  4PZK A;  3BBD A;  3NK7 A;  5FAI A;  1NS5 A;  4JWH A;  4X3M A;  4YQC A;  1UAL A;  1VH0 A;  5D9F A;  4KDZ A;  4YQT A;  1MXI A;  1K3R A;  1VHY A;  4YQQ A;  4YVK A;  3E5Y A;  2YY8 A;  4YQS A;  1GZ0 A;  4H3Y A;  4CND A;  4JWF A;  1VHK A;  4YVG A;  3AXZ A;  3AI9 X;  4JAK A;  2O3A A;  3ONP A;  3AIA A;  3DCM X;  3KTY A;  4YQJ A;  4MCD A;  4FMW A;  1X7P A;  3BBH A;  3IC6 A;  3ILK A;  4YQK A;  3N4J A;  5GM8 A;  4CNF A;  3OIN A;  2HA8 A;  1J85 A;  4JWG A;  4X3L A;  4FAK A;  4YVJ A;  4YQA A;  2I6D A;  4YPX A;  4H3Z A;  3GYQ A;  2CX8 A;  1UAK A;  5GMC A;  5CO4 A;  3IEF A;  1OY5 A;  4YQ6 A;  4L69 A;  1IPA A;  5GMB A;  4E8B A;  4YQ9 A;  4YVH A;  2V3K A;  4RG1 A;  4YQ7 A;  4YQG A;  3QUV A;  3N4K A;  4YPY A;  4YVI A;  4MCC A;  4YPZ A;  1ZJR A;  4YPW A;  4YQN A;  1V2X A;  2Z0Y A;  3KY7 A;  4YQ1 A;  4YQR A;  1UAM A;  4CNE A;  3L8U A; 
#chains in the Genus database with same CATH homology
 2QWV A;  4CNG A;  2QMM A;  4YQ3 A;  1V6Z A;  4YQD A;  4IG6 A;  4YQO A;  2EGV A;  1Z85 A;  4YQB A;  3NK6 A;  4J3C A;  4YQI A;  4MCB A;  4KGN A;  2V3J A;  4YQ0 A;  1UAJ A;  4XBO A;  1X7O A;  1O6D A;  4YQL A;  2EGW A;  4YQ8 A;  4YQ5 A;  4JWJ A;  4YQP A;  3O7B A;  3OII A;  4YQ4 A;  3BBE A;  3OIJ A;  3KNU A;  1NXZ A;  3KW2 A;  1TO0 A;  4JAL A;  4YQ2 A;  1P9P A;  4PZK A;  3BBD A;  3NK7 A;  5FAI A;  1NS5 A;  4JWH A;  4X3M A;  4YQC A;  1UAL A;  1VH0 A;  5D9F A;  4KDZ A;  4YQT A;  1MXI A;  1K3R A;  1VHY A;  4YQQ A;  4YVK A;  3E5Y A;  2YY8 A;  4YQS A;  1GZ0 A;  4H3Y A;  4CND A;  4JWF A;  1VHK A;  4YVG A;  3AXZ A;  3AI9 X;  4JAK A;  2O3A A;  3ONP A;  3AIA A;  3DCM X;  3KTY A;  4YQJ A;  4MCD A;  4FMW A;  1X7P A;  3BBH A;  3IC6 A;  3ILK A;  4YQK A;  3N4J A;  5GM8 A;  4CNF A;  3OIN A;  2HA8 A;  1J85 A;  4JWG A;  4X3L A;  4FAK A;  4YVJ A;  4YQA A;  2I6D A;  4YPX A;  4H3Z A;  3GYQ A;  2CX8 A;  1UAK A;  5GMC A;  5CO4 A;  3IEF A;  1OY5 A;  4YQ6 A;  4L69 A;  1IPA A;  5GMB A;  4E8B A;  4YQ9 A;  4YVH A;  2V3K A;  4RG1 A;  4YQ7 A;  4YQG A;  3QUV A;  3N4K A;  4YPY A;  4YVI A;  4MCC A;  4YPZ A;  1ZJR A;  4YPW A;  4YQN A;  1V2X A;  2Z0Y A;  3KY7 A;  4YQ1 A;  4YQR A;  1UAM A;  4CNE A;  3L8U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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