2YY8A

Crystal structure of archaeal trna-methylase for position 56 (atrm56) from pyrococcus horikoshii, complexed with s-adenosyl-l-methionine
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
Knots found
sequence length
175
structure length
174
Chain Sequence
MIVVLRLGHRPEDKRVTTHVALTARAFGADGIIIASEEDEKVKESVEDVVKRWGGPFFIEFNRNWRKVMKEFTGVKVHLTMYGLHVDDVIEELKEKLKKGEDFMIIVGAEKVPREVYELADYNVAIGNQPHSEVAALAVLLDRLLEGKGLKKEFKGAKIKIVPQARGKKVVEVQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA
pubmed doi rcsb
molecule tags Transferase
source organism Pyrococcus horikoshii
molecule keywords UPF0106 protein PH0461
total genus 54
structure length 174
sequence length 175
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.206: tRNA (cytidine(56)-2'-O)-methyltransferase.
pdb deposition date 2007-04-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01994 Trm56 tRNA ribose 2'-O-methyltransferase, aTrm56
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2yy8A00
4CNEA 4YQ6A 1VHKA 4YQ7A 4YQAA 4YQ9A 2O3AA 1OY5A 4YQ2A 3KTYA 5D9FA 2EGVA 4YVGA 4JAKA 4CNFA 4YPXA 2V3JA 4YQ3A 3DCMX 3AIAA 4JALA 2QWVA 4RG1A 4YQ1A 1UALA 4YQKA 5FAIA 4YQ5A 5GMBA 4X3MA 3NK6A 1VH0A 4YPZA 4PZKA 3AI9X 4YQGA 5CO4A 1MXIA 2YY8A 4H3YA 4YQSA 4CNGA 1V2XA 4YQDA 3OIJA 3IEFA 2CX8A 1V6ZA 3AXZA 4MCCA 2Z0YA 1ZJRA 3L8UA 1TO0A 3OIIA 4XBOA 1J85A 3BBHA 3OINA 3E5YA 4YVJA 2EGWA 1X7PA 3GYQA 4YVKA 1P9PA 2I6DA 4YQJA 3O7BA 4YQRA 1VHYA 4L69A 4YVIA 4YQPA 4KGNA 4CNDA 3BBDA 4X3LA 1NS5A 3KNUA 3KY7A 1X7OA 1K3RA 4MCBA 4YQOA 4YQBA 1NXZA 1Z85A 1O6DA 4IG6A 4YPWA 5GM8A 3NK7A 4YQ0A 3ILKA 4FAKA 4YQ8A 3IC6A 5GMCA 2V3KA 1IPAA 3BBEA 4YQCA 4YQQA 3KW2A 3N4KA 4YPYA 4YQNA 4KDZA 4H3ZA 3ONPA 4MCDA 4YQTA 1UAJA 4YVHA 1UAKA 3QUVA 2HA8A 4YQ4A 4YQIA 1GZ0A 4YQLA 4J3CA 4E8BA 3N4JA 1UAMA 2QMMA
chains in the Genus database with same CATH superfamily
4CNEA 4YQ6A 1VHKA 4YQ7A 4YQAA 4YQ9A 2O3AA 1OY5A 4YQ2A 3KTYA 5D9FA 2EGVA 4YVGA 4JAKA 4CNFA 4YPXA 2V3JA 4YQ3A 3DCMX 3AIAA 4JALA 2QWVA 4RG1A 4YQ1A 1UALA 4YQKA 5FAIA 4YQ5A 5GMBA 4X3MA 3NK6A 4FMWA 1VH0A 4YPZA 4PZKA 3AI9X 4YQGA 5CO4A 1MXIA 2YY8A 4H3YA 4YQSA 4CNGA 1V2XA 4YQDA 3OIJA 3IEFA 2CX8A 1V6ZA 3AXZA 4JWGA 4MCCA 2Z0YA 1ZJRA 3L8UA 1TO0A 3OIIA 4XBOA 1J85A 3BBHA 3OINA 3E5YA 4YVJA 2EGWA 1X7PA 3GYQA 4YVKA 1P9PA 2I6DA 4YQJA 3O7BA 4YQRA 1VHYA 4L69A 4YVIA 4YQPA 4KGNA 4CNDA 3BBDA 4X3LA 1NS5A 3KNUA 3KY7A 1X7OA 1K3RA 4MCBA 4YQOA 4YQBA 1NXZA 1Z85A 1O6DA 4JWFA 4IG6A 4YPWA 5GM8A 3NK7A 4YQ0A 4JWHA 3ILKA 4FAKA 4YQ8A 3IC6A 5GMCA 2V3KA 1IPAA 3BBEA 4YQCA 4YQQA 3KW2A 3N4KA 4YPYA 4YQNA 4JWJA 4KDZA 4H3ZA 3ONPA 4MCDA 4YQTA 1UAJA 4YVHA 1UAKA 3QUVA 2HA8A 4YQ4A 4YQIA 1GZ0A 4YQLA 4J3CA 4E8BA 3N4JA 1UAMA 2QMMA
chains in the Genus database with same CATH topology
4CNEA 4YQ6A 1VHKA 4YQ7A 4YQAA 4YQ9A 2O3AA 1OY5A 4YQ2A 3KTYA 5D9FA 2EGVA 4YVGA 4JAKA 4CNFA 4YPXA 2V3JA 4YQ3A 3DCMX 3AIAA 4JALA 2QWVA 4RG1A 4YQ1A 1UALA 4YQKA 5FAIA 4YQ5A 5GMBA 4X3MA 3NK6A 4FMWA 1VH0A 4YPZA 4PZKA 3AI9X 4YQGA 5CO4A 1MXIA 2YY8A 4H3YA 4YQSA 4CNGA 1V2XA 4YQDA 3OIJA 3IEFA 2CX8A 1V6ZA 3AXZA 4JWGA 4MCCA 2Z0YA 1ZJRA 3L8UA 1TO0A 3OIIA 4XBOA 1J85A 3BBHA 3OINA 3E5YA 4YVJA 2EGWA 1X7PA 3GYQA 4YVKA 1P9PA 2I6DA 4YQJA 3O7BA 4YQRA 1VHYA 4L69A 4YVIA 4YQPA 4KGNA 4CNDA 3BBDA 4X3LA 1NS5A 3KNUA 3KY7A 1X7OA 1K3RA 4MCBA 4YQOA 4YQBA 1NXZA 1Z85A 1O6DA 4JWFA 4IG6A 4YPWA 5GM8A 3NK7A 4YQ0A 4JWHA 3ILKA 4FAKA 4YQ8A 3IC6A 5GMCA 2V3KA 1IPAA 3BBEA 4YQCA 4YQQA 3KW2A 3N4KA 4YPYA 4YQNA 4JWJA 4KDZA 4H3ZA 3ONPA 4MCDA 4YQTA 1UAJA 4YVHA 1UAKA 3QUVA 2HA8A 4YQ4A 4YQIA 1GZ0A 4YQLA 4J3CA 4E8BA 3N4JA 1UAMA 2QMMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CNE A;  4YQ6 A;  1VHK A;  4YQ7 A;  4YQA A;  4YQ9 A;  2O3A A;  1OY5 A;  4YQ2 A;  3KTY A;  5D9F A;  2EGV A;  4YVG A;  4JAK A;  4CNF A;  4YPX A;  2V3J A;  4YQ3 A;  3DCM X;  3AIA A;  4JAL A;  2QWV A;  4RG1 A;  4YQ1 A;  1UAL A;  4YQK A;  5FAI A;  4YQ5 A;  5GMB A;  4X3M A;  3NK6 A;  1VH0 A;  4YPZ A;  4PZK A;  3AI9 X;  4YQG A;  5CO4 A;  1MXI A;  2YY8 A;  4H3Y A;  4YQS A;  4CNG A;  1V2X A;  4YQD A;  3OIJ A;  3IEF A;  2CX8 A;  1V6Z A;  3AXZ A;  4MCC A;  2Z0Y A;  1ZJR A;  3L8U A;  1TO0 A;  3OII A;  4XBO A;  1J85 A;  3BBH A;  3OIN A;  3E5Y A;  4YVJ A;  2EGW A;  1X7P A;  3GYQ A;  4YVK A;  1P9P A;  2I6D A;  4YQJ A;  3O7B A;  4YQR A;  1VHY A;  4L69 A;  4YVI A;  4YQP A;  4KGN A;  4CND A;  3BBD A;  4X3L A;  1NS5 A;  3KNU A;  3KY7 A;  1X7O A;  1K3R A;  4MCB A;  4YQO A;  4YQB A;  1NXZ A;  1Z85 A;  1O6D A;  4IG6 A;  4YPW A;  5GM8 A;  3NK7 A;  4YQ0 A;  3ILK A;  4FAK A;  4YQ8 A;  3IC6 A;  5GMC A;  2V3K A;  1IPA A;  3BBE A;  4YQC A;  4YQQ A;  3KW2 A;  3N4K A;  4YPY A;  4YQN A;  4KDZ A;  4H3Z A;  3ONP A;  4MCD A;  4YQT A;  1UAJ A;  4YVH A;  1UAK A;  3QUV A;  2HA8 A;  4YQ4 A;  4YQI A;  1GZ0 A;  4YQL A;  4J3C A;  4E8B A;  3N4J A;  1UAM A;  2QMM A; 
#chains in the Genus database with same CATH topology
 4CNE A;  4YQ6 A;  1VHK A;  4YQ7 A;  4YQA A;  4YQ9 A;  2O3A A;  1OY5 A;  4YQ2 A;  3KTY A;  5D9F A;  2EGV A;  4YVG A;  4JAK A;  4CNF A;  4YPX A;  2V3J A;  4YQ3 A;  3DCM X;  3AIA A;  4JAL A;  2QWV A;  4RG1 A;  4YQ1 A;  1UAL A;  4YQK A;  5FAI A;  4YQ5 A;  5GMB A;  4X3M A;  3NK6 A;  4FMW A;  1VH0 A;  4YPZ A;  4PZK A;  3AI9 X;  4YQG A;  5CO4 A;  1MXI A;  2YY8 A;  4H3Y A;  4YQS A;  4CNG A;  1V2X A;  4YQD A;  3OIJ A;  3IEF A;  2CX8 A;  1V6Z A;  3AXZ A;  4JWG A;  4MCC A;  2Z0Y A;  1ZJR A;  3L8U A;  1TO0 A;  3OII A;  4XBO A;  1J85 A;  3BBH A;  3OIN A;  3E5Y A;  4YVJ A;  2EGW A;  1X7P A;  3GYQ A;  4YVK A;  1P9P A;  2I6D A;  4YQJ A;  3O7B A;  4YQR A;  1VHY A;  4L69 A;  4YVI A;  4YQP A;  4KGN A;  4CND A;  3BBD A;  4X3L A;  1NS5 A;  3KNU A;  3KY7 A;  1X7O A;  1K3R A;  4MCB A;  4YQO A;  4YQB A;  1NXZ A;  1Z85 A;  1O6D A;  4JWF A;  4IG6 A;  4YPW A;  5GM8 A;  3NK7 A;  4YQ0 A;  4JWH A;  3ILK A;  4FAK A;  4YQ8 A;  3IC6 A;  5GMC A;  2V3K A;  1IPA A;  3BBE A;  4YQC A;  4YQQ A;  3KW2 A;  3N4K A;  4YPY A;  4YQN A;  4JWJ A;  4KDZ A;  4H3Z A;  3ONP A;  4MCD A;  4YQT A;  1UAJ A;  4YVH A;  1UAK A;  3QUV A;  2HA8 A;  4YQ4 A;  4YQI A;  1GZ0 A;  4YQL A;  4J3C A;  4E8B A;  3N4J A;  1UAM A;  2QMM A; 
#chains in the Genus database with same CATH homology
 4CNE A;  4YQ6 A;  1VHK A;  4YQ7 A;  4YQA A;  4YQ9 A;  2O3A A;  1OY5 A;  4YQ2 A;  3KTY A;  5D9F A;  2EGV A;  4YVG A;  4JAK A;  4CNF A;  4YPX A;  2V3J A;  4YQ3 A;  3DCM X;  3AIA A;  4JAL A;  2QWV A;  4RG1 A;  4YQ1 A;  1UAL A;  4YQK A;  5FAI A;  4YQ5 A;  5GMB A;  4X3M A;  3NK6 A;  4FMW A;  1VH0 A;  4YPZ A;  4PZK A;  3AI9 X;  4YQG A;  5CO4 A;  1MXI A;  2YY8 A;  4H3Y A;  4YQS A;  4CNG A;  1V2X A;  4YQD A;  3OIJ A;  3IEF A;  2CX8 A;  1V6Z A;  3AXZ A;  4JWG A;  4MCC A;  2Z0Y A;  1ZJR A;  3L8U A;  1TO0 A;  3OII A;  4XBO A;  1J85 A;  3BBH A;  3OIN A;  3E5Y A;  4YVJ A;  2EGW A;  1X7P A;  3GYQ A;  4YVK A;  1P9P A;  2I6D A;  4YQJ A;  3O7B A;  4YQR A;  1VHY A;  4L69 A;  4YVI A;  4YQP A;  4KGN A;  4CND A;  3BBD A;  4X3L A;  1NS5 A;  3KNU A;  3KY7 A;  1X7O A;  1K3R A;  4MCB A;  4YQO A;  4YQB A;  1NXZ A;  1Z85 A;  1O6D A;  4JWF A;  4IG6 A;  4YPW A;  5GM8 A;  3NK7 A;  4YQ0 A;  4JWH A;  3ILK A;  4FAK A;  4YQ8 A;  3IC6 A;  5GMC A;  2V3K A;  1IPA A;  3BBE A;  4YQC A;  4YQQ A;  3KW2 A;  3N4K A;  4YPY A;  4YQN A;  4JWJ A;  4KDZ A;  4H3Z A;  3ONP A;  4MCD A;  4YQT A;  1UAJ A;  4YVH A;  1UAK A;  3QUV A;  2HA8 A;  4YQ4 A;  4YQI A;  1GZ0 A;  4YQL A;  4J3C A;  4E8B A;  3N4J A;  1UAM A;  2QMM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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