3BEFA

Crystal structure of thrombin bound to the extracellular fragment of par1
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
44
structure length
44
Chain Sequence
SEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Prothrombin
publication title Structural identification of the pathway of long-range communication in an allosteric enzyme.
pubmed doi rcsb
source organism Homo sapiens
total genus 3
structure length 44
sequence length 44
chains with identical sequence D
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2007-11-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 3befA00
1TQ7A 2A1DA 3HKIA 1Z8JA 3HK6A 4RKOA 1JOUA 3GISA 3BEIA 3E6PL 1TBRJ 2ODYA 3BEFA 3LU9A 3B9FL 1AVGL 3EDXA 1TBQJ 1JMOL 4DY7A 2PV9A 2PGQA 2PUXA 1A0HA 1TB6L 2B5TA
chains in the Genus database with same CATH superfamily
1TQ7A 2A1DA 3HKIA 1Z8JA 3HK6A 4RKOA 1JOUA 3GISA 3BEIA 3E6PL 1TBRJ 2ODYA 3BEFA 3LU9A 3B9FL 1AVGL 3EDXA 1TBQJ 1JMOL 4DY7A 2PV9A 2PGQA 2PUXA 1A0HA 1TB6L 2B5TA
chains in the Genus database with same CATH topology
1TQ7A 2A1DA 3HKIA 1Z8JA 3HK6A 4RKOA 1JOUA 3GISA 3BEIA 3E6PL 1TBRJ 2ODYA 3BEFA 3LU9A 3B9FL 1AVGL 3EDXA 1TBQJ 1JMOL 4DY7A 2PV9A 2PGQA 2PUXA 1A0HA 1TB6L 2B5TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TQ7 A;  2A1D A;  3HKI A;  1Z8J A;  3HK6 A;  4RKO A;  1JOU A;  3GIS A;  3BEI A;  3E6P L;  1TBR J;  2ODY A;  3BEF A;  3LU9 A;  3B9F L;  1AVG L;  3EDX A;  1TBQ J;  1JMO L;  4DY7 A;  2PV9 A;  2PGQ A;  2PUX A;  1A0H A;  1TB6 L;  2B5T A; 
#chains in the Genus database with same CATH topology
 1TQ7 A;  2A1D A;  3HKI A;  1Z8J A;  3HK6 A;  4RKO A;  1JOU A;  3GIS A;  3BEI A;  3E6P L;  1TBR J;  2ODY A;  3BEF A;  3LU9 A;  3B9F L;  1AVG L;  3EDX A;  1TBQ J;  1JMO L;  4DY7 A;  2PV9 A;  2PGQ A;  2PUX A;  1A0H A;  1TB6 L;  2B5T A; 
#chains in the Genus database with same CATH homology
 1TQ7 A;  2A1D A;  3HKI A;  1Z8J A;  3HK6 A;  4RKO A;  1JOU A;  3GIS A;  3BEI A;  3E6P L;  1TBR J;  2ODY A;  3BEF A;  3LU9 A;  3B9F L;  1AVG L;  3EDX A;  1TBQ J;  1JMO L;  4DY7 A;  2PV9 A;  2PGQ A;  2PUX A;  1A0H A;  1TB6 L;  2B5T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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