3LU9A

Crystal structure of human thrombin mutant s195a in complex with the extracellular fragment of human par1
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
44
structure length
44
Chain Sequence
SEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Prothrombin
publication title Crystal structure of thrombin bound to the uncleaved extracellular fragment of PAR1.
pubmed doi rcsb
source organism Homo sapiens
total genus 3
structure length 44
sequence length 44
chains with identical sequence D
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2010-02-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 3lu9A00
1TB6L 3BEIA 3HKIA 1JOUA 2A1DA 2ODYA 2PGQA 3GISA 2B5TA 4DY7A 1JMOL 3E6PL 4RKOA 2PUXA 1Z8JA 1A0HA 1AVGL 3LU9A 3HK6A 1TBRJ 3B9FL 3BEFA 3EDXA 1TBQJ 1TQ7A 2PV9A
chains in the Genus database with same CATH superfamily
1TB6L 3BEIA 3HKIA 1JOUA 2A1DA 2ODYA 2PGQA 3GISA 2B5TA 4DY7A 1JMOL 3E6PL 4RKOA 2PUXA 1Z8JA 1A0HA 1AVGL 3LU9A 3HK6A 1TBRJ 3B9FL 3BEFA 3EDXA 1TBQJ 1TQ7A 2PV9A
chains in the Genus database with same CATH topology
1TB6L 3BEIA 3HKIA 1JOUA 2A1DA 2ODYA 2PGQA 3GISA 2B5TA 4DY7A 1JMOL 3E6PL 4RKOA 2PUXA 1Z8JA 1A0HA 1AVGL 3LU9A 3HK6A 1TBRJ 3B9FL 3BEFA 3EDXA 1TBQJ 1TQ7A 2PV9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TB6 L;  3BEI A;  3HKI A;  1JOU A;  2A1D A;  2ODY A;  2PGQ A;  3GIS A;  2B5T A;  4DY7 A;  1JMO L;  3E6P L;  4RKO A;  2PUX A;  1Z8J A;  1A0H A;  1AVG L;  3LU9 A;  3HK6 A;  1TBR J;  3B9F L;  3BEF A;  3EDX A;  1TBQ J;  1TQ7 A;  2PV9 A; 
#chains in the Genus database with same CATH topology
 1TB6 L;  3BEI A;  3HKI A;  1JOU A;  2A1D A;  2ODY A;  2PGQ A;  3GIS A;  2B5T A;  4DY7 A;  1JMO L;  3E6P L;  4RKO A;  2PUX A;  1Z8J A;  1A0H A;  1AVG L;  3LU9 A;  3HK6 A;  1TBR J;  3B9F L;  3BEF A;  3EDX A;  1TBQ J;  1TQ7 A;  2PV9 A; 
#chains in the Genus database with same CATH homology
 1TB6 L;  3BEI A;  3HKI A;  1JOU A;  2A1D A;  2ODY A;  2PGQ A;  3GIS A;  2B5T A;  4DY7 A;  1JMO L;  3E6P L;  4RKO A;  2PUX A;  1Z8J A;  1A0H A;  1AVG L;  3LU9 A;  3HK6 A;  1TBR J;  3B9F L;  3BEF A;  3EDX A;  1TBQ J;  1TQ7 A;  2PV9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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