3BBDA

M. jannaschii nep1 complexed with s-adenosyl-homocysteine
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
Knots found
sequence length
204
structure length
204
Chain Sequence
TYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYIHTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFIIGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
pubmed doi rcsb
molecule tags Transferase
source organism Methanocaldococcus jannaschii
molecule keywords Ribosome biogenesis protein NEP1-like
total genus 64
structure length 204
sequence length 204
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature
pdb deposition date 2007-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3bbdA00
1K3RA 4IG6A 2QMMA 4MCCA 5GMBA 2YY8A 4CNEA 2V3KA 4RG1A 1NS5A 3QUVA 2CX8A 5GMCA 1UAKA 4YVGA 4YQSA 4FAKA 4KGNA 1ZJRA 4E8BA 3AXZA 3KNUA 3L8UA 4CNDA 3IEFA 3BBHA 4YQJA 1UALA 4KDZA 4PZKA 4YQTA 1IPAA 3KTYA 1NXZA 4YQGA 4YQBA 4YPXA 4YQQA 3E5YA 1X7OA 4YQDA 4YPZA 4JAKA 3ONPA 5FAIA 4YQ3A 1V2XA 4L69A 1MXIA 4H3YA 2I6DA 4YQOA 3AI9X 3KW2A 1O6DA 3BBDA 3BBEA 4JALA 4X3LA 1P9PA 3NK6A 4CNFA 4YQNA 4J3CA 3N4JA 1VHKA 3AIAA 4YVHA 1UAJA 4MCDA 4YQCA 4YVKA 1VH0A 3O7BA 1X7PA 5GM8A 2O3AA 2Z0YA 5D9FA 4CNGA 2QWVA 4YQ2A 4YQAA 2HA8A 4YQ7A 2EGWA 4YQ8A 3ILKA 1J85A 4YQRA 4YQ4A 3NK7A 4YQ1A 3OINA 4YPWA 4YQ0A 3OIJA 3DCMX 1UAMA 4YVIA 4YVJA 4YPYA 1VHYA 4YQ6A 3GYQA 1TO0A 3OIIA 4YQLA 4XBOA 4MCBA 3IC6A 1OY5A 1V6ZA 1Z85A 3N4KA 4YQ5A 4YQIA 4H3ZA 4YQPA 2V3JA 5CO4A 4YQKA 2EGVA 4X3MA 1GZ0A 4YQ9A 3KY7A
chains in the Genus database with same CATH superfamily
1K3RA 4IG6A 2QMMA 4MCCA 5GMBA 2YY8A 4CNEA 2V3KA 4RG1A 1NS5A 3QUVA 2CX8A 5GMCA 1UAKA 4YVGA 4YQSA 4FAKA 4KGNA 1ZJRA 4E8BA 3AXZA 3KNUA 3L8UA 4CNDA 4JWGA 3IEFA 3BBHA 4JWHA 4YQJA 1UALA 4KDZA 4PZKA 4YQTA 1IPAA 3KTYA 1NXZA 4YQGA 4YQBA 4YPXA 4YQQA 3E5YA 1X7OA 4YQDA 4YPZA 4JAKA 3ONPA 5FAIA 4YQ3A 1V2XA 4L69A 1MXIA 4H3YA 2I6DA 4YQOA 3AI9X 3KW2A 1O6DA 3BBDA 3BBEA 4JALA 4X3LA 1P9PA 3NK6A 4JWJA 4CNFA 4YQNA 4J3CA 3N4JA 1VHKA 3AIAA 4YVHA 1UAJA 4MCDA 4YQCA 4YVKA 1VH0A 3O7BA 1X7PA 5GM8A 2O3AA 2Z0YA 5D9FA 4CNGA 2QWVA 4YQ2A 4YQAA 4FMWA 2HA8A 4YQ7A 2EGWA 4YQ8A 3ILKA 1J85A 4YQRA 4YQ4A 3NK7A 4YQ1A 3OINA 4YPWA 4YQ0A 3OIJA 3DCMX 1UAMA 4YVIA 4YVJA 4YPYA 1VHYA 4YQ6A 3GYQA 1TO0A 3OIIA 4YQLA 4XBOA 4MCBA 3IC6A 1OY5A 1V6ZA 1Z85A 3N4KA 4YQ5A 4YQIA 4H3ZA 4YQPA 2V3JA 5CO4A 4YQKA 2EGVA 4X3MA 1GZ0A 4YQ9A 3KY7A 4JWFA
chains in the Genus database with same CATH topology
1K3RA 4IG6A 2QMMA 4MCCA 5GMBA 2YY8A 4CNEA 2V3KA 4RG1A 1NS5A 3QUVA 2CX8A 5GMCA 1UAKA 4YVGA 4YQSA 4FAKA 4KGNA 1ZJRA 4E8BA 3AXZA 3KNUA 3L8UA 4CNDA 4JWGA 3IEFA 3BBHA 4JWHA 4YQJA 1UALA 4KDZA 4PZKA 4YQTA 1IPAA 3KTYA 1NXZA 4YQGA 4YQBA 4YPXA 4YQQA 3E5YA 1X7OA 4YQDA 4YPZA 4JAKA 3ONPA 5FAIA 4YQ3A 1V2XA 4L69A 1MXIA 4H3YA 2I6DA 4YQOA 3AI9X 3KW2A 1O6DA 3BBDA 3BBEA 4JALA 4X3LA 1P9PA 3NK6A 4JWJA 4CNFA 4YQNA 4J3CA 3N4JA 1VHKA 3AIAA 4YVHA 1UAJA 4MCDA 4YQCA 4YVKA 1VH0A 3O7BA 1X7PA 5GM8A 2O3AA 2Z0YA 5D9FA 4CNGA 2QWVA 4YQ2A 4YQAA 4FMWA 2HA8A 4YQ7A 2EGWA 4YQ8A 3ILKA 1J85A 4YQRA 4YQ4A 3NK7A 4YQ1A 3OINA 4YPWA 4YQ0A 3OIJA 3DCMX 1UAMA 4YVIA 4YVJA 4YPYA 1VHYA 4YQ6A 3GYQA 1TO0A 3OIIA 4YQLA 4XBOA 4MCBA 3IC6A 1OY5A 1V6ZA 1Z85A 3N4KA 4YQ5A 4YQIA 4H3ZA 4YQPA 2V3JA 5CO4A 4YQKA 2EGVA 4X3MA 1GZ0A 4YQ9A 3KY7A 4JWFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K3R A;  4IG6 A;  2QMM A;  4MCC A;  5GMB A;  2YY8 A;  4CNE A;  2V3K A;  4RG1 A;  1NS5 A;  3QUV A;  2CX8 A;  5GMC A;  1UAK A;  4YVG A;  4YQS A;  4FAK A;  4KGN A;  1ZJR A;  4E8B A;  3AXZ A;  3KNU A;  3L8U A;  4CND A;  3IEF A;  3BBH A;  4YQJ A;  1UAL A;  4KDZ A;  4PZK A;  4YQT A;  1IPA A;  3KTY A;  1NXZ A;  4YQG A;  4YQB A;  4YPX A;  4YQQ A;  3E5Y A;  1X7O A;  4YQD A;  4YPZ A;  4JAK A;  3ONP A;  5FAI A;  4YQ3 A;  1V2X A;  4L69 A;  1MXI A;  4H3Y A;  2I6D A;  4YQO A;  3AI9 X;  3KW2 A;  1O6D A;  3BBD A;  3BBE A;  4JAL A;  4X3L A;  1P9P A;  3NK6 A;  4CNF A;  4YQN A;  4J3C A;  3N4J A;  1VHK A;  3AIA A;  4YVH A;  1UAJ A;  4MCD A;  4YQC A;  4YVK A;  1VH0 A;  3O7B A;  1X7P A;  5GM8 A;  2O3A A;  2Z0Y A;  5D9F A;  4CNG A;  2QWV A;  4YQ2 A;  4YQA A;  2HA8 A;  4YQ7 A;  2EGW A;  4YQ8 A;  3ILK A;  1J85 A;  4YQR A;  4YQ4 A;  3NK7 A;  4YQ1 A;  3OIN A;  4YPW A;  4YQ0 A;  3OIJ A;  3DCM X;  1UAM A;  4YVI A;  4YVJ A;  4YPY A;  1VHY A;  4YQ6 A;  3GYQ A;  1TO0 A;  3OII A;  4YQL A;  4XBO A;  4MCB A;  3IC6 A;  1OY5 A;  1V6Z A;  1Z85 A;  3N4K A;  4YQ5 A;  4YQI A;  4H3Z A;  4YQP A;  2V3J A;  5CO4 A;  4YQK A;  2EGV A;  4X3M A;  1GZ0 A;  4YQ9 A;  3KY7 A; 
#chains in the Genus database with same CATH topology
 1K3R A;  4IG6 A;  2QMM A;  4MCC A;  5GMB A;  2YY8 A;  4CNE A;  2V3K A;  4RG1 A;  1NS5 A;  3QUV A;  2CX8 A;  5GMC A;  1UAK A;  4YVG A;  4YQS A;  4FAK A;  4KGN A;  1ZJR A;  4E8B A;  3AXZ A;  3KNU A;  3L8U A;  4CND A;  4JWG A;  3IEF A;  3BBH A;  4JWH A;  4YQJ A;  1UAL A;  4KDZ A;  4PZK A;  4YQT A;  1IPA A;  3KTY A;  1NXZ A;  4YQG A;  4YQB A;  4YPX A;  4YQQ A;  3E5Y A;  1X7O A;  4YQD A;  4YPZ A;  4JAK A;  3ONP A;  5FAI A;  4YQ3 A;  1V2X A;  4L69 A;  1MXI A;  4H3Y A;  2I6D A;  4YQO A;  3AI9 X;  3KW2 A;  1O6D A;  3BBD A;  3BBE A;  4JAL A;  4X3L A;  1P9P A;  3NK6 A;  4JWJ A;  4CNF A;  4YQN A;  4J3C A;  3N4J A;  1VHK A;  3AIA A;  4YVH A;  1UAJ A;  4MCD A;  4YQC A;  4YVK A;  1VH0 A;  3O7B A;  1X7P A;  5GM8 A;  2O3A A;  2Z0Y A;  5D9F A;  4CNG A;  2QWV A;  4YQ2 A;  4YQA A;  4FMW A;  2HA8 A;  4YQ7 A;  2EGW A;  4YQ8 A;  3ILK A;  1J85 A;  4YQR A;  4YQ4 A;  3NK7 A;  4YQ1 A;  3OIN A;  4YPW A;  4YQ0 A;  3OIJ A;  3DCM X;  1UAM A;  4YVI A;  4YVJ A;  4YPY A;  1VHY A;  4YQ6 A;  3GYQ A;  1TO0 A;  3OII A;  4YQL A;  4XBO A;  4MCB A;  3IC6 A;  1OY5 A;  1V6Z A;  1Z85 A;  3N4K A;  4YQ5 A;  4YQI A;  4H3Z A;  4YQP A;  2V3J A;  5CO4 A;  4YQK A;  2EGV A;  4X3M A;  1GZ0 A;  4YQ9 A;  3KY7 A;  4JWF A; 
#chains in the Genus database with same CATH homology
 1K3R A;  4IG6 A;  2QMM A;  4MCC A;  5GMB A;  2YY8 A;  4CNE A;  2V3K A;  4RG1 A;  1NS5 A;  3QUV A;  2CX8 A;  5GMC A;  1UAK A;  4YVG A;  4YQS A;  4FAK A;  4KGN A;  1ZJR A;  4E8B A;  3AXZ A;  3KNU A;  3L8U A;  4CND A;  4JWG A;  3IEF A;  3BBH A;  4JWH A;  4YQJ A;  1UAL A;  4KDZ A;  4PZK A;  4YQT A;  1IPA A;  3KTY A;  1NXZ A;  4YQG A;  4YQB A;  4YPX A;  4YQQ A;  3E5Y A;  1X7O A;  4YQD A;  4YPZ A;  4JAK A;  3ONP A;  5FAI A;  4YQ3 A;  1V2X A;  4L69 A;  1MXI A;  4H3Y A;  2I6D A;  4YQO A;  3AI9 X;  3KW2 A;  1O6D A;  3BBD A;  3BBE A;  4JAL A;  4X3L A;  1P9P A;  3NK6 A;  4JWJ A;  4CNF A;  4YQN A;  4J3C A;  3N4J A;  1VHK A;  3AIA A;  4YVH A;  1UAJ A;  4MCD A;  4YQC A;  4YVK A;  1VH0 A;  3O7B A;  1X7P A;  5GM8 A;  2O3A A;  2Z0Y A;  5D9F A;  4CNG A;  2QWV A;  4YQ2 A;  4YQA A;  4FMW A;  2HA8 A;  4YQ7 A;  2EGW A;  4YQ8 A;  3ILK A;  1J85 A;  4YQR A;  4YQ4 A;  3NK7 A;  4YQ1 A;  3OIN A;  4YPW A;  4YQ0 A;  3OIJ A;  3DCM X;  1UAM A;  4YVI A;  4YVJ A;  4YPY A;  1VHY A;  4YQ6 A;  3GYQ A;  1TO0 A;  3OII A;  4YQL A;  4XBO A;  4MCB A;  3IC6 A;  1OY5 A;  1V6Z A;  1Z85 A;  3N4K A;  4YQ5 A;  4YQI A;  4H3Z A;  4YQP A;  2V3J A;  5CO4 A;  4YQK A;  2EGV A;  4X3M A;  1GZ0 A;  4YQ9 A;  3KY7 A;  4JWF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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