3BBHA

M. jannaschii nep1 complexed with sinefungin
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
Knots found
sequence length
204
structure length
204
Chain Sequence
TYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYIHTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFIIGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
pubmed doi rcsb
molecule tags Transferase
source organism Methanocaldococcus jannaschii
molecule keywords Ribosome biogenesis protein NEP1-like
total genus 69
structure length 204
sequence length 204
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature
pdb deposition date 2007-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3bbhA00
1NXZA 3OIIA 3OINA 5GM8A 4YPZA 5GMBA 4CNDA 1UAJA 4YQKA 3O7BA 4YQSA 4YQJA 1IPAA 4YQ7A 2EGVA 4YQCA 1UALA 4H3ZA 4JALA 3L8UA 4YQPA 5CO4A 2CX8A 4CNFA 2O3AA 3BBHA 4YQ3A 1VH0A 3NK7A 4PZKA 5GMCA 2QMMA 3GYQA 3N4JA 4YVHA 4YPYA 4YPXA 3E5YA 2QWVA 3KTYA 4MCCA 4YQ0A 4YPWA 1X7PA 4CNEA 2V3KA 1V6ZA 4MCBA 1J85A 3ONPA 3AIAA 4YQTA 3KW2A 4X3MA 1VHKA 5D9FA 4RG1A 1K3RA 4YQBA 1TO0A 4L69A 3ILKA 3BBDA 4FAKA 4YQ1A 1X7OA 1P9PA 2I6DA 3N4KA 1MXIA 1UAKA 4YQ6A 3NK6A 1UAMA 4YQIA 4IG6A 4YVJA 3IEFA 1O6DA 3AXZA 2EGWA 3KNUA 4YQQA 1GZ0A 2V3JA 1ZJRA 4XBOA 4E8BA 4YQLA 4YVKA 4YQ5A 2YY8A 4YVIA 4YQAA 1NS5A 3BBEA 4YQOA 1VHYA 4YQ2A 3IC6A 1V2XA 4KDZA 4YQRA 4YQ8A 1Z85A 2Z0YA 4J3CA 5FAIA 4YQDA 3DCMX 2HA8A 4YQ4A 4CNGA 4MCDA 4KGNA 4YQ9A 4H3YA 4YQNA 3OIJA 4YVGA 3AI9X 3QUVA 4JAKA 1OY5A 4X3LA 4YQGA 3KY7A
chains in the Genus database with same CATH superfamily
1NXZA 3OIIA 3OINA 5GM8A 4YPZA 5GMBA 4CNDA 1UAJA 4YQKA 3O7BA 4YQSA 4YQJA 1IPAA 4YQ7A 2EGVA 4YQCA 1UALA 4H3ZA 4JALA 3L8UA 4YQPA 5CO4A 2CX8A 4CNFA 2O3AA 4JWFA 3BBHA 4YQ3A 1VH0A 3NK7A 4PZKA 5GMCA 2QMMA 3GYQA 4FMWA 3N4JA 4YVHA 4YPYA 4YPXA 3E5YA 2QWVA 3KTYA 4MCCA 4YQ0A 4YPWA 1X7PA 4CNEA 2V3KA 1V6ZA 4MCBA 1J85A 3ONPA 3AIAA 4YQTA 3KW2A 4X3MA 1VHKA 5D9FA 1K3RA 4RG1A 4YQBA 1TO0A 4L69A 3ILKA 3BBDA 4JWJA 4FAKA 4YQ1A 1X7OA 1P9PA 2I6DA 3N4KA 1MXIA 1UAKA 4YQ6A 3NK6A 1UAMA 4YQIA 4IG6A 4YVJA 3IEFA 1O6DA 3AXZA 2EGWA 3KNUA 4YQQA 1GZ0A 2V3JA 1ZJRA 4XBOA 4E8BA 4YQLA 4YVKA 4YQ5A 2YY8A 4YVIA 4YQAA 1NS5A 3BBEA 4YQOA 1VHYA 4YQ2A 3IC6A 1V2XA 4JWGA 4KDZA 4YQRA 4JWHA 4YQ8A 1Z85A 2Z0YA 4J3CA 5FAIA 4YQDA 3DCMX 2HA8A 4YQ4A 4CNGA 4MCDA 4KGNA 4YQ9A 4H3YA 4YQNA 3OIJA 4YVGA 3AI9X 3QUVA 4JAKA 1OY5A 4X3LA 4YQGA 3KY7A
chains in the Genus database with same CATH topology
1NXZA 3OIIA 3OINA 5GM8A 4YPZA 5GMBA 4CNDA 1UAJA 4YQKA 3O7BA 4YQSA 4YQJA 1IPAA 4YQ7A 2EGVA 4YQCA 1UALA 4H3ZA 4JALA 3L8UA 4YQPA 5CO4A 2CX8A 4CNFA 2O3AA 4JWFA 3BBHA 4YQ3A 1VH0A 3NK7A 4PZKA 5GMCA 2QMMA 3GYQA 4FMWA 3N4JA 4YVHA 4YPYA 4YPXA 3E5YA 2QWVA 3KTYA 4MCCA 4YQ0A 4YPWA 1X7PA 4CNEA 2V3KA 1V6ZA 4MCBA 1J85A 3ONPA 3AIAA 4YQTA 3KW2A 4X3MA 1VHKA 5D9FA 1K3RA 4RG1A 4YQBA 1TO0A 4L69A 3ILKA 3BBDA 4JWJA 4FAKA 4YQ1A 1X7OA 1P9PA 2I6DA 3N4KA 1MXIA 1UAKA 4YQ6A 3NK6A 1UAMA 4YQIA 4IG6A 4YVJA 3IEFA 1O6DA 3AXZA 2EGWA 3KNUA 4YQQA 1GZ0A 2V3JA 1ZJRA 4XBOA 4E8BA 4YQLA 4YVKA 4YQ5A 2YY8A 4YVIA 4YQAA 1NS5A 3BBEA 4YQOA 1VHYA 4YQ2A 3IC6A 1V2XA 4JWGA 4KDZA 4YQRA 4JWHA 4YQ8A 1Z85A 2Z0YA 4J3CA 5FAIA 4YQDA 3DCMX 2HA8A 4YQ4A 4CNGA 4MCDA 4KGNA 4YQ9A 4H3YA 4YQNA 3OIJA 4YVGA 3AI9X 3QUVA 4JAKA 1OY5A 4X3LA 4YQGA 3KY7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NXZ A;  3OII A;  3OIN A;  5GM8 A;  4YPZ A;  5GMB A;  4CND A;  1UAJ A;  4YQK A;  3O7B A;  4YQS A;  4YQJ A;  1IPA A;  4YQ7 A;  2EGV A;  4YQC A;  1UAL A;  4H3Z A;  4JAL A;  3L8U A;  4YQP A;  5CO4 A;  2CX8 A;  4CNF A;  2O3A A;  3BBH A;  4YQ3 A;  1VH0 A;  3NK7 A;  4PZK A;  5GMC A;  2QMM A;  3GYQ A;  3N4J A;  4YVH A;  4YPY A;  4YPX A;  3E5Y A;  2QWV A;  3KTY A;  4MCC A;  4YQ0 A;  4YPW A;  1X7P A;  4CNE A;  2V3K A;  1V6Z A;  4MCB A;  1J85 A;  3ONP A;  3AIA A;  4YQT A;  3KW2 A;  4X3M A;  1VHK A;  5D9F A;  4RG1 A;  1K3R A;  4YQB A;  1TO0 A;  4L69 A;  3ILK A;  3BBD A;  4FAK A;  4YQ1 A;  1X7O A;  1P9P A;  2I6D A;  3N4K A;  1MXI A;  1UAK A;  4YQ6 A;  3NK6 A;  1UAM A;  4YQI A;  4IG6 A;  4YVJ A;  3IEF A;  1O6D A;  3AXZ A;  2EGW A;  3KNU A;  4YQQ A;  1GZ0 A;  2V3J A;  1ZJR A;  4XBO A;  4E8B A;  4YQL A;  4YVK A;  4YQ5 A;  2YY8 A;  4YVI A;  4YQA A;  1NS5 A;  3BBE A;  4YQO A;  1VHY A;  4YQ2 A;  3IC6 A;  1V2X A;  4KDZ A;  4YQR A;  4YQ8 A;  1Z85 A;  2Z0Y A;  4J3C A;  5FAI A;  4YQD A;  3DCM X;  2HA8 A;  4YQ4 A;  4CNG A;  4MCD A;  4KGN A;  4YQ9 A;  4H3Y A;  4YQN A;  3OIJ A;  4YVG A;  3AI9 X;  3QUV A;  4JAK A;  1OY5 A;  4X3L A;  4YQG A;  3KY7 A; 
#chains in the Genus database with same CATH topology
 1NXZ A;  3OII A;  3OIN A;  5GM8 A;  4YPZ A;  5GMB A;  4CND A;  1UAJ A;  4YQK A;  3O7B A;  4YQS A;  4YQJ A;  1IPA A;  4YQ7 A;  2EGV A;  4YQC A;  1UAL A;  4H3Z A;  4JAL A;  3L8U A;  4YQP A;  5CO4 A;  2CX8 A;  4CNF A;  2O3A A;  4JWF A;  3BBH A;  4YQ3 A;  1VH0 A;  3NK7 A;  4PZK A;  5GMC A;  2QMM A;  3GYQ A;  4FMW A;  3N4J A;  4YVH A;  4YPY A;  4YPX A;  3E5Y A;  2QWV A;  3KTY A;  4MCC A;  4YQ0 A;  4YPW A;  1X7P A;  4CNE A;  2V3K A;  1V6Z A;  4MCB A;  1J85 A;  3ONP A;  3AIA A;  4YQT A;  3KW2 A;  4X3M A;  1VHK A;  5D9F A;  1K3R A;  4RG1 A;  4YQB A;  1TO0 A;  4L69 A;  3ILK A;  3BBD A;  4JWJ A;  4FAK A;  4YQ1 A;  1X7O A;  1P9P A;  2I6D A;  3N4K A;  1MXI A;  1UAK A;  4YQ6 A;  3NK6 A;  1UAM A;  4YQI A;  4IG6 A;  4YVJ A;  3IEF A;  1O6D A;  3AXZ A;  2EGW A;  3KNU A;  4YQQ A;  1GZ0 A;  2V3J A;  1ZJR A;  4XBO A;  4E8B A;  4YQL A;  4YVK A;  4YQ5 A;  2YY8 A;  4YVI A;  4YQA A;  1NS5 A;  3BBE A;  4YQO A;  1VHY A;  4YQ2 A;  3IC6 A;  1V2X A;  4JWG A;  4KDZ A;  4YQR A;  4JWH A;  4YQ8 A;  1Z85 A;  2Z0Y A;  4J3C A;  5FAI A;  4YQD A;  3DCM X;  2HA8 A;  4YQ4 A;  4CNG A;  4MCD A;  4KGN A;  4YQ9 A;  4H3Y A;  4YQN A;  3OIJ A;  4YVG A;  3AI9 X;  3QUV A;  4JAK A;  1OY5 A;  4X3L A;  4YQG A;  3KY7 A; 
#chains in the Genus database with same CATH homology
 1NXZ A;  3OII A;  3OIN A;  5GM8 A;  4YPZ A;  5GMB A;  4CND A;  1UAJ A;  4YQK A;  3O7B A;  4YQS A;  4YQJ A;  1IPA A;  4YQ7 A;  2EGV A;  4YQC A;  1UAL A;  4H3Z A;  4JAL A;  3L8U A;  4YQP A;  5CO4 A;  2CX8 A;  4CNF A;  2O3A A;  4JWF A;  3BBH A;  4YQ3 A;  1VH0 A;  3NK7 A;  4PZK A;  5GMC A;  2QMM A;  3GYQ A;  4FMW A;  3N4J A;  4YVH A;  4YPY A;  4YPX A;  3E5Y A;  2QWV A;  3KTY A;  4MCC A;  4YQ0 A;  4YPW A;  1X7P A;  4CNE A;  2V3K A;  1V6Z A;  4MCB A;  1J85 A;  3ONP A;  3AIA A;  4YQT A;  3KW2 A;  4X3M A;  1VHK A;  5D9F A;  1K3R A;  4RG1 A;  4YQB A;  1TO0 A;  4L69 A;  3ILK A;  3BBD A;  4JWJ A;  4FAK A;  4YQ1 A;  1X7O A;  1P9P A;  2I6D A;  3N4K A;  1MXI A;  1UAK A;  4YQ6 A;  3NK6 A;  1UAM A;  4YQI A;  4IG6 A;  4YVJ A;  3IEF A;  1O6D A;  3AXZ A;  2EGW A;  3KNU A;  4YQQ A;  1GZ0 A;  2V3J A;  1ZJR A;  4XBO A;  4E8B A;  4YQL A;  4YVK A;  4YQ5 A;  2YY8 A;  4YVI A;  4YQA A;  1NS5 A;  3BBE A;  4YQO A;  1VHY A;  4YQ2 A;  3IC6 A;  1V2X A;  4JWG A;  4KDZ A;  4YQR A;  4JWH A;  4YQ8 A;  1Z85 A;  2Z0Y A;  4J3C A;  5FAI A;  4YQD A;  3DCM X;  2HA8 A;  4YQ4 A;  4CNG A;  4MCD A;  4KGN A;  4YQ9 A;  4H3Y A;  4YQN A;  3OIJ A;  4YVG A;  3AI9 X;  3QUV A;  4JAK A;  1OY5 A;  4X3L A;  4YQG A;  3KY7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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