3O7BA

Crystal structure of archaeoglobus fulgidus nep1 bound to s-adenosylhomocysteine
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
Knots found
sequence length
216
structure length
216
Chain Sequence
MGSAFVFLEASLELIPQKIRGHPAVRADAIRRGKRPEKILLDDSKHHTAMKSLEFREKRGRPDIVHQCLLLLLDSPLRDFEVYVHTLNGEIIWVNRETRLPRNYNRFVGLMEKLFEERRITAGDTTLIEFKDVGLRDIVRGRDVLLFREKGGRFEFSELLDGDVAVCIGAFPHGDFFEETLRELGEFKEVSLGTESYTSLYVTSRVLCEYERVRAH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule tags Transferase
source organism Archaeoglobus fulgidus
molecule keywords Ribosome biogenesis Nep1 RNA methyltransferase
total genus 75
structure length 216
sequence length 216
other databases KnotProt 2.0: K +31
ec nomenclature
pdb deposition date 2010-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3o7bA00
5GMBA 2YY8A 1J85A 3OINA 3QUVA 4PZKA 4X3MA 1UALA 4YQ7A 4YQ6A 3KW2A 1MXIA 4CNEA 1IPAA 4L69A 4YPXA 2V3JA 3NK7A 1VHKA 5D9FA 4YQQA 4CNDA 4E8BA 4H3ZA 1ZJRA 4YQSA 4YQ9A 1Z85A 4YQDA 4YVJA 2EGVA 5GM8A 4YPZA 1NXZA 3GYQA 4YQCA 4YQIA 3N4KA 3E5YA 1UAJA 3ONPA 3BBHA 4YQPA 2HA8A 4MCBA 4JAKA 3ILKA 1VHYA 3OIJA 4YVKA 4YQBA 2CX8A 3AI9X 4YQLA 4YQ5A 3AXZA 1NS5A 4YQRA 1K3RA 4KGNA 3AIAA 2EGWA 3IEFA 3BBDA 4YQ4A 4YQ1A 4YQOA 2V3KA 4YQ0A 3KY7A 4YPYA 4YQNA 3N4JA 1V6ZA 2Z0YA 1P9PA 2I6DA 3O7BA 4YQ3A 4CNGA 1VH0A 4CNFA 4J3CA 1OY5A 1GZ0A 1UAKA 2QWVA 4YQTA 4FAKA 4YPWA 4RG1A 4YVIA 5CO4A 4JALA 4MCDA 4YQGA 3DCMX 3KTYA 4XBOA 1O6DA 4IG6A 4YVHA 3IC6A 4MCCA 5FAIA 3KNUA 1TO0A 3L8UA 5GMCA 4KDZA 2O3AA 4YQJA 1X7OA 1V2XA 4YQKA 2QMMA 1X7PA 3NK6A 4H3YA 4YQ8A 4YVGA 4YQ2A 1UAMA 3BBEA 4X3LA 4YQAA 3OIIA
chains in the Genus database with same CATH superfamily
5GMBA 2YY8A 1J85A 3OINA 3QUVA 4PZKA 4X3MA 1UALA 4YQ7A 4YQ6A 3KW2A 1MXIA 4CNEA 1IPAA 4L69A 4YPXA 2V3JA 3NK7A 1VHKA 5D9FA 4YQQA 4CNDA 4E8BA 4H3ZA 1ZJRA 4YQSA 4YQ9A 1Z85A 4YQDA 4YVJA 2EGVA 5GM8A 4YPZA 1NXZA 3GYQA 4YQCA 4JWHA 4JWGA 4YQIA 3N4KA 3E5YA 1UAJA 3ONPA 3BBHA 4YQPA 2HA8A 4MCBA 4JAKA 3ILKA 1VHYA 3OIJA 4YVKA 4YQBA 2CX8A 3AI9X 4YQLA 4YQ5A 3AXZA 1NS5A 4JWFA 4YQRA 1K3RA 4KGNA 3AIAA 2EGWA 3IEFA 3BBDA 4YQ4A 4YQ1A 4YQOA 2V3KA 4YQ0A 3KY7A 4YPYA 4YQNA 3N4JA 1V6ZA 2Z0YA 4FMWA 1P9PA 2I6DA 3O7BA 4YQ3A 4CNGA 1VH0A 4CNFA 4J3CA 1OY5A 1GZ0A 1UAKA 2QWVA 4YQTA 4FAKA 4YPWA 4RG1A 4YVIA 4JWJA 5CO4A 4JALA 4MCDA 4YQGA 3DCMX 3KTYA 4XBOA 1O6DA 4IG6A 4YVHA 3IC6A 4MCCA 5FAIA 3KNUA 1TO0A 3L8UA 5GMCA 4KDZA 2O3AA 4YQJA 1X7OA 1V2XA 4YQKA 2QMMA 1X7PA 3NK6A 4H3YA 4YQ8A 4YVGA 4YQ2A 1UAMA 3BBEA 4X3LA 4YQAA 3OIIA
chains in the Genus database with same CATH topology
5GMBA 2YY8A 1J85A 3OINA 3QUVA 4PZKA 4X3MA 1UALA 4YQ7A 4YQ6A 3KW2A 1MXIA 4CNEA 1IPAA 4L69A 4YPXA 2V3JA 3NK7A 1VHKA 5D9FA 4YQQA 4CNDA 4E8BA 4H3ZA 1ZJRA 4YQSA 4YQ9A 1Z85A 4YQDA 4YVJA 2EGVA 5GM8A 4YPZA 1NXZA 3GYQA 4YQCA 4JWHA 4JWGA 4YQIA 3N4KA 3E5YA 1UAJA 3ONPA 3BBHA 4YQPA 2HA8A 4MCBA 4JAKA 3ILKA 1VHYA 3OIJA 4YVKA 4YQBA 2CX8A 3AI9X 4YQLA 4YQ5A 3AXZA 1NS5A 4JWFA 4YQRA 1K3RA 4KGNA 3AIAA 2EGWA 3IEFA 3BBDA 4YQ4A 4YQ1A 4YQOA 2V3KA 4YQ0A 3KY7A 4YPYA 4YQNA 3N4JA 1V6ZA 2Z0YA 4FMWA 1P9PA 2I6DA 3O7BA 4YQ3A 4CNGA 1VH0A 4CNFA 4J3CA 1OY5A 1GZ0A 1UAKA 2QWVA 4YQTA 4FAKA 4YPWA 4RG1A 4YVIA 4JWJA 5CO4A 4JALA 4MCDA 4YQGA 3DCMX 3KTYA 4XBOA 1O6DA 4IG6A 4YVHA 3IC6A 4MCCA 5FAIA 3KNUA 1TO0A 3L8UA 5GMCA 4KDZA 2O3AA 4YQJA 1X7OA 1V2XA 4YQKA 2QMMA 1X7PA 3NK6A 4H3YA 4YQ8A 4YVGA 4YQ2A 1UAMA 3BBEA 4X3LA 4YQAA 3OIIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GMB A;  2YY8 A;  1J85 A;  3OIN A;  3QUV A;  4PZK A;  4X3M A;  1UAL A;  4YQ7 A;  4YQ6 A;  3KW2 A;  1MXI A;  4CNE A;  1IPA A;  4L69 A;  4YPX A;  2V3J A;  3NK7 A;  1VHK A;  5D9F A;  4YQQ A;  4CND A;  4E8B A;  4H3Z A;  1ZJR A;  4YQS A;  4YQ9 A;  1Z85 A;  4YQD A;  4YVJ A;  2EGV A;  5GM8 A;  4YPZ A;  1NXZ A;  3GYQ A;  4YQC A;  4YQI A;  3N4K A;  3E5Y A;  1UAJ A;  3ONP A;  3BBH A;  4YQP A;  2HA8 A;  4MCB A;  4JAK A;  3ILK A;  1VHY A;  3OIJ A;  4YVK A;  4YQB A;  2CX8 A;  3AI9 X;  4YQL A;  4YQ5 A;  3AXZ A;  1NS5 A;  4YQR A;  1K3R A;  4KGN A;  3AIA A;  2EGW A;  3IEF A;  3BBD A;  4YQ4 A;  4YQ1 A;  4YQO A;  2V3K A;  4YQ0 A;  3KY7 A;  4YPY A;  4YQN A;  3N4J A;  1V6Z A;  2Z0Y A;  1P9P A;  2I6D A;  3O7B A;  4YQ3 A;  4CNG A;  1VH0 A;  4CNF A;  4J3C A;  1OY5 A;  1GZ0 A;  1UAK A;  2QWV A;  4YQT A;  4FAK A;  4YPW A;  4RG1 A;  4YVI A;  5CO4 A;  4JAL A;  4MCD A;  4YQG A;  3DCM X;  3KTY A;  4XBO A;  1O6D A;  4IG6 A;  4YVH A;  3IC6 A;  4MCC A;  5FAI A;  3KNU A;  1TO0 A;  3L8U A;  5GMC A;  4KDZ A;  2O3A A;  4YQJ A;  1X7O A;  1V2X A;  4YQK A;  2QMM A;  1X7P A;  3NK6 A;  4H3Y A;  4YQ8 A;  4YVG A;  4YQ2 A;  1UAM A;  3BBE A;  4X3L A;  4YQA A;  3OII A; 
#chains in the Genus database with same CATH topology
 5GMB A;  2YY8 A;  1J85 A;  3OIN A;  3QUV A;  4PZK A;  4X3M A;  1UAL A;  4YQ7 A;  4YQ6 A;  3KW2 A;  1MXI A;  4CNE A;  1IPA A;  4L69 A;  4YPX A;  2V3J A;  3NK7 A;  1VHK A;  5D9F A;  4YQQ A;  4CND A;  4E8B A;  4H3Z A;  1ZJR A;  4YQS A;  4YQ9 A;  1Z85 A;  4YQD A;  4YVJ A;  2EGV A;  5GM8 A;  4YPZ A;  1NXZ A;  3GYQ A;  4YQC A;  4JWH A;  4JWG A;  4YQI A;  3N4K A;  3E5Y A;  1UAJ A;  3ONP A;  3BBH A;  4YQP A;  2HA8 A;  4MCB A;  4JAK A;  3ILK A;  1VHY A;  3OIJ A;  4YVK A;  4YQB A;  2CX8 A;  3AI9 X;  4YQL A;  4YQ5 A;  3AXZ A;  1NS5 A;  4JWF A;  4YQR A;  1K3R A;  4KGN A;  3AIA A;  2EGW A;  3IEF A;  3BBD A;  4YQ4 A;  4YQ1 A;  4YQO A;  2V3K A;  4YQ0 A;  3KY7 A;  4YPY A;  4YQN A;  3N4J A;  1V6Z A;  2Z0Y A;  4FMW A;  1P9P A;  2I6D A;  3O7B A;  4YQ3 A;  4CNG A;  1VH0 A;  4CNF A;  4J3C A;  1OY5 A;  1GZ0 A;  1UAK A;  2QWV A;  4YQT A;  4FAK A;  4YPW A;  4RG1 A;  4YVI A;  4JWJ A;  5CO4 A;  4JAL A;  4MCD A;  4YQG A;  3DCM X;  3KTY A;  4XBO A;  1O6D A;  4IG6 A;  4YVH A;  3IC6 A;  4MCC A;  5FAI A;  3KNU A;  1TO0 A;  3L8U A;  5GMC A;  4KDZ A;  2O3A A;  4YQJ A;  1X7O A;  1V2X A;  4YQK A;  2QMM A;  1X7P A;  3NK6 A;  4H3Y A;  4YQ8 A;  4YVG A;  4YQ2 A;  1UAM A;  3BBE A;  4X3L A;  4YQA A;  3OII A; 
#chains in the Genus database with same CATH homology
 5GMB A;  2YY8 A;  1J85 A;  3OIN A;  3QUV A;  4PZK A;  4X3M A;  1UAL A;  4YQ7 A;  4YQ6 A;  3KW2 A;  1MXI A;  4CNE A;  1IPA A;  4L69 A;  4YPX A;  2V3J A;  3NK7 A;  1VHK A;  5D9F A;  4YQQ A;  4CND A;  4E8B A;  4H3Z A;  1ZJR A;  4YQS A;  4YQ9 A;  1Z85 A;  4YQD A;  4YVJ A;  2EGV A;  5GM8 A;  4YPZ A;  1NXZ A;  3GYQ A;  4YQC A;  4JWH A;  4JWG A;  4YQI A;  3N4K A;  3E5Y A;  1UAJ A;  3ONP A;  3BBH A;  4YQP A;  2HA8 A;  4MCB A;  4JAK A;  3ILK A;  1VHY A;  3OIJ A;  4YVK A;  4YQB A;  2CX8 A;  3AI9 X;  4YQL A;  4YQ5 A;  3AXZ A;  1NS5 A;  4JWF A;  4YQR A;  1K3R A;  4KGN A;  3AIA A;  2EGW A;  3IEF A;  3BBD A;  4YQ4 A;  4YQ1 A;  4YQO A;  2V3K A;  4YQ0 A;  3KY7 A;  4YPY A;  4YQN A;  3N4J A;  1V6Z A;  2Z0Y A;  4FMW A;  1P9P A;  2I6D A;  3O7B A;  4YQ3 A;  4CNG A;  1VH0 A;  4CNF A;  4J3C A;  1OY5 A;  1GZ0 A;  1UAK A;  2QWV A;  4YQT A;  4FAK A;  4YPW A;  4RG1 A;  4YVI A;  4JWJ A;  5CO4 A;  4JAL A;  4MCD A;  4YQG A;  3DCM X;  3KTY A;  4XBO A;  1O6D A;  4IG6 A;  4YVH A;  3IC6 A;  4MCC A;  5FAI A;  3KNU A;  1TO0 A;  3L8U A;  5GMC A;  4KDZ A;  2O3A A;  4YQJ A;  1X7O A;  1V2X A;  4YQK A;  2QMM A;  1X7P A;  3NK6 A;  4H3Y A;  4YQ8 A;  4YVG A;  4YQ2 A;  1UAM A;  3BBE A;  4X3L A;  4YQA A;  3OII A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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